Cancers, Vol. 12, Pages 2548: Cytochrome C Oxidase Subunit 4 (COX4): A Potential Therapeutic Target for the Treatment of Medullary Thyroid Cancer Cancers doi: 10.3390/cancers12092548 Authors: Athanasios Bikas Kirk Jensen Aneeta Patel John Costello Sarah M. Reynolds Maria Cecilia Mendonca-Torres Shilpa Thakur Joanna Klubo-Gwiezdzinska Dorina Ylli Leonard Wartofsky Kenneth Burman Vasyl Vasko The nuclear-encoded subunit 4 of cytochrome c oxidase (COX4) plays...
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Cancers, Vol. 12, Pages 2547: Occupational and Environmental Carcinogenesis Cancers doi: 10.3390/cancers12092547 Authors: Caterina Ledda Venerando Rapisarda Occupational carcinogens have been shown to cause a considerable disease burden at a national and global level [...]
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Cancers, Vol. 12, Pages 2546: CCAAT/Enhancer-Binding Protein Delta (C/EBPδ): A Previously Unrecognized Tumor Suppressor That Limits the Oncogenic Potential of Pancreatic Ductal Adenocarcinoma Cells Cancers doi: 10.3390/cancers12092546 Authors: Leonie Hartl JanWillem Duitman Hella L. Aberson Kan Chen Frederike Dijk Joris J.T.H. Roelofs Mark P.G. Dings Gerrit K.J. Hooijer Pratika Y. Hernanda Qiunwei Pan Olivier R. Busch Marc G.H. Besselink Ton Boerman Maikel...
Mon Sep 07, 2020 03:00
Cancers, Vol. 12, Pages 2545: FANCD2 Confers a Malignant Phenotype in Esophageal Squamous Cell Carcinoma by Regulating Cell Cycle Progression Cancers doi: 10.3390/cancers12092545 Authors: Lisa Chan Lei Valen Zhuoyou Yu Josephine Mun Yee Ko Lvwen Ning Maria Li Lung Fanconi anemia patients with germline genetic defects in FANCD2 are highly susceptible to cancers. Esophageal squamous cell carcinoma (ESCC) is a deadly cancer. Little is known about the function of FANCD2 in ESCC....
Mon Sep 07, 2020 03:00
Cancers, Vol. 12, Pages 2540: Non-Hematologic Toxicity of Bortezomib in Multiple Myeloma: The Neuromuscular and Cardiovascular Adverse Effects Cancers doi: 10.3390/cancers12092540 Authors: Elia Pancheri Valeria Guglielmi Grzegorz M. Wilczynski Manuela Malatesta Paola Tonin Giuliano Tomelleri Dominika Nowis Gaetano Vattemi The overall approach to the treatment of multiple myeloma (MM) has undergone several changes during the past decade. and proteasome inhibitors...
Mon Sep 07, 2020 03:00
Cancers, Vol. 12, Pages 2543: CeRNA Network Analysis Representing Characteristics of Different Tumor Environments Based on 1p/19q Codeletion in Oligodendrogliomas Cancers doi: 10.3390/cancers12092543 Authors: Ju Won Ahn YoungJoon Park Su Jung Kang So Jung Hwang Kyung Gi Cho JaeJoon Lim KyuBum Kwack Oligodendroglioma (OD) is a subtype of glioma occurring in the central nervous system. The 1p/19q codeletion is a prognostic marker of OD with an isocitrate dehydrogenase...
Mon Sep 07, 2020 03:00
Cancers, Vol. 12, Pages 2544: Latest Development in Multiple Myeloma Cancers doi: 10.3390/cancers12092544 Authors: Yoichi Imai Specialists in the field of multiple myeloma (MM) research have written a series of 12 articles (2 original articles, 10 reviews) in the Special Issue “Latest Development in Multiple Myeloma” [...]
Mon Sep 07, 2020 03:00
Cancers, Vol. 12, Pages 2541: Combination Treatment with GSK126 and Pomalidomide Induces B-Cell Differentiation in EZH2 Gain-of-Function Mutant Diffuse Large B-Cell Lymphoma Cancers doi: 10.3390/cancers12092541 Authors: Sungryul Park Seung-Hyun Jo Jong-Hwan Kim Seon-Young Kim Jae Du Ha Jong Yeon Hwang Myeong Youl Lee Jong Soon Kang Tae-Su Han Sung Goo Park Sunhong Kim Byoung Chul Park Jeong-Hoon Kim Enhancer of zeste 2 polycomb repressive complex 2...
Mon Sep 07, 2020 03:00
Cancers, Vol. 12, Pages 2542: Neurotrophin Signaling in Medulloblastoma Cancers doi: 10.3390/cancers12092542 Authors: Amanda Thomaz Mariane Jaeger Algemir L. Brunetto André T. Brunetto Lauro Gregianin Caroline Brunetto de Farias Vijay Ramaswamy Carolina Nör Michael D. Taylor Rafael Roesler Neurotrophins are a family of secreted proteins that act by binding to tropomyosin receptor kinase (Trk) or p75NTR receptors to regulate nervous system development and plasticity....
Mon Sep 07, 2020 03:00
Cancers, Vol. 12, Pages 2538: Orbital and Eyelid B-Cell Lymphoma: A Multicenter Retrospective Study Cancers doi: 10.3390/cancers12092538 Authors: Gustavo Savino Giulia Midena Maria Antonietta Blasi Remo Battendieri Gabriela Grimaldi Martina Maceroni Fausto Tranfa Pasquale Napolitano Vittoria Lanni Adriana Iuliano Background: The aim of this study was to analyze patients diagnosed, staged and treated for orbital and eyelid B-cell lymphoma (OEL). Methods: One...
