Saliva with reduced calcium and phosphorous concentrations: Effect on erosion dental lesions

Abstract

Objectives

To investigate whether saliva formulations with reduced calcium (Ca) and inorganic phosphorous (Pi) concentration would affect dental erosion caused by hydrochloric acid (HCl).

Methods

Enamel and root dentine bovine slabs were embedded, polished and measured for surface Knoop microhardness (SMH). After reference areas were created, specimens were exposed to HCl solution (0.01M; pH 2; 120s) and immersed in artificial salivas (6h) containing three different Ca/Pi concentrations (n=15), which simulate serum conditions of normo-, mild- or severe hypocalcaemia. The control group was immersed in Ca/Pi-free saliva. The study protocol was carried out 2x/day for 5 days. Surface loss of enamel and root dentine was assessed using an optical profilometer and SMH was remeasured for enamel.

Results

ANOVA (p<0.001) and Tukey's test showed that enamel loss in groups subjected to artificial salivas that simulated mild- or severe hypocalcaemia did not differ from that resembling normocalcemia. %SMH was lower when saliva was mildly- and normally-concentrated in Ca/Pi (p<0.001). Root dentine loss was higher in saliva simulating severe hypocalcaemia than in those referring to mild, hypo- and normocalcemia.

Conclusions

Depending on the dental substrate, salivary formulations resembling serum hypocalcaemia affected surface loss due to erosion and rehardening thereof.

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from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/2slacKW