Association of post-traumatic stress symptom severity with Health-related Quality of Life and self-reported functioning across 12-months after Severe Traumatic Brain Injury

Publication date: Available online 12 March 2018
Source:Archives of Physical Medicine and Rehabilitation
Author(s): Colin M. Bosma, Nashwa Mansoor, Chiara S. Haller
ObjectiveThe present study investigated the relationship between Post-traumatic stress (PTS) symptom severity and Health-related Quality of Life (HRQoL) after severe Traumatic Brain Injury (TBI).DesignLongitudinal prospective multi-center, cohort study on severe TBI in Switzerland (2007-2011). Injury severity was determined using the Abbreviated Injury Score of the Head region (HAIS), following clinical assessment and initial computed tomography (CT).SettingBaseline data was gathered at time/location of the accident. Longitudinal assessments were done at 3, 6, and 12 months post-injury at the hospital, the rehabilitation unit, and/or the patients living facility.ParticipantsA total of 109 patients with severe TBI were included in the analyses.InterventionsNot applicable.Main Outcome Measurea) HRQoL (SF-12, physical and mental component scales, respectively), b) Self-reported emotional, cognitive, and interpersonal functioning (Patient Competency Rating Scale for Neuro-Rehabilitation [PCRS-NR]).ResultsMultilevel models for patients age >50 and ≤50 respectively, revealed significant negative associations between PTS symptom severity and interpersonal functioning (p≤50 = .002; p>50 = <.001). Among patients ≤ 50 years, PTS symptom severity was significantly associated with total functioning (p = .001) and emotional functioning (p = .0006). Among all patients, PTS symptom severity was significantly associated with cognitive functioning (p = <.001) and mental HRQoL (p = .01).ConclusionFindings indicate that PTS symptoms after severe TBI are negatively associated with HRQoL and emotional, cognitive, and interpersonal functioning.



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