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Τετάρτη 14 Σεπτεμβρίου 2016

Intradural chordoma presenting with intratumoral bleeding.

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Intradural chordoma presenting with intratumoral bleeding.

J Clin Neurosci. 2016 Mar;25:139-42

Authors: Vellutini Ede A, de Oliveira MF

Abstract
Intradural clival chordomas are very rare, and only 29 cases have been reported to our knowledge. They arise purely intradurally without bone or dural involvement and may differ from classic clival chordomas in physiopathology and management. We present a 28-year-old woman who presented with intradural clival chordoma and tumoral bleeding. After initial gross macroscopic surgical resection, she presented with tumor recurrence after 2 years, again with intratumoral bleeding. Although usually considered to have a more favorable prognosis in comparison to typical chordomas, intradural chordomas appear to behave as typical chordomas. Intratumoral bleeding may be a sign of an aggressive lesion and risk of recurrence. We highlight the differential diagnosis of intrinsic posterior fossa bleeding, especially in young patients. Intradural chordomas may be underdiagnosed and incorrectly treated as other types of parenchymal hemorrhage.

PMID: 26563604 [PubMed - indexed for MEDLINE]



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