Increased PT/SS may play an important role in the pathogenesis of lumbar spondylolisthesis with degenerative lumbar scoliosis

Publication date: March 2018
Source:Clinical Neurology and Neurosurgery, Volume 166
Author(s): Jinlei Zhang, Yong Hai, Jincai Yang, Aixing Pan, Yangpu Zhang
ObjectiveTo explore the clinical and spinopelvic features in patients with lumbar spondylolisthesis and degenerative lumbar scoliosis (LSDLS) and those with standalone lumbar spondylolisthesis (SALS).Patients and MethodsWe retrospectively analyzed 130 patients with lumbar spondylolisthesis seen between 05/2013 and 12/2016 in our hospital. Propensity score matching was used to reduce an age distribution imbalance between the two groups. Clinical and spinopelvic parameters were compared by independent samples t test and chi-square test. Nonlinear binary logistic regression analysis was used to analyze the independent factors.ResultsThere was no significant difference between groups for body mass index, level of intercrest line, level of spondylolisthesis, grade of spondylolisthesis, sagittal translation, segmental angulation, thoracic kyphosis, or sagittal vertical axis. The LSDLS group had significantly lower lumbar lordosis (LL) than the SALS group. The LSDLS group showed significantly greater pelvic tilt (PT) and ratio of PT to SS (sacral slope) (PT/SS), and lower SS. The pelvic incidence (PI) was not significantly different. The LSDLS group showed stronger significant differences in PT/SS compared to the SALS group. With each 0.1 increase in PT/SS, the risk of LSDLS increased 1.465 times.ConclusionsPatients with spondylolysis are less prone to development of DLS. Lower LL and SS, and higher PT are associated with the occurrence of LSDLS. Increased PT/SS may play an important role in the pathogenesis of LSDLS.



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