The effect of circadian rhythm on the perceived tinnitus severity: A preliminary study.

Related Articles

The effect of circadian rhythm on the perceived tinnitus severity: A preliminary study.

Int Tinnitus J. 2014;19(1):41-5

Authors: Zacharia T, James J, Prakash H, Mohan RT, Rajashekhar B

Abstract
INTRODUCTION: Hearing sound that does not originate in the world outside the body is an experience every human has at one time or another in life. Circadian rhythm is common for all living organisms and nearly all physiological functions, especially sleep-wake cycles, exhibit circadian rhythmicity. A short survey conducted in the study center revealed that majority of the tinnitus subjects reported a difference in tinnitus severity across the day. So the current study focused on finding out the influence of circadian rhythm on tinnitus severity.
MATERIALS & METHODS: Study was conducted on 20 tinnitus subjects irrespective of age, gender, hearing status and type of tinnitus. Kannada version of MEQ was given to all the subjects to classify them to various circadian types. A visual analog scale was also given to rate the severity of the tinnitus in the morning and evening.
RESULTS: The result of the current study states that, there was a significant difference in the tinnitus severity for moderate morning type individuals in the morning and evening and not for the intermediate group.
CONCLUSION: So we can conclude that, circadian rhythm has a strong association with the severity of the tinnitus.

PMID: 27186832 [PubMed - in process]

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Development and standardization of Morningness-Eveningness Questionnaire (MEQ) in the Indian language Kannada.

Related Articles

Development and standardization of Morningness-Eveningness Questionnaire (MEQ) in the Indian language Kannada.

Int Tinnitus J. 2014;19(1):36-40

Authors: Zacharia T, James J, Prakash H, Mohan RT, Rajashekhar B

Abstract
INTRODUCTION: A circadian rhythm is any biological process that displays an endogenous, entrainable, oscillation of about 24 hours; the rhythms driven by a circadian clock and sleep have been widely observed in plants, animals, fungi and cyanobacteria. The main aim of the current study was to translate and validate the Morningness-Eveningness Questionnaire (MEQ) to Kannada (MEQ-K).
MATERIALS AND METHODS: The English version of MEQ was translated to Kannada using translation-back-translation method. Further it was given to 30 native Kannada speakers for content validation. The final MEQ-Kannada version was then administered on 93 normal native Kannada speakers. Statistical analysis was carried out using SPSS 17.0 software. Statistics such as mean, standard deviation and variance and reliability statistics such as Cronbach's alpha score as well as item-total correlation were obtained.
RESULTS: RESULTS showed that, MEQ-K has a Cronbach's alpha score of 0.870 which is considered to be of good reliability. It was also observed that, even after deletion of any one item from the MEQ-K, the Cronbach's alpha score remained the same.
CONCLUSION: From the current results it can be stated that, MEQ-K is a reliable tool that can categorize Kannada speaking population into various circadian types.

PMID: 27186831 [PubMed - in process]

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Gastric peroral endoscopic pyloromyotomy (G-POEM) as a salvage therapy for refractory gastroparesis: a case series of different subtypes.

Gastric peroral endoscopic pyloromyotomy (G-POEM) as a salvage therapy for refractory gastroparesis: a case series of different subtypes.

Neurogastroenterol Motil. 2016 May 15;

Authors: Mekaroonkamol P, Li LY, Dacha S, Xu Y, Keilin SD, Willingham FF, Cai Q

Abstract
BACKGROUND: Gastroparesis is a poorly understood, chronic, debilitating motility disorder with very limited medical therapeutic options. Gastric peroral endoscopic pyloromyotomy (G-POEM) is an emerging novel endoscopic technique as an incisionless pyloroplasty for refractory cases. Effective information of G-POEM on different types of gastroparesis is sparse.
METHODS: Cases of G-POEM using selective circular myotomy as a salvage therapy for refractory symptoms were retrospective studied. The G-POEM procedures were performed by a single expert endoscopist under a certain protocol. Gastroparesis Cardinal Symptoms Index (GCSI) and gastric emptying scintigraphy (GES) were evaluated before and after the procedure. Procedures related adverse event were also recorded.
KEY RESULTS: All procedures were successfully completed without complications. Each case in this series was different in demography and etiology of gastroparesis, namely postsurgical, postinfectious, and idiopathic gastroparesis in an elderly male and two young female adults. All cases were refractory to conventional treatment but demonstrated obvious success after G-POEM as a salvage therapy both clinically and on GES.
CONCLUSIONS & INFERENCES: G-POEM as a salvage therapy improves symptoms and gastric emptying in patients with different types of refractory gastroparesis. Our cases are also the firsts to show success of G-POEM in postinfectious gastroparesis and in elderly male patient. More data are needed to determine which subgroup of patients would benefit most from this novel procedure.

