Αρχειοθήκη ιστολογίου

Παρασκευή 13 Οκτωβρίου 2017

Distribution of cervical metastasis in tongue cancer: Are occult metastases predictable? A retrospective study of 117 oral tongue carcinomas

Publication date: Available online 13 October 2017
Source:Journal of Cranio-Maxillofacial Surgery
Author(s): Paolo Cariati, Almudena Cabello Serrano, Jose Fernandez Solis, Ildefonso Martinez Lara
PurposeThe aims of this study were to evaluate the pattern of distribution of cervical metastasis in tongue cancer and to analyze the various therapeutic options available. Moreover, numerous histological features were analyzed to assess the impact of each factor on overall survival.Materials and MethodsA retrospective analysis was conducted using the records of patients diagnosed with oral tongue cancer between 2004 and 2010 in the HUVN. A total of 117 patients with squamous cell carcinoma of the tongue treated with glossectomy and selective neck dissection were included in the study. The pattern of distribution of cervical metastases and numerous histological features such as T-stage, N stage, surgical margins, tumor thickness, extracapsular spread (ECS) and vascular invasion were analyzed.ResultsLevel IIA was the most affected, followed by level III. The rate of skip metastasis was 7,4%. T and N stage, tumor thickness, ECS, surgical margins and nerve and vascular invasion were associated with poorer outcomes in terms of overall survival (p<0,001).ConclusionCervical nodal involvement represents the major prognostic factor in tongue cancer. A total of 51,2% of N+ patients presented T1 and T2 tumors in this series. We recommend performing neck dissection at the early stages in clinically N0 patients when a tumor thickness >0,4 cm is suspected. Level IV should be included in the neck dissection of clinically N0 tongue cancer.



from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/2ymSckj

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