Huntington disease (HD) is caused by the expression of mutant huntingtin (mHTT) bearing a polyglutamine expansion. In HD, mHTT accumulation is accompanied by a dysfunction in basal autophagy, which manifests a...
from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/2IxK0kv
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Σάββατο 17 Μαρτίου 2018
Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease
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