PMID: 27197717 [PubMed - as supplied by publisher]

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Role of worry in patients with chronic tinnitus and sensorineural hearing loss: a preliminary study.

Role of worry in patients with chronic tinnitus and sensorineural hearing loss: a preliminary study.

Eur Arch Otorhinolaryngol. 2016 May 19;

Authors: Caldirola D, Teggi R, Daccò S, Sangiorgio E, Bussi M, Perna G

Abstract
Tinnitus-related distress appears to be more strongly associated with multiple psychological factors than with any perceptual properties of tinnitus. Prior studies have not investigated the role of worry in tinnitus sufferers. Worry is a dispositional cognitive trait that involves a pervasive, non-specific, future-oriented proneness to fretting, which can foster negative affective states and catastrophic thinking about a specific trouble when the trouble is actual and present. We examined the relationship between worry and self-perceived anxiety and depressive symptoms and handicap in 54 outpatients with chronic tinnitus and sensorineural hearing loss who had been previously recruited for a randomized double-blind study on the efficacy of transmeatal low-level laser therapy for tinnitus. We measured the current anxiety and depressive symptoms with the State-Trait Anxiety Inventory Form Y-1/Self-evaluation Depression Scale, the handicap with the Tinnitus Handicap Inventory, and the proneness to worry with the Penn State Worry Questionnaire. For the psychoacoustic tinnitus measures, we considered the loudness match and the minimum masking level. We found that tinnitus-related anxiety and depressive symptoms and handicap were significantly associated with proneness to worry (linear regression models, p < 0.01), whereas no associations were found with the psychoacoustic measures. This suggests the usefulness of worry assessment when managing chronic tinnitus in clinical practice. Early therapeutic interventions for reducing proneness to worry may facilitate better adaptation to tinnitus.

PMID: 27197727 [PubMed - as supplied by publisher]

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Authors' reply.

Authors' reply.

J Laryngol Otol. 2016 Feb;130(2):210

Authors: Larsen K

PMID: 27200446 [PubMed - indexed for MEDLINE]

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Optimal outcomes for hearing preservation in the management of small vestibular schwannomas.

Optimal outcomes for hearing preservation in the management of small vestibular schwannomas.

J Laryngol Otol. 2016 May 20;:1-5

Authors: Peng KA, Wilkinson EP

Abstract
OBJECTIVE: To undertake a systematic review of the role of microsurgery, in relation to observation and stereotactic radiation, in the management of small vestibular schwannomas with serviceable hearing.
METHODS: The Medline database was searched for publications that included the terms 'vestibular schwannoma' and/or 'acoustic neuroma', occurring in conjunction with 'hearing'. Articles were manually screened to identify those concerning vestibular schwannomas under 1.5 cm in greatest dimension. Thereafter, only publications discussing both pre-operative and post-operative hearing were considered.
RESULTS: Twenty-six papers were identified. Observation is an acceptable strategy for small tumours with slow growth where hearing preservation is not a consideration. In contrast, microsurgery, including the middle fossa approach, may provide excellent hearing outcomes, particularly when a small tumour has begun to cause hearing loss. Immediate post-operative hearing usually predicts long-term hearing. Recent data on stereotactic radiation suggest long-term deterioration of hearing following definitive therapy.
CONCLUSION: In patients under the age of 65 years with small vestibular schwannomas, microsurgery via the middle fossa approach offers durable preservation of hearing.

PMID: 27198728 [PubMed - as supplied by publisher]

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Letter to the Editor regarding squamoid pattern of anaplastic thyroid carcinoma, a poorly recognized entity.

Letter to the Editor regarding squamoid pattern of anaplastic thyroid carcinoma, a poorly recognized entity.

Head Neck. 2016 May 19;

Authors: Cabanillas ME, Williams MD

PMID: 27198734 [PubMed - as supplied by publisher]

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Reply to Letter to the Editor regarding anaplastic thyroid carcinoma.

Reply to Letter to the Editor regarding anaplastic thyroid carcinoma.

