The prospective study of nigrostriatal dopaminergic function using by striatal dopamine transporter imaging (FMT/PET) in patients with idiopathic REM sleep behavior disorder

Introduction: In recent studies, some REM sleep behavior disorder (RBD) patients reported an increased risk to develop Lewy body-related diseases such as Parkinson's disease (PD) and dementia with Lewy bodies (DLB) and multiple system atrophy (MSA). Recent dopamine transporter SPECT and PET studies demonstrated decreased striatal dopaminergic innervations in some idiopathic RBD patients. Thus, we prospectively assessed a nigrostriatal dopaminergic function using by striatal dopamine transporter imaging in patients with idiopathic RBD and compared the finding with age matched healthy controls to clarify predictors of pathological neurodegenerative process of nigrostriatal dopaminergic neurons.

from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/2AkjvcC