Αρχειοθήκη ιστολογίου

Παρασκευή 4 Δεκεμβρίου 2015

OtoRhinoLaryngology & Medicine,New Articles,December 4th,2015,a

Breast cancer stem cells: are we ready to go from bench to bedside?

Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Since the discovery of breast cancer stem cells (BCSCs) more than 10 years ago, a body of exciting research has developed. The intrinsic properties of BCSCs, including self-renewal and the ability to give rise to heterogeneous progeny, make BCSCs a likely source of tumour initiation, heterogeneity, progression and metastasis. BCSCs are also inherently resistant to conventional therapies and are therefore thought to contribute to disease recurrence. In this review, we will focus on both the challenges and recent advances in the characterization of BCSCs with respect to phenotype, ... περισσότερα »

Annual Review Issue: Breast Pathology

Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
from Anatomy Pathology via xlomafota13 on Inoreader http://ift.tt/1RrIPTp via IFTTT

Ductal carcinoma in situ – update on risk assessment and management

Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Ductal carcinoma *in situ* (DCIS) accounts for ~20–25% of breast cancers. While DCIS is not life-threatening, it may progress to invasive carcinoma over time, and treatment intended to prevent invasive progression may itself cause significant morbidity. Accurate risk assessment is therefore necessary to avoid over- or undertreatment of an individual patient. In this review we will outline the evidence for current management of DCIS, discuss approaches to DCIS risk assessment and challenges facing identification of novel DCIS biomarkers. from Anatomy Pathology via xlomafota13 on ... περισσότερα »

Recommendations for excision following core needle biopsy of the breast: a contemporary evaluation of the literature

Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Pathologists frequently encounter non-malignant histological findings in percutaneous core needle biopsies (CNBs). Standards for the management of patients with lesions such as atypical ductal hyperplasia, atypical lobular hyperplasia, and lobular carcinoma *in situ*, as well as other benign lesions, are not well defined, and recommendations for surgical biopsy or continued clinical and radiological follow-up are inconsistent. The frequency with which these lesions are 'upgraded' to carcinoma in excision specimens is widely variable in the literature. Many CNB studies lack carefu... περισσότερα »

Οtosclerosis and osteoporosis

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 25 δευτερόλεπτα
Relation of otosclerosis and osteoporosis: A bone mineral density study: Otosclerosis and osteoporosis are metabolic bone diseases. In this paper, we investigated presence of osteoporosis with bone mineral density test in patients who had surgery for otosclerosis. AbstractObjective Otosclerosis and osteoporosis are metabolic bone diseases. In this paper, we investigated presence of osteoporosis with bone mineral density test in patients who had surgery for otosclerosis. Methods We included 27 patients who had conductive hearing loss and diagnosed with otosclerosis during an explorat...περισσότερα »

Cholinergic deafferentation of the hippocampus causes non-temporally graded retrograde amnesia in an odor discrimination task

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 25 δευτερόλεπτα
[image: alertIcon.gif] Publication date: 15 February 2016 *Source:*Behavioural Brain Research, Volume 299 Author(s): Jenny R. Köppen, Sarah L. Stuebing, Megan L. Sieg, Ashley A. Blackwell, Philip A. Blankenship, Joseph L. Cheatwood, Douglas G. Wallace Dementia of the Alzheimer's type (DAT) is a neurodegenerative disorder marked by loss of hippocampal cholinergic tone and significant memory impairments, specifically for memories acquired prior to disease onset. The nature of this relationship, however, remains debated. The current study used the string pulling task to evaluate the tem...περισσότερα »

Mitigating aflatoxin exposure to improve child growth

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 55 δευτερόλεπτα
Mitigating aflatoxin exposure to improve child growth in Eastern Kenya: study protocol for a randomized controlled trial: Background: While the few studies that have looked at the association between stunting and aflatoxin exposure have found surprisingly large effects, the results remain inconclusive due to a lack of randomized controlled studies. This protocol describes a non-blinded, cluster-randomized controlled trial with the specific objective of testing the impact of reduced aflatoxin exposure on (individual) child linear growth.Methods/DesignParticipants were recruited from a... περισσότερα »