Head Neck. 2016 May 19;

Authors: Ryan NA, Lazic D

PMID: 27198627 [PubMed - as supplied by publisher]

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Impact of parathyroidectomy for primary hyperparathyroidism on quality of life: A case-control study using Short Form Health Survey 36.

Impact of parathyroidectomy for primary hyperparathyroidism on quality of life: A case-control study using Short Form Health Survey 36.

Head Neck. 2016 May 20;

Authors: Dulfer R, Geilvoet W, Morks A, van Lieshout EM, Smit CP, Nieveen van Dijkum EJ, In't Hof K, van Dam F, van Eijck CH, de Graaf PW, van Ginhoven TM

Abstract
BACKGROUND: Physical and mental complaints are common in patients with primary hyperparathyroidism (PHPT) and negatively impact quality of life (QOL). Subjective symptoms in current guidelines are not considered an indication for surgery. The purpose of this study was to assess the effect of parathyroidectomy on QOL in patients with PHPT.
METHODS: This multicenter case-control study investigated preoperative and postoperative QOL scores in patients operated for PHPT, measured with the Short Form Health Survey-36 (SF-36) questionnaire. Results were compared with patients undergoing a hemithyroidectomy, the control group.
RESULTS: Fifty-two patients and 49 controls were included. Patients with PHPT had significantly lower QOL scores preoperatively and improved significantly after successful surgical treatment. Postoperatively, no differences were observed between the 2 groups.
CONCLUSION: QOL was significantly lower in patients with untreated PHPT. Surgical treatment was associated with a significant increase in QOL. Decreased QOL should also be considered as an indicator for surgical treatment in patients with PHPT. © 2016 Wiley Periodicals, Inc. Head Neck, 2016.

PMID: 27198205 [PubMed - as supplied by publisher]

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Severe laryngeal stenosis in newly born twins with 22q11.2 deletion syndrome: A case report.

Severe laryngeal stenosis in newly born twins with 22q11.2 deletion syndrome: A case report.

J Neonatal Perinatal Med. 2016 May 18;

Authors: Clive B, Corsten G, Penney LS, Van den Hof M, El-Naggar W

Abstract
Chromosome 22q11.2 deletion syndrome is common and presents with a range of clinical features from cardiac malformations to hypocalcemia. Laryngeal anomalies are not a common feature of this syndrome. We describe newly born twins who presented with unexpected severe birth depression secondary to severe type IV glottic webs requiring extensive resuscitation and emergency tracheostomy. They were diagnosed postnatally to have deletion of 22q11.2. The successful resuscitation of these infants at birth was only possible because they were born in a tertiary care hospital. This report shows the critical nature of prenatal diagnosis of 22q11.2 deletion syndrome.

PMID: 27197926 [PubMed - as supplied by publisher]

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Development of a bilayer ring system for achieving high strain in commercial rheometers.

Related Articles

Development of a bilayer ring system for achieving high strain in commercial rheometers.

J Biomech. 2015 Sep 18;48(12):3512-6

Authors: Christensen MB, Wolchok JC, Klemuk SA, Titze IR

Abstract
Mechanical stimulation of cell cultures has been shown be an effective means of enhancing ECM production. ECM produced from vocal fold fibroblast cultures has the potential for therapeutic use for vocal fold repair. However, current bioreactor designs generally fail to produce physiological relevant frequency and strain values. Here we present an approach for using commercial oscillatory rheometers and an elastic ring bilayer system to produce physiologically relevant strain values at frequencies in the range of 20-100 Hz. We demonstrate the ability to target specific strain and frequency values by manipulating system parameters, and also show that it is possible to maintain high oscillatory strains for extended periods of time. Such a system could be used to mechanically stimulate cell cultures contained within gel carrier systems and has the potential to be extended to other applications requiring high strains at low frequencies.

PMID: 26228712 [PubMed - indexed for MEDLINE]

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Cochlear Implant Impedance Fluctuation in Ménière's Disease: A Case Study.

Cochlear Implant Impedance Fluctuation in Ménière's Disease: A Case Study.

