Development of a New Patient-reported Outcome Instrument to Evaluate Treatments for Scars: The SCAR-Q

Background: Every year millions of individuals acquire scars. A literature review of patient-reported outcome (PRO) instruments identified content limitations in existing scar-specific measures. The aim of this study was to develop a new PRO instrument called SCAR-Q for children and adults with surgical, traumatic, and burn scars. Methods: We performed a secondary analysis of the qualitative datasets used in the development of PRO instruments for plastic and reconstructive surgery, that is, BREAST-Q, FACE-Q, BODY-Q, and CLEFT-Q. The keyword "scar*" was used to extract scar-specific text. Data were analyzed to identify concepts of interest and to form a comprehensive item pool. Scales were developed and refined through multiple rounds of cognitive interviews with patients and with input from international clinical experts between July 2015 and December 2016. Results: A total of 52 children and 192 adults from the qualitative datasets provided between 1 and 34 scar-specific codes (n = 1,227). The analysis led to the identification of 3 key domains for which scales were developed: scar appearance (eg, size, color, contour), scar symptoms (eg, painful, tight, itchy), and psychosocial impact (eg, feeling self-conscious, bothered by scar). Cognitive interviews with 25 adults and 20 pediatric participants with scars, plus feedback from 27 clinical experts, led to rewording and removal of items, and new items added. These steps ensured content validity for SCAR-Q in a broad range of scars. Conclusions: The SCAR-Q is now being field-tested. Once completed, we anticipate SCAR-Q will be used in clinical practice and in clinical trials to test different scar therapies. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. Published online 24 April 2018. Received for publication November 21, 2017; accepted December 13, 2017. Disclosure: SCAR-Q is owned by Memorial Sloan-Kettering Cancer Center and McMaster University. Drs Klassen and Pusic are co-developers of the SCAR-Q and, as such, could potentially receive a share of any license revenues as royalties based on their institutions inventor sharing policy. The authors have no financial interest to declare in relation to the content of this article. The Article Processing Charge was paid for from the Memorial Sloan-Kettering Cancer Center Philanthropy Research Fund. Anne F Klassen, DPhil, Department of Pediatrics, McMaster University, 1280 Main Street W, Hamilton, Ontario, L8S 4L8, Canada, E-mail: aklass@mcmaster.ca Copyright © 2018 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the American Society of Plastic Surgeons. All rights reserved.

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