Temporal Response of Angiogenesis and Hypertrophy to Resistance Training in Young Men.

While endurance exercise training promotes angiogenesis and improves metabolic health, the effect of resistance training on this process is less well defined. We hypothesised that capillarization would increase proportionally, and concurrently, with muscle fiber hypertrophy in response to resistance training in young men. Methods: In this double blind, randomized control trial, 36 males (22 +/- 1 y) were randomized to placebo or protein supplementation, and participated in 12-wk of resistance training. Skeletal muscle biopsies were collected prior to, and following 2, 4, 8, and 12-wk of training. Immunohistochemistry assessed fiber-type specific size and capillarization. Western blot and RT-PCR assessed proteins involved in the molecular regulation of angiogenesis. Results: Resistance training effectively increased type I (15 +/- 4%; P

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