Photodynamic therapy for the endodontic treatment of primary teeth

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 55 δευτερόλεπτα
Evaluation of the effectiveness of photodynamic therapy for the endodontic treatment of primary teeth: study protocol for a randomized controlled clinical trial: Background: The elimination of pathogenic microorganisms from the root canal system is one of the major steps required for successful endodontic treatment. The aim of the proposed study is to conduct a randomized, controlled, clinical trial for the clinical and radiographic evaluation of the effectiveness of photodynamic therapy during the endodontic treatment of primary teeth. Methods: Thirty primary anterior teeth in childr... περισσότερα »

RhoA-JNK Regulates the E-Cadherin Junctions of Human Gingival Epithelial Cells

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 55 δευτερόλεπτα
The junctional epithelium (JE) is unique with regard to its wide intercellular spaces and sparsely developed intercellular junctions. Thus, knowledge of the molecular mechanisms that regulate the formation of the intercellular junctions of the junctional epithelium may be essential to understand the pathophysiology of the JE. HOK-16B cells, a normal human gingival epithelial cell line, were used to identify the molecules involved in the regulation of the formation of intercellular E-cadherin junctions between human gingival epithelial cells. Activation of c-Jun N-terminal kinase (... περισσότερα »

Low Signals on T2* and SWI Sequences in Patients with MS with Progressive Multifocal Leukoencephalopathy [LETTERS]

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 1 ώρα
from #Neuroscience via alexandrossfakianakis on Inoreader http://ift.tt/1NtYzPv via IFTTT

Reply: [letter]

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 1 ώρα
from #Neuroscience via alexandrossfakianakis on Inoreader http://ift.tt/1NtYzz7 via IFTTT

A Systematic Review and Meta-Analysis of Treatment and Outcome of Blister-Like Aneurysms [ADULT BRAIN]

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 1 ώρα
BACKGROUND AND PURPOSE: Blister-like aneurysms are uncommon but challenging lesions. Their small size and atypical location often make the diagnosis difficult. Microsurgery and endovascular procedures have been used for their treatment, but there is no consensus on the best treatment technique. We conducted a systematic review and meta-analysis of treatments and outcomes of these vascular lesions. MATERIALS AND METHODS: We reviewed English-language articles on "blood blister-like aneurysms" published between January 1997 and November 2014. All studies reporting patients with th... περισσότερα »

Radiographic Local Control of Spinal Metastases with Percutaneous Radiofrequency Ablation and Vertebral Augmentation [INTERVENTIONAL]

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 1 ώρα
BACKGROUND AND PURPOSE: Combination radiofrequency ablation and vertebral augmentation is an emerging minimally invasive therapy for patients with metastatic spine disease who have not responded to or have contraindications to radiation therapy. The purpose of this study was to evaluate the rate of radiographic local control of spinal metastases treated with combination radiofrequency ablation and vertebral augmentation. MATERIALS AND METHODS: We retrospectively reviewed our tumor ablation database for all patients who underwent radiofrequency ablation and vertebral augmentation...περισσότερα »

Asymptomatic Interhypothalamic Adhesions in Children [PEDIATRICS]

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 1 ώρα
SUMMARY: With the use of high-resolution MR imaging techniques, we have increasingly observed anomalies of the hypothalamus characterized by a band of tissue spanning the third ventricle between the hypothalami, often without associated clinical sequelae. Historically, hypothalamic anomalies are highly associated with symptoms referable to a hypothalamic hamartoma, midline congenital disorder, hypothalamic-pituitary dysfunction, or seizures, with very few asymptomatic patients reported. The interhypothalamic tissue described in our cohort was observed incidentally through the ro... περισσότερα »

Prevalence of Brain Microbleeds in Alzheimer Disease: A Systematic Review and Meta-Analysis on the Influence of Neuroimaging Techniques [ADULT BRAIN]

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 1 ώρα
BACKGROUND AND PURPOSE: The literature on the prevalence of Alzheimer disease–associated cerebral microbleeds assessed with MR imaging shows considerable heterogeneity in terms of imaging techniques and parameters. Our aim was to perform a meta-analysis of the role of imaging techniques, including image acquisition, field strength and scanner type, and clinical and demographic factors on the reported prevalence of microbleeds in Alzheimer disease. MATERIALS AND METHODS: The prevalence of microbleeds was examined with respect to a priori–selected moderating variables via meta-ana... περισσότερα »

