Antibiotics, Vol. 9, Pages 290: Editorial for the Special Issue: “Targeting β-Lactamases to Fight Bacterial Resistance to β-Lactam Antibiotics” Antibiotics doi: 10.3390/antibiotics9060290 Authors: Pozzi In bacteria, a major resistance mechanism to β-lactam antibiotics is the production of one or more β-lactamase enzymes. β-Lactamases belong to two structurally and mechanistically unrelated families of enzymes, serine-β-lactamases (SBLs; classes A,...
Thu May 28, 2020 03:00
Antibiotics, Vol. 9, Pages 289: Morphological, Chemical, and Genetic Characteristics of Korean Native Thyme Bak-Ri-Hyang (Thymus quinquