Reversal of Visual Impairment Associated with Vasospasm after Resection of Sphenoclinoidocavernous Meningioma with Intra-arterial Verapamil.

Reversal of Visual Impairment Associated with Vasospasm after Resection of Sphenoclinoidocavernous Meningioma with Intra-arterial Verapamil.

World Neurosurg. 2016 Jun 20;

Authors: Amuluru K, Al-Mufti F, Singh IP, Frohman LP, Gandhi CD, Liu JK

Abstract
BACKGROUND: Visual loss can be encountered in the immediate, early, or even delayed postoperative period after resection of skull base meningiomas involving the optic apparatus. Various mechanisms for visual loss can include mechanical injury, vascular insult, optic nerve and chiasm edema, and vasospasm of the blood supply to the visual apparatus.
DESCRIPTION: In this paper, we describe a patient who developed unilateral visual worsening in the early postoperative period after skull base resection of a sphenoclinoidocavernous meningioma that was compressing the ipsilateral optic nerve. After implementing hyperdynamic therapy and high-dose corticosteroids, catheter angiography demonstrated severe vasospasm of the ipsilateral ophthalmic artery with delayed filling of the choroidal blush. Intra-arterial chemical angioplasty with verapamil was administered which resulted in angiographic improvement and clinical restoration of vision back to preoperative baseline. Vision remained stable in the postoperative course and continued to improve after discharge from the hospital.
CONCLUSIONS: To our knowledge, this is the first report of successful reversal of postoperative unilateral visual loss related to vasospasm after resection of a skull base sphenoclinoidocavernous meningioma. This may be a useful strategy to diagnose and treat possible vasospasm-induced visual loss after resection of skull base meningiomas involving the optic apparatus.

PMID: 27338210 [PubMed - as supplied by publisher]

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