A curious case of central odontogenic fibroma: A novel perspective

Chetana Chandrashekar, Subhalakshmi Sen, Venkadasalapathi Narayanaswamy, Raghu Radhakrishnan

Journal of Oral and Maxillofacial Pathology 2018 22(4):16-19

We appraise a case of central odontogenic fibroma (COF) with unusual histologic features of entrapped neural elements and mast cells. The presence of mast cells attributed to the release of stem cell factor, the principal growth and activating factor of mast cells. A putative role for C-kit and mast cells in the pathogenesis of COF is described.

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