Αρχειοθήκη ιστολογίου

Πέμπτη 7 Δεκεμβρίου 2017

Anti-cytokine autoantibodies in a patient with a heterozygous NFKB2 mutation

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Publication date: Available online 7 December 2017
Source:Journal of Allergy and Clinical Immunology
Author(s): Kesava A. Ramakrishnan, William Rae, Gabriela Barcenas-Morales, Yifang Gao, Reuben J. Pengelly, Sanjay V. Patel, Dinkantha S. Kumararatne, Sarah Ennis, Rainer Döffinger, Saul N. Faust, Anthony P. Williams

Teaser

We report a family with a heterozygous NFKB2 mutation in which anti-cytokine autoantibodies were identified in one individual. Rituximab therapy for autoantibodies led to a reduction in anti-cytokine autoantibodies and a marked improvement in infectious susceptibility.


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