Mon Sep 07, 2020 03:00
Cancers, Vol. 12, Pages 2535: Tamoxifen and Endometrial Cancer: A Janus-Headed Drug Cancers doi: 10.3390/cancers12092535 Authors: Günter Emons Alexander Mustea Clemens Tempfer Tamoxifen is a selective estrogen receptor modulator used for the treatment and prevention of estrogen receptor (ER)—positive breast cancer. However, tamoxifen increases the risk of endometrial cancer (EC) by about 2–7 fold, and more aggressive types of EC with poor prognoses are observed...
Mon Sep 07, 2020 03:00
Cancers, Vol. 12, Pages 2539: RASAL1 and ROS1 Gene Variants in Hereditary Breast Cancer Cancers doi: 10.3390/cancers12092539 Authors: Federica Isidori Isotta Bozzarelli Simona Ferrari Lea Godino Giovanni Innella Daniela Turchetti Elena Bonora Breast cancer (BC) is the second leading cause of death in women. BC patients with family history or clinical features suggestive of inherited predisposition are candidate to genetic testing to determine whether a hereditary cancer...
Mon Sep 07, 2020 03:00
Cancers, Vol. 12, Pages 2536: Retrospective Analysis of Patients with Signet Ring Subtype of Colorectal Cancer with Peritoneal Metastasis Treated with CRS & HIPEC Cancers doi: 10.3390/cancers12092536 Authors: Aruna Prabhu Andreas Brandl Satoshi Wakama Shouzou Sako Haruaki Ishibashi Akiyoshi Mizumoto Nobuyuki Takao Kousuke Noguchi Shunsuke Motoi Masumi Ichinose Yang Liu Yutaka Yonemura Signet ring cell subtype (SRC) of colorectal cancer (CRC) is a...
Mon Sep 07, 2020 03:00
Cancers, Vol. 12, Pages 2537: Spatial Distribution of Focal Lesions in Whole-Body MRI and Influence of MRI Protocol on Staging in Patients with Smoldering Multiple Myeloma According to the New SLiM-CRAB-Criteria Cancers doi: 10.3390/cancers12092537 Authors: Markus Wennmann Thomas Hielscher Laurent Kintzelé Bjoern H. Menze Georg Langs Maximilian Merz Sandra Sauer Hans-Ulrich Kauczor Heinz-Peter Schlemmer Stefan Delorme Hartmut Goldschmidt Niels Weinhold Jens...
Mon Sep 07, 2020 03:00
Cancers, Vol. 12, Pages 2534: Therapeutically Significant MicroRNAs in Primary and Metastatic Brain Malignancies Cancers doi: 10.3390/cancers12092534 Authors: Akilandeswari A. Balachandran Leon M. Larcher Suxiang Chen Rakesh N. Veedu Brain cancer is one among the rare cancers with high mortality rate that affects both children and adults. The most aggressive form of primary brain tumor is glioblastoma. Secondary brain tumors most commonly metastasize from primary cancers of...
Mon Sep 07, 2020 03:00
Cells, Vol. 9, Pages 2041: Eosinophils and Neutrophils—Molecular Differences Revealed by Spontaneous Raman, CARS and Fluorescence Microscopy Cells doi: 10.3390/cells9092041 Authors: Aleksandra Dorosz Marek Grosicki Jakub Dybas Ewelina Matuszyk Marko Rodewald Tobias Meyer Jürgen Popp Kamilla Malek Malgorzata Baranska Leukocytes are a part of the immune system that plays an important role in the host’s defense against viral, bacterial, and fungal infections....
Mon Sep 07, 2020 03:00
Cells, Vol. 9, Pages 2042: “Repair Me if You Can”: Membrane Damage, Response, and Control from the Viral Perspective Cells doi: 10.3390/cells9092042 Authors: Coralie F. Daussy Harald Wodrich Cells are constantly challenged by pathogens (bacteria, virus, and fungi), and protein aggregates or chemicals, which can provoke membrane damage at the plasma membrane or within the endo-lysosomal compartments. Detection of endo-lysosomal rupture depends on a family of sugar-binding lectins,...
Mon Sep 07, 2020 03:00
Cells, Vol. 9, Pages 2043: Cellular Uptake of siRNA-Loaded Nanocarriers to Knockdown PD-L1: Strategies to Improve T-cell Functions Cells doi: 10.3390/cells9092043 Authors: Raweewan Thiramanas Mengyi Li Shuai Jiang Katharina Landfester Volker Mailänder T-cells are a type of lymphocyte (a subtype of white blood cells) that play a central role in cell-mediated immunity. Currently, adoptive T-cell immunotherapy is being developed to destroy cancer cells. In this therapy, T-cells...
Mon Sep 07, 2020 03:00
Cells, Vol. 9, Pages 2044: Decoding IL-23 Signaling Cascade for New Therapeutic Opportunities Cells doi: 10.3390/cells9092044 Authors: Gloria Pastor-Fernández Isabel R. Mariblanca María N. Navarro The interleukin 23 (IL-23) is a key pro-inflammatory cytokine in the development of chronic inflammatory diseases, such as psoriasis, inflammatory bowel diseases, multiple sclerosis, or rheumatoid arthritis. The pathological consequences of excessive IL-23 signaling have been linked to...
Mon Sep 07, 2020 03:00
Challenges, Vol. 11, Pages 20: Report on Digital Literacy in Academic Meetings during the 2020 COVID-19 Lockdown Challenges doi: 10.3390/challe11020020 Authors: Carol Nash COVID-19, a novel coronavirus, was deemed a pandemic during mid-March 2020. In response, lockdowns were imposed for an indefinite period world-wide. Academic institutions were no exception. Continuing meetings of academic groups consequently necessitated online communication. Various platforms were available from which...
Mon Sep 07, 2020 03:00
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