Histological Changes in the Periosteum Following Subperiosteal Expansion in Rabbit Scalp

Publication date: Available online 31 August 2017
Source:Journal of Oral and Maxillofacial Surgery
Author(s): Mohamad Taghi Kiani, Nasrin Takzare, Ahad Khoshzaban, Elahe Jalilianfar, Leila Aghajanpour, Reza Tabrizi
PurposeIn intraoral bone grafting, tension-free coverage of recipient site with periosteal flap results in optimal wound closure. Tissue expansion may be a suitable modality to obtain soft tissue in the oral cavity. The aim of this study was to assess the histology of periosteum following subperiosteal expansion in rabbit scalp.MethodsIn this animal study, six rectangular tissue expanders were placed in the skulls of six male white New Zeeland rabbits; in control rabbits, an incision was made to periosteum but no expansion was done. Three months after the surgeries, the rabbits were sacrificed and tissue samples were stained with hematoxylin and eosin and Masson's trichromeResultsThe number of osteoblasts, fibroblasts and blood vessels as well as the density of collagen fibers were significantly higher in the experimental group compared to the control group (P<0.001).ConclusionsSubperiosteal tissue expansion in rabbit scalp significantly increased the histologic components of the periosteum involved in bone regeneration.



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