Severe underweight decreases the survival rate in adult lung transplantation

Abstract

Purpose

The body mass index (BMI) before lung transplantation (LT) is a benchmark of the post-LT survival. The aim of the study is to determine the BMI inadequate for the post-LT survival.

Methods

We examined the survival after LT in patients grouped into the following BMI categories: <18.5 kg/m² (underweight), 18.5–24.9 kg/m² (normal weight), 25–29.9 kg/m² (overweight), and ≥30.0 kg/m² (obese) according to the World Health Organization (WHO) criteria. A more detailed categorization was made for further evaluation of the underweight group: mild (17.0 ≤ BMI < 18.5 kg/m²) and severely underweight (BMI <17.0 kg/m²).

Results

There was no statistically significant difference in the post-LT survival between underweight and normal-weight patients (5-year survival: 78.7 vs. 76.1%). Patients with BMI <17.0 kg/m² had a worse prognosis than those with 17.0 ≤ BMI < 18.5 kg/m² (5-year survival: 70.3 vs. 90.0%).

Conclusions

Standard BMI categorization per the WHO criteria is inadequate for determining the post-LT survival, especially in underweight patients. For the nutritional evaluation of underweight pre-LT patients, BMI <17.0 kg/m² should be used instead of BMI <18.5 kg/m².

from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/2mYex1L