Bilateral Spontaneous Regression of Vestibular Schwannoma in Neurofibromatosis Type 2

Publication date: May 2018
Source:World Neurosurgery, Volume 113
Author(s): Martina Sebök, Christiaan Hendrik Bas van Niftrik, Oliver Bozinov
BackgroundPatients with neurofibromatosis type 2 and bilateral vestibular schwannoma (VS) are frequently treated surgically for any tumor progression, and often repeated surgery or radiation treatment is even considered. Some VS progression occurs without the development of new clinical symptoms, or it does not progress in size over many years, even in the absence of any specific treatment.Case DescriptionA 61-year-old male patient with neurofibromatosis type 2 presented with bilateral VS. In a long-term follow-up, both had increased in size but also showed bilateral spontaneous regression during an 11-year follow-up period with a "watch-and-wait" strategy.ConclusionsWe emphasize conservative treatment ("watch and wait") in older patients even with long-term tumor progression without significant compression-related clinical symptoms.



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