Otol Neurotol. 2016 May 19;

Authors: McNeill C, Eykamp K

Abstract
OBJECTIVE: To contribute to the understanding of hearing fluctuation in Ménière's disease (MD) by disseminating a case study of a cochlear implanted ear with ongoing fluctuation of electrode impedances with episodic tinnitus and no associated vestibular symptoms.
STUDY DESIGN: Retrospective case review.
SETTING: Tertiary referral audiology clinic.
PATIENT: Man, born in 1936, with a total hearing loss in the right ear because of Mumps at age 8 years and a fluctuating progressive hearing loss in the left ear because of Ménière's disease since age 63 years.
INTERVENTION: Sequential bilateral cochlear implantation right ear in August 2002 and left ear in March 2006.
MAIN OUTCOME MEASURE: Impedance measurements of implanted intracochlear electrodes via common ground stimulation using proprietor programming software.
RESULTS: Electrode impedances in the MD showed significant ongoing variation since implantation, whereas the contralateral non-MD ear remained stable over a period of 9 years.
CONCLUSION: Electrode impedances in the ear with MD showed a variation pattern similar to that found in the hearing fluctuation characteristic of the disease. These findings raise the possibility that the same physiological mechanisms of hearing fluctuation may be responsible for intracochlear electrode impedance changes. We hypothesize that impedance fluctuation is because of changes in the permeability of the blood-labyrinth barrier because of cyclic immune activity in the inner ear which alters the electrical resistance between scala tympani and blood.

PMID: 27203844 [PubMed - as supplied by publisher]

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Transient Hearing Loss and Objective Tinnitus Induced by Mouth Opening: A Rare Connection Between the Temporomandibular Joint and Middle Ear Space.

Transient Hearing Loss and Objective Tinnitus Induced by Mouth Opening: A Rare Connection Between the Temporomandibular Joint and Middle Ear Space.

Otol Neurotol. 2016 May 19;

Authors: Hidaka H, Tatewaki Y, Sakamoto M, Kobayashi T, Yuasa Y, Yuasa R, Nomura K, Yamauchi D, Katori Y

Abstract
OBJECTIVES: To describe objective tinnitus complicated with transient low-tone hearing loss coinciding with mouth opening, which was related to the connection between the mandibular fossa and middle ear space.
PATIENTS: A 41-year-old man presented with tinnitus, ear fullness, and hearing loss in the left ear on mouth opening.
MAIN OUTCOME MEASURES: Clinical case records, audiological data, and radiological analyses including computed tomography (CT) and magnetic resonance imaging.
RESULTS: Hearing thresholds on the affected side, which were evaluated with mouth opening, showed elevations of approximately 20 dB in the frequencies below 1000 Hz. Again, peak pressure on the tympanogram deviated negatively to -220 mmH2O under mouth opening without changing peak amplitude. CT showed a connection between the mandibular fossa and middle ear space, as revealed by a gas collection around the joint capsule evaluated in two phases (with and without mouth closing). Ear symptoms resolved after myringotomy.
CONCLUSIONS: Although an influence of temporomandibular disorder (TMD) on tinnitus perception has been debated, whether this association is causal or fortuitous has remained contentious. The present case showed a unique feature of tinnitus attributed to a connection between the mandibular fossa and middle ear space.

PMID: 27203846 [PubMed - as supplied by publisher]

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Cochlear Implant Impedance Fluctuation in Ménière's Disease: A Case Study.

Cochlear Implant Impedance Fluctuation in Ménière's Disease: A Case Study.

Otol Neurotol. 2016 May 19;

Authors: McNeill C, Eykamp K

Abstract
OBJECTIVE: To contribute to the understanding of hearing fluctuation in Ménière's disease (MD) by disseminating a case study of a cochlear implanted ear with ongoing fluctuation of electrode impedances with episodic tinnitus and no associated vestibular symptoms.
STUDY DESIGN: Retrospective case review.
SETTING: Tertiary referral audiology clinic.
PATIENT: Man, born in 1936, with a total hearing loss in the right ear because of Mumps at age 8 years and a fluctuating progressive hearing loss in the left ear because of Ménière's disease since age 63 years.
INTERVENTION: Sequential bilateral cochlear implantation right ear in August 2002 and left ear in March 2006.
MAIN OUTCOME MEASURE: Impedance measurements of implanted intracochlear electrodes via common ground stimulation using proprietor programming software.
RESULTS: Electrode impedances in the MD showed significant ongoing variation since implantation, whereas the contralateral non-MD ear remained stable over a period of 9 years.
CONCLUSION: Electrode impedances in the ear with MD showed a variation pattern similar to that found in the hearing fluctuation characteristic of the disease. These findings raise the possibility that the same physiological mechanisms of hearing fluctuation may be responsible for intracochlear electrode impedance changes. We hypothesize that impedance fluctuation is because of changes in the permeability of the blood-labyrinth barrier because of cyclic immune activity in the inner ear which alters the electrical resistance between scala tympani and blood.