RhoA-JNK Regulates the E-Cadherin Junctions of Human Gingival Epithelial Cells

The junctional epithelium (JE) is unique with regard to its wide intercellular spaces and sparsely developed intercellular junctions. Thus, knowledge of the molecular mechanisms that regulate the formation of the intercellular junctions of the junctional epithelium may be essential to understand the pathophysiology of the JE. HOK-16B cells, a normal human gingival epithelial cell line, were used to identify the molecules involved in the regulation of the formation of intercellular E-cadherin junctions between human gingival epithelial cells. Activation of c-Jun N-terminal kinase (... περισσότερα »

Light-Cured Self-Etch Adhesives Undergo Hydroxyapatite-Triggered Self-Cure

Light cure is a popular mode of curing for dental adhesives. However, it suffers from inadequate light delivery when the restoration site is less accessible, in which case a self-cure mechanism is desirable to salvage any compromised polymerization. We previously reported a novel self-cure system mediated by ethyl 4-(dimethylamino)-benzoate (4E) and hydroxyapatite (HAp). The present work aims to investigate if such self-cure phenomenon takes place in adhesives that underwent prior inadequate light cure and to elucidate if HAp released from the dental etching process is sufficient t...περισσότερα »

Atypical Femoral Fractures: Radiological Evaluation and Bisphosphonate Exposure.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Related Articles *Atypical Femoral Fractures: Radiological Evaluation and Bisphosphonate Exposure.* Isr Med Assoc J. 2015 Sep;17(9):554-8 Authors: Tripto-Shkolnik L, Segal E, Jaffe A, Ish-Shalom S, Bachrach R, Nachtigal A, Militianu D Abstract BACKGROUND: Evidence suggests that prolonged bisphosphonate (BP) treatment predisposes to atypical fractures (AF), but the etiology has yet to be determined. Addressing causality begins with case identification, which requires radiological adjudication. However, many trials based their case findings on coded diagnoses. OBJECTIVES: To inves... περισσότερα »

Periodontal Conditions and Tumor Necrosis Factor-Alpha Level in Gingival Crevicular Fluid of Scleroderma Patients.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Related Articles *Periodontal Conditions and Tumor Necrosis Factor-Alpha Level in Gingival Crevicular Fluid of Scleroderma Patients.* Isr Med Assoc J. 2015 Sep;17(9):549-53 Authors: Elimelech R, Mayer Y, Braun-Moscovici Y, Machtei EE, Balbir-Gurman A Abstract BACKGROUND: Systemic sclerosis (SSc) is a chronic disease with prominent vasculopathy, inflammation, production of autoantibodies, and tissue fibrosis. Periodontitis is a chronic inflammatory oral condition manifesting as microbial infection, inflammation and destruction of the alveolar bone. In both conditions tumor necros...περισσότερα »

Should Intravenous Contrast be Administered in MRI Evaluation of Pediatric Outpatients with Chronic Headache?

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Related Articles *Should Intravenous Contrast be Administered in MRI Evaluation of Pediatric Outpatients with Chronic Headache?* Isr Med Assoc J. 2015 Sep;17(9):545-8 Authors: Tal S, Abrahamy M, Gottlieb P, Maresky H, Ben Ely A Abstract BACKGROUND: The practice of administering intravenous contrast to children varies by institution depending on their routine. OBJECTIVES: To assess the necessity of routine contrast administration in brain magnetic resonance imaging (MRI) of pediatric outpatients referred for chronic headache workups. METHODS: We conducted a retrospective review of ...περισσότερα »

Management of Complicated Gastric Bezoars in Children and Adolescents.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Related Articles *Management of Complicated Gastric Bezoars in Children and Adolescents.* Isr Med Assoc J. 2015 Sep;17(9):541-4 Authors: Castle SL, Zmora O, Papillon S, Levin D, Stein JE Abstract BACKGROUND: Gastric bezoars in children are infrequent. Most are trichobezoars. Surgical intervention is sometimes necessary. OBJECTIVES: To describe the clinical findings and radiological workup, as well as treatment and outcome of patients with complicated gastric bezoars who underwent surgery in our institution. METHODS: We conducted a retrospective review of all cases of surgery for g...περισσότερα »

