Preserved somatosensory discrimination predicts consciousness recovery in unresponsive wakefulness syndrome

Unresponsive Wakefulness Syndrome (UWS) is a disorder of consciousness (DOC) characterized by spontaneous eye opening in the absence of consistent behavioral responses to external stimuli. When reproducible verbal or motor signs of awareness are detected, the clinical condition is defined as Minimally Conscious State (MCS). In clinical practice, different bedside assessment tools are used to detect purposeful behavior and discriminate between DOCs. Among them, the Coma Recovery Scale-Revised (CRS-R, Kalmar and Giacino, 2005) is considered the most sensitive tool.

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