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Παρασκευή 23 Φεβρουαρίου 2018

Explanted Vascular and Endovascular Graft Analysis: Where Do We Stand and What Should We Do?

Publication date: Available online 23 February 2018
Source:European Journal of Vascular and Endovascular Surgery
Author(s): Anne Lejay, Benjamin Colvard, Louis Magnus, Delphine Dion, Yannick Georg, Julie Papillon, Fabien Thaveau, Bernard Geny, Lee Swanström, Fréderic Heim, Nabil Chakfé
Objective/BackgroundSince the late 1950s, major advances in vascular surgical practice have been closely associated with the introduction of novel vascular implants. These devices have been constructed from a variety of materials and have been designed to be implanted in several different ways. Despite a rigorous regulatory process, regular failures continue to be observed. A systematic review of the literature and of the Geprovas registry was performed in order to improve understanding of the failures.MethodsA systematic review was performed via a search of the MEDLINE and Embase databases. Full text, English, German, or French language studies without any chronological limit were included. The reference lists of included studies, as well as the first 20 related items, were scanned for other potentially relevant studies.ResultsData extraction allowed the evaluation of 184 publications; 72 publications met the inclusion criteria. Only 12 publications reported sufficient data for structural, histopathological, and epidemiological analysis. However, explant analysis allowed the understanding of degenerative phenomena: "warp knitted" replaced "weft knitted" polyethylene terephthalate grafts, decreasing the risk of dilatation or rupture; inter-nodal distance was modified in order to improve polytetrafluoroethylene graft incorporation capacities; and index of saturation, endograft fabric/stent interactions, and stent fatigue phenomena have been extensively studied in an attempt to improve endovascular device durability.ConclusionA general lack of depth of reporting of explants remains. Dedicated systematic explant analysis programs are the key to improving the performance of future generations of devices.



from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/2BKhWsS

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