Left Cardiac Sympathetic Denervation in Patients with CASQ2-Associated Catecholaminergic Polymorphic Ventricular Tachycardia.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Related Articles *Left Cardiac Sympathetic Denervation in Patients with CASQ2-Associated Catecholaminergic Polymorphic Ventricular Tachycardia.* Isr Med Assoc J. 2015 Sep;17(9):538-40 Authors: Marai I, Boulos M, Khoury A Abstract BACKGROUND: Left cardiac sympathetic denervation (LCSD) was reported to be effective in patients with intractable ryanodine receptor mutation-associated catecholaminergic polymorphic ventricular tachycardia (CPVT). OBJECTIVES: To report our experience with LCSD in calsequestrin (CASQ2) mutation-associated CPVT. METHODS: LCSD was performed in three patien... περισσότερα »

The role of dietary potassium in hypertension and diabetes

Alexandros G. SfakianakisστοEvolutionary PhysiologyΠριν από 1 ώρα
Abstract Potassium is an essential mineral which plays major roles for the resting membrane potential and the intracellular osmolarity. In addition, for several years, it has been known that potassium also affects endothelial and vascular smooth muscle functions and it has been repeatedly shown that an increase in potassium intake shifts blood pressure to a more preferable level. Meanwhile, the blood pressure lowering effects of potassium were presented in several intervention trials and summarized in a handful of meta-analyses. Furthermore, accumulating epidemiological evidence fr... περισσότερα »

Garrison Clinical Setting Inadequate for Maintenance of Procedural Skills for Emergency Medicine Physicians: A Cross-Sectional Study.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 1 ώρα
Related Articles *Garrison Clinical Setting Inadequate for Maintenance of Procedural Skills for Emergency Medicine Physicians: A Cross-Sectional Study.* J Spec Oper Med. 2015;15(4):67-70 Authors: Schauer SG, Varney SM, Cox KL Abstract BACKGROUND: Emergency medicine physicians (EPs) are often placed in far-forward, isolated areas in theater. Maintenance of their emergency intervention skills is vital to keep the medical forces deployment ready. The US Army suggests that working at a Military Treatment Facility (MTF) is sufficient to keep emergency procedural skills at a deployment... περισσότερα »

Orofacial pain and the prospects of precision medicine.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 1 ώρα
Related Articles *Orofacial pain and the prospects of precision medicine.* J Oral Facial Pain Headache. 2015;29(4):321 Authors: Stohler CS PMID: 26625499 [PubMed - in process] from #ENT-PubMed via ola Kala on Inoreader http://ift.tt/1XLIOcw via IFTTT

The application of the linear quadratic model to compensate the effects of prolonged fraction delivery time on a Balb/C breast adenocarcinoma tumor: An in vivo study

Alexandros G. SfakianakisστοΠαθολοΑνατομίαΠριν από 1 ώρα
10.3109/09553002.2016.1117677<br>Safoora Nikzad from Anatomy Pathology via ola Kala on Inoreader http://ift.tt/1NtrGa4 via IFTTT

Activity and expression of acetylcholinesterase in PC12 cells exposed to intermittent 1.8 GHz 217-GSM mobile phone signal

Alexandros G. SfakianakisστοΠαθολοΑνατομίαΠριν από 1 ώρα
10.3109/09553002.2016.1114188<br>Paola Valbonesi from Anatomy Pathology via ola Kala on Inoreader http://ift.tt/1NtrGXN via IFTTT

Light-Cured Self-Etch Adhesives Undergo Hydroxyapatite-Triggered Self-Cure

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Light cure is a popular mode of curing for dental adhesives. However, it suffers from inadequate light delivery when the restoration site is less accessible, in which case a self-cure mechanism is desirable to salvage any compromised polymerization. We previously reported a novel self-cure system mediated by ethyl 4-(dimethylamino)-benzoate (4E) and hydroxyapatite (HAp). The present work aims to investigate if such self-cure phenomenon takes place in adhesives that underwent prior inadequate light cure and to elucidate if HAp released from the dental etching process is sufficient t...περισσότερα »

Spontaneous complete resolution of a radiolucent shadow associated with an impacted mandibular third molar

