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Σάββατο 5 Αυγούστου 2017

Reduced immunoglobulin gene diversity in patients with Cornelia de Lange syndrome

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Publication date: Available online 5 August 2017
Source:Journal of Allergy and Clinical Immunology
Author(s): Andrea Björkman, Likun Du, Mirjam van der Burg, Valerie Cormier-Daire, Guntram Borck, Juan Pié, Britt-Marie Anderlid, Lennart Hammarström, Lena Ström, Jean-Pierre de Villartay, David Kipling, Deborah Dunn Walters, Qiang Pan-Hammarström

Teaser

Altered IGH repertoires with reduced diversity, skewed VH gene usage and reduced frequency of somatic hypermutation were observed in CdLS patients.


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