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Κυριακή 4 Φεβρουαρίου 2018

Mutual inhibition of lateral inhibition: a network motif for an elementary computation in the brain

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Publication date: April 2018
Source:Current Opinion in Neurobiology, Volume 49
Author(s): Minoru Koyama, Avinash Pujala
A series of classical studies in non-human primates has revealed the neuronal activity patterns underlying decision-making. However, the circuit mechanisms for such patterns remain largely unknown. Recent detailed circuit analyses in simpler neural systems have started to reveal the connectivity patterns underlying analogous processes. Here we review a few of these systems that share a particular connectivity pattern, namely mutual inhibition of lateral inhibition. Close examination of these systems suggests that this recurring connectivity pattern ('network motif') is a building block to enforce particular dynamics, which can be used not only for simple behavioral choice but also for more complex choices and other brain functions. Thus, a network motif provides an elementary computation that is not specific to a particular brain function and serves as an elementary building block in the brain.



from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/2s5GjhB

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