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Impacted third molars are commonly associated with areas of radiolucency, and treatment can damage the adjacent structures, specifically the inferior alveolar nerve. We report a rare and interesting case of a large radiolucent area associated with an impacted mandibular wisdom tooth that resolved over 7 years with no intervention. We postulate that the unexpected movement of the tooth over this time caused spontaneous resolution of the cystic space, a natural decompression, which highlights the option of monitoring. from OroFacial Medicine via ola Kala on Inoreader http://ift.tt/1...περισσότερα »

Results of radiological follow-up of untreated anterior disc displacement without reduction in adolescents

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Our aim was to assess the progression of disease without treatment in adolescents with non-reducible anterior disc displacement (ADD) using serial magnetic resonance images (MRI). We retrospectively reviewed all patients under the age of 20 years who had unilateral non-reducible ADD and had had two MRI during a period of 6 months with no intervention. A total of 124 patients (101 female and 23 male) with a mean (range) age of 16 (10-20) years had 2 MRI at least 6 months apart (mean (range) 14 (6-47) months). from OroFacial Medicine via ola Kala on Inoreader http://ift.tt/1YMtkr7 v...περισσότερα »

Combination of transconjunctival and lateral canthotomy with modified endaural approaches in midface osteogenic distraction

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Distraction osteogenesis is widely used in the treatment of craniofacial deformities when external or internal distraction devices are placed after the corresponding osteotomies. The external system is most common as it is possible to adjust it to correct the distraction vectors.1 Internal devices, however, are better accepted by patients, as they minimise the psychosocial impact.2 from OroFacial Medicine via ola Kala on Inoreader http://ift.tt/1lAdjG7 via IFTTT

Improved wound management at lower cost: a sensible goal for Australia

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 1 ώρα
Abstract Chronic wounds cost the Australian health system at least US$2·85 billion per year. Wound care services in Australia involve a complex mix of treatment options, health care sectors and funding mechanisms. It is clear that implementation of evidence-based wound care coincides with large health improvements and cost savings, yet the majority of Australians with chronic wounds do not receive evidence-based treatment. High initial treatment costs, inadequate reimbursement, poor financial incentives to invest in optimal care and limitations in clinical skills are major barrier...περισσότερα »

The effect of dispersed Petrobaltic oil droplet size on photosynthetically active radiation in marine environment

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 1 ώρα
Abstract Oil pollution in seawater, primarily visible on sea surface, becomes dispersed as an effect of wave mixing as well as chemical dispersant treatment, and forms spherical oil droplets. In this study, we examined the influence of oil droplet size of highly dispersed *Petrobaltic* crude on the underwater visible light flux and the inherent optical properties (IOPs) of seawater, including absorption, scattering, backscattering and attenuation coefficients. On the basis of measured data and Mie theory, we calculated the IOPs of dispersed *Petrobaltic* crude oil in constant conc... περισσότερα »

Hospital admissions due to diseases of arteries and veins peaked at physiological equivalent temperature −10 to 10 °C in Germany in 2009–2011

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 1 ώρα
Abstract We aimed to understand relationships of the weather as biometeorological and hospital admissions due to diseases of arteries and veins by subtypes, which have been scarcely studied, in a national setting in recent years. This is an ecological study. Ten percent of daily hospital admissions from the included hospitals (*n* = 1,618) across Germany that were available between 1 January 2009 and 31 December 2011 (*n* = 5,235,600) were extracted from Statistisches Bundesamt, Germany. We identified I70-I79 Diseases of arteries, arterioles and capillaries and I80-I89 Diseases of ...περισσότερα »

Assessment of selected metals in the ambient air PM 10 in urban sites of Bangkok (Thailand)

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 1 ώρα
Abstract Estimating the atmospheric concentrations of PM10-bounded selected metals in urban air is crucial for evaluating adverse health impacts. In the current study, a combination of measurements and multivariate statistical tools was used to investigate the influence of anthropogenic activities on variations in the contents of 18 metals (i.e., Al, Sc, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Se, Cd, Sb, Ba, La, Ce and Pb) in ambient air. The concentrations of PM10-bounded metals were measured simultaneously at eight air quality observatory sites during a half-year period at heavily t... περισσότερα »

No tillage combined with crop rotation improves soil microbial community composition and metabolic activity