PMID: 27203844 [PubMed - as supplied by publisher]

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Microvascular decompression for tinnitus: systematic review.

Microvascular decompression for tinnitus: systematic review.

J Neurosurg. 2016 May 20;:1-10

Authors: Nash B, Carlson ML, Van Gompel JJ

Abstract
OBJECTIVE The objective of this study was to examine operative outcomes in cases of microvascular decompression (MVD) of cranial nerve (CN) VIII for tinnitus through a critical review of the literature. METHODS Forty-three English-language articles were gathered from PubMed and analyzed. In this review, two different case types were distinguished: 1) tinnitus-only symptomatology, which was defined as a patient with tinnitus with or without sensorineural hearing loss; and 2) mixed symptomatology, which was defined as tinnitus with symptoms of other CN dysfunction. This review reports outcomes of those with tinnitus-only symptoms. RESULTS Forty-three tinnitus-only cases were found in the literature with a 60% positive outcome rate following MVD. Analysis revealed a 5-year cutoff of preoperative symptom duration before which a good outcome can be predicted with 78.6% sensitivity, and after which a poor outcome can be predicted with 80% specificity. CONCLUSIONS As the 60% success rate is more promising than several other therapeutic options open to the chronic tinnitus sufferer, future research into this field is warranted.

PMID: 27203146 [PubMed - as supplied by publisher]

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Venous sinus stenting in patients without idiopathic intracranial hypertension.

Venous sinus stenting in patients without idiopathic intracranial hypertension.

J Neurointerv Surg. 2016 May 19;

Authors: Levitt MR, Albuquerque FC, Gross BA, Moon K, Jadhav AP, Ducruet AF, Crowley RW

Abstract
BACKGROUND: Venous sinus stenting is an effective treatment for patients with idiopathic intracranial hypertension (IIH) and venous sinus stenosis.
OBJECTIVE: To determine the usefulness of venous sinus stenting in the treatment of patients with symptomatic venous sinus stenosis without a diagnosis of IIH.
METHODS: We performed a retrospective review of a prospective multicenter database of patients undergoing venous sinus stenting between January 2008 and February 2016. Patients with acute dural venous sinus thrombosis, arteriovenous fistula or arteriovenous malformation, or IIH were excluded. Clinical, radiological, and ophthalmological information was recorded.
RESULTS: Nine patients met the inclusion criteria and underwent venous sinus stenting for symptomatic dural venous sinus stenosis. Reasons for treatment included isolated unilateral pulsatile tinnitus (n=1), congenital hydrocephalus (n=2), unilateral pulsatile tinnitus following prior venous sinus thrombosis (n=1), acquired hydrocephalus following dural sinus thrombosis (n=2), meningitis (n=2) and tumor invasion into the dural venous sinus (n=1). Six patients underwent lumbar puncture or shunt tap, and all of these patients had elevated intracranial pressure. All stenoses were located in the transverse sinus, transverse-sigmoid junction and/or jugular bulb, and all were treated with self-expanding bare-metal stents. At follow-up, clinical symptoms had resolved in all but two patients, both of whom had congenital hydrocephalus and pre-existing shunts. There was no significant in-stent stenosis, and patients with ophthalmological follow-up demonstrated improvement of papilledema.
CONCLUSIONS: Dural venous sinus stenting may be an effective treatment for patients with symptomatic venous sinus stenosis without IIH in carefully selected cases, but may not be effective in resolving the symptoms of congenital hydrocephalus.

PMID: 27199383 [PubMed - as supplied by publisher]

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Association Between Headaches and Tinnitus in Young Adults: Cross-Sectional Study.

Association Between Headaches and Tinnitus in Young Adults: Cross-Sectional Study.

