Dyspnea or Cheyne-Stokes respiration associated with Ticagrelor?

A 65-year-old, 85 kg 182 cm man (author PB) known for ischemic heart disease with surgical revascularization in 2005, was admitted for non-ST-segment elevation myocardial infarction. At the end of successful right coronary artery stenting, Ticagrelor, a reversible inhibitor of P2Y12 receptor, was added to Aspirin. Five hours later, the patient complained of dyspnea and CSR difficult to repress while awake. At home his spouse recorded on a portable phone the abnormal pattern of periodic breathing during sleep, with apneas lasting up to 21 seconds.

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