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 1 ώρα
Abstract Soil microbial community can vary with different agricultural managements, which in turn can affect soil quality. The objective of this work was to evaluate the effects of long-term tillage practice (no tillage (NT) and conventional tillage (CT)) and crop rotation (maize-soybean (MS) rotation and monoculture maize (MM)) on soil microbial community composition and metabolic capacity in different soil layers. Long-term NT increased the soil organic carbon (SOC) and total nitrogen (TN) mainly at the 0–5 cm depth which was accompanied with a greater microbial abundance. The gr... περισσότερα »

Spontaneous complete resolution of a radiolucent shadow associated with an impacted mandibular third molar

Impacted third molars are commonly associated with areas of radiolucency, and treatment can damage the adjacent structures, specifically the inferior alveolar nerve. We report a rare and interesting case of a large radiolucent area associated with an impacted mandibular wisdom tooth that resolved over 7 years with no intervention. We postulate that the unexpected movement of the tooth over this time caused spontaneous resolution of the cystic space, a natural decompression, which highlights the option of monitoring. from #ΓναθοΧειρουργική via xlomafota13 on Inoreader http://ift.tt...περισσότερα »

Results of radiological follow-up of untreated anterior disc displacement without reduction in adolescents

Our aim was to assess the progression of disease without treatment in adolescents with non-reducible anterior disc displacement (ADD) using serial magnetic resonance images (MRI). We retrospectively reviewed all patients under the age of 20 years who had unilateral non-reducible ADD and had had two MRI during a period of 6 months with no intervention. A total of 124 patients (101 female and 23 male) with a mean (range) age of 16 (10-20) years had 2 MRI at least 6 months apart (mean (range) 14 (6-47) months). from #ΓναθοΧειρουργική via xlomafota13 on Inoreader http://ift.tt/1YMtkr7...περισσότερα »

Combination of transconjunctival and lateral canthotomy with modified endaural approaches in midface osteogenic distraction

Distraction osteogenesis is widely used in the treatment of craniofacial deformities when external or internal distraction devices are placed after the corresponding osteotomies. The external system is most common as it is possible to adjust it to correct the distraction vectors.1 Internal devices, however, are better accepted by patients, as they minimise the psychosocial impact.2 from #ΓναθοΧειρουργική via xlomafota13 on Inoreader http://ift.tt/1lAdjG7 via IFTTT

Age- and Level-Dependence of Fatty Infiltration in Lumbar Paravertebral Muscles of Healthy Volunteers [SPINE]

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 2 ώρες
BACKGROUND AND PURPOSE: Normative age-related decline in paravertebral muscle quality is important for reference to disease and risk identification in patients. We aimed to establish age- and vertebral level–dependence of paravertebral (multifidus and erector spinae) muscle volume and fat content in healthy adult volunteers. MATERIALS AND METHODS: In this prospective study multifidus and erector spinae fat signal fraction and volume at lumbar levels L1–L5 were measured in 80 healthy volunteers (10 women and men per decade, 20–62 years of age) by 2-point Dixon 3T MR imaging. ANO...περισσότερα »

Low Signals on T2* and SWI Sequences in Patients with MS with Progressive Multifocal Leukoencephalopathy [LETTERS]

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 2 ώρες
from Neurology via xlomafota13 on Inoreader http://ift.tt/1NtYzPv via IFTTT

Reply: [letter]

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 2 ώρες
from Neurology via xlomafota13 on Inoreader http://ift.tt/1NtYzz7 via IFTTT

A Systematic Review and Meta-Analysis of Treatment and Outcome of Blister-Like Aneurysms [ADULT BRAIN]

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 2 ώρες
BACKGROUND AND PURPOSE: Blister-like aneurysms are uncommon but challenging lesions. Their small size and atypical location often make the diagnosis difficult. Microsurgery and endovascular procedures have been used for their treatment, but there is no consensus on the best treatment technique. We conducted a systematic review and meta-analysis of treatments and outcomes of these vascular lesions. MATERIALS AND METHODS: We reviewed English-language articles on "blood blister-like aneurysms" published between January 1997 and November 2014. All studies reporting patients with th... περισσότερα »

Radiographic Local Control of Spinal Metastases with Percutaneous Radiofrequency Ablation and Vertebral Augmentation [INTERVENTIONAL]

