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Σάββατο 13 Ιανουαρίου 2018

Liponeurocytoma of the cerebello-pontine angle.

Liponeurocytoma of the cerebello-pontine angle.

World Neurosurg. 2018 Jan 08;:

Authors: Chiaramonte C, Rabaste S, Jacquesson T, Meyronet D, Cotton F, Jouanneau E, Berhouma M

Abstract
Liponeurocytoma is a very rare tumor classified as grade II (neuronal and mixed neuronal-glial tumors) according to 2016 WHO classification of Tumors of the Central Nervous System. The median age is 50-years-old and the most frequent location is the posterior cranial fossa especially within the cerebellar hemispheres; those arising in the cerebellopontine angle are exceptional. We herein report the clinical, radiological and pathological characteristics of a cerebellopontine angle liponeurocytoma in a 35-year-old woman. A review of the literature is also provided. This unusual cisternal location raises the issue of the differential imaging diagnosis with much more common cerebellopontine angle tumors (meningiomas, vestibular schwannomas, ependymomas, epidermoid cyst, hemangioblastomas and medulloblastomas). To the best of our knowledge 59 cases of cerebellar liponeurocytomas have been reported, including only 6 cases of cerebellopontine angle liponeurocytomas. The treatment relies on total removal whenever possible with an excellent prognosis, but a high MIB-1 index (>10%) and/or incomplete tumor resection are the main adverse prognostic factors.

PMID: 29325939 [PubMed - as supplied by publisher]



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