Heterotopic thyroid autotransplantation: A preliminary clinical study.

Related Articles

Heterotopic thyroid autotransplantation: A preliminary clinical study.

Head Neck. 2017 Oct 27;:

Authors: Sakr M, El-Kerm Y, Abo-Elwafa W, Mahmoud A, Fathi I

Abstract
BACKGROUND: Thyroid autotransplantation offers an attractive alternative to subtotal thyroidectomy and replacement therapy. However, it has not been sufficiently clinically investigated.
METHODS: Total thyroidectomy was performed for 20 patients with benign thyroid disorders, and at least 10 g of thyroid tissue were implanted intramuscularly. Graft monitoring was achieved through (99m) Tc scan at 2 months, free triiodothyronine (FT3), FT4, and thyroid-stimulating hormone (TSH) measurements at 1, 2, 4, 6, 8, 10, and 12 months postoperatively, and clinical examination.
RESULTS: Grafts survived and gradually functioned in all patients to a variable extent after a latent period (mean (99m) Tc uptake = 1.28 ± 0.37%). Mean values for FT3, FT4, TSH at 12 months were 1.75 ± 0.48 pg/mL, 1.06 ± 0.26 ng/dL, and 28.08 ± 34.01 μIU/mL respectively.
CONCLUSION: Thyroid autotransplantation restored euthyroid status in 33.3% of patients after 12 months. A role of age, operative time, and (99m) Tc-uptake in determining the final graft outcome is possible.

PMID: 29076198 [PubMed - as supplied by publisher]

from #ENT-PubMed via ola Kala on Inoreader http://ift.tt/2xupYkN