Headache. 2016 May 20;

Authors: Guichard E, Montagni I, Tzourio C, Kurth T

Abstract
OBJECTIVE: To study the association between migraine and tinnitus in a large, cross-sectional study among students.
BACKGROUND: Tinnitus has been associated with various pain syndromes, including headaches. However, prior studies were mainly conducted among elderly adults.
METHODS: Cross-sectional study among 5729 participants of the French internet-based Students Health Research Enterprise (i-Share) cohort. Health, personal and lifestyle habits, and socio-demographics characteristics as well as headache/migraine symptoms and tinnitus, were recorded in a standardized questionnaire based on self-reports. Logistic regression models were used to evaluate the association between the students' headache status and tinnitus.
RESULTS: The 5729 participants had a mean age of 20.8 years (standard deviation 2.8 years), 75.4% were female, and 1645 reported migraine. An association was found between the students' headache status and tinnitus after adjustment for confounding variables. Tinnitus was reported by 8.9% of participants with migraine, 7.3% of patients with migraine without aura, and 10.8% of participants with migraine with aura. The adjusted odds ratios of tinnitus were 1.77 (95% confidence interval, 1.36-2.30) for migraine and 1.38 (0.98-1.92) for non-migraine headache. The association was stronger for students with migraine with aura (odds ratio = 2.10, 95% confidence interval 1.54-2.86) than for migraine without aura (odds ratio = 1.51, 95% confidence interval 1.09-2.07).
CONCLUSION: We found an association between migraine and tinnitus among young individuals, which was strongest for the subgroup migraine with aura.

PMID: 27197786 [PubMed - as supplied by publisher]

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Role of worry in patients with chronic tinnitus and sensorineural hearing loss: a preliminary study.

Role of worry in patients with chronic tinnitus and sensorineural hearing loss: a preliminary study.

Eur Arch Otorhinolaryngol. 2016 May 19;

Authors: Caldirola D, Teggi R, Daccò S, Sangiorgio E, Bussi M, Perna G

Abstract
Tinnitus-related distress appears to be more strongly associated with multiple psychological factors than with any perceptual properties of tinnitus. Prior studies have not investigated the role of worry in tinnitus sufferers. Worry is a dispositional cognitive trait that involves a pervasive, non-specific, future-oriented proneness to fretting, which can foster negative affective states and catastrophic thinking about a specific trouble when the trouble is actual and present. We examined the relationship between worry and self-perceived anxiety and depressive symptoms and handicap in 54 outpatients with chronic tinnitus and sensorineural hearing loss who had been previously recruited for a randomized double-blind study on the efficacy of transmeatal low-level laser therapy for tinnitus. We measured the current anxiety and depressive symptoms with the State-Trait Anxiety Inventory Form Y-1/Self-evaluation Depression Scale, the handicap with the Tinnitus Handicap Inventory, and the proneness to worry with the Penn State Worry Questionnaire. For the psychoacoustic tinnitus measures, we considered the loudness match and the minimum masking level. We found that tinnitus-related anxiety and depressive symptoms and handicap were significantly associated with proneness to worry (linear regression models, p < 0.01), whereas no associations were found with the psychoacoustic measures. This suggests the usefulness of worry assessment when managing chronic tinnitus in clinical practice. Early therapeutic interventions for reducing proneness to worry may facilitate better adaptation to tinnitus.

PMID: 27197727 [PubMed - as supplied by publisher]

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[Extramedullary relapse of acute lymphoblastic leukemia in the mastoid after allogeneic hematopoietic stem cell transplantation: a case report].

[Extramedullary relapse of acute lymphoblastic leukemia in the mastoid after allogeneic hematopoietic stem cell transplantation: a case report].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2016 Jan;30(1):72-3

Authors: Dong F, Wang N, Liu R

Abstract
Extramedullary relapse of acute lymphoblastic leukemia (ALL) in the mastoid after allogeneic hematopoietic stem cell transplantation (allo-HSCT) is rare. In this paper, we describe such an uncommon case of extramedullary relapse of ALL in the mastoid. The patient, who had been diagnosed as having ALL and underwent an allo-HSCT from his matched sibling donor. Eight months after allo-HSCT, he presented with ear-ache, tinnitus. The middle ear mastoid CT revealed otomastoiditis. The patient underwent operation. After pathological examination, the definited diagnosis was made that the patient was extramedullary relapse of ALL in the mastoid. We should pay more attention to the patients with hemopathy, which can help to improve early diagnosis.

PMID: 27197463 [PubMed - in process]

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[The progress of inner ear malformation in radiological research].

[The progress of inner ear malformation in radiological research].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2016 Jan;30(1):88-90

Authors: Kong D, Fu K, Zhao H

Abstract
Inner ear malformations are anomalies linking to development insults at different periods of embryogenesis,which are common causes of congenital sensorineural hearing loss. The evaluation of pediatric sensorineural hearing loss mostly depends on high-resolution computed tomography and magnetic resonance imaging, which can excellently depict the temporal bones and inner ear malformations.

PMID: 27197469 [PubMed - in process]

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