A relapsed lower lip squamous cell carcinoma treated with curative electrochemotherapy in elderly patient.

A relapsed lower lip squamous cell carcinoma treated with curative electrochemotherapy in elderly patient.

Minerva Stomatol. 2017 Oct 31;:

Authors: Gargiulo M, Cortese A, Pantaleo G, Parascandalo S, Amato M

Abstract
INTRODUCTION: ECT is normally used in the treatment of basal cell carcinoma, cutaneous and subcutaneous tumours, metastases of melanoma, Kaposi sarcoma, because of its high power, safety and low toxicity. The ECT treatment efficacy depends on the drug concentration during the use, patient characteristics, the distribution of the electric field inside the tumour and the tumour characteristics.
AIM: The aim of this study was to evaluate the effect of ECT in a patient affected by relapsed lower lip squamous cell carcinoma, not candidate for traditional surgery but treated for persistent pain with swallowing and breathing difficulties.
MATERIALS AND METHODS: A 58-year-old caucasian man was referred with a relapsed lower lip squamous cell carcinoma. The patient showed a TNM staging system of T2N0M0. The patient was treated with ECT with midazolam, remifentanil and intravenous bleomycin therapy.
RESULTS: The results of the treatment performed on the patient in the study showed good subjective tolerance. The patient had no postoperative bleeding or swelling of the treated area. The 2 years follow up showed no local or regional relapse, echography was negative.
CONCLUSIONS: This study demonstrates that ECT is an effective therapeutic solution for relapsed lower lip squamous cell carcinoma. ECT treatment is a conservative surgery option with a reduced postoperative damage.

PMID: 29087094 [PubMed - as supplied by publisher]

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