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 2 ώρες
BACKGROUND AND PURPOSE: Combination radiofrequency ablation and vertebral augmentation is an emerging minimally invasive therapy for patients with metastatic spine disease who have not responded to or have contraindications to radiation therapy. The purpose of this study was to evaluate the rate of radiographic local control of spinal metastases treated with combination radiofrequency ablation and vertebral augmentation. MATERIALS AND METHODS: We retrospectively reviewed our tumor ablation database for all patients who underwent radiofrequency ablation and vertebral augmentation...περισσότερα »

Occurrence and controls on transport and transformation of nitrogen in riparian zones of Dongting Lake, China

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 2 ώρες
Abstract Dongting Lake is the second largest freshwater lake in China. It is suffering from significant eutrophication as a result of excessive nutrients inputs, among which nitrogen (N) is becoming a major contributor. The objective of this study is to document the occurrence and controls on N transport and transformation in riparian zones of Dongting Lake wetland. Field experiments were conducted in the cultivated Li River (LR) and uncultivated Yuan River (YR) regions of the wetlands from June to November, 2014. Groundwater depth, redox potential (Eh), pH, and temperature were m... περισσότερα »

Sensitivity of the deep-sea amphipod Eurythenes gryllus to chemically dispersed oil

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 2 ώρες
Abstract In the context of an oil spill accident and the following oil spill response, much attention is given to the use of dispersants. Dispersants are used to disperse an oil slick from the sea surface into the water column generating a cloud of dispersed oil droplets. The main consequence is an increasing of the sea water–oil interface which induces an increase of the oil biodegradation. Hence, the use of dispersants can be effective in preventing oiling of sensitive coastal environments. Also, in case of an oil blowout from the seabed, subsea injection of dispersants may offer... περισσότερα »

Effect of dimethyl phthalate (DMP) on germination, antioxidant system, and chloroplast ultrastructure in Cucumis sativus L.

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 2 ώρες
Abstract Pollution of agricultural soils caused by widely employed plastic products, such as phthalic acid esters (PAEs), are becoming widespread in China, and they have become a threat to human health and the environment. However, little information is available on the influence of PAEs on vegetable crops. In this study, effects of different dimethyl phthalate (DMP) treatments (0, 30, 50, 100, and 200 mg L−1) on seed germination and growth of cucumber seedlings were investigated. Although germination rate showed no significant difference compared to control, seed germination time ...περισσότερα »

Antimony (SbIII) reduces growth, declines photosynthesis, and modifies leaf tissue anatomy in sunflower ( Helianthus annuus L.)

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 2 ώρες
Abstract The role of antimony (Sb)—a non-essential trace metalloid—in physiological processes running in crops is still poorly understood. Present paper describes the effect of Sb tartrate (SbIII) on growth, Sb uptake, photosynthesis, photosynthetic pigments, and leaf tissue organization in young sunflower plants grown in hydroponics. We found that growth of below- and aboveground part was reduced with increasing concentration of Sb in the medium. Although Sb was mostly taken up by sunflower roots and only small part (1–2 %) was translocated to the shoots, decline in photosynthesis...περισσότερα »

Colonization and release processes of viruses and prokaryotes on artificial marine macroaggregates

Alexandros G. SfakianakisστοΛοίμωξηΠριν από 2 ώρες
Marine organic aggregates are sites of high of viral accumulation; however, still little is known about their colonization processes and interactions with their local bacterial hosts. By taking advantage of a novel approach (paramagnetic functionalized microsphere method) to create and incubate artificial macroaggregates, we examined the small-scale movements of viruses and bacteria between such marine snow particles and the surrounding water. The examination of the codynamics of both free-living and attached viral and bacterial abundance, over 12 hours of incubation in virus-free ...περισσότερα »

Effect of sonic stimulation on Bacillus endospore germination

Alexandros G. SfakianakisστοΛοίμωξηΠριν από 2 ώρες
This study investigates the effect of sonic stimulation on *Bacillus* endospore germination*.* Germinating endospores in a microtiter plate were exposed to audible sound wave generated by an array of piezoelectric transducers. *In situ* germination kinetics was measured by terbium-dipicolinate fluorescence assay, optical density measurement and phase contrast microscopy. Fluorescence results revealed that sonic stimulation (5 kHz at 90 dB) promoted the germination speed by 43.7% ± 11.3% and final germination level by 61.7% ± 11.9% of *Bacillus atrophaeus*. This acoustic energy abs...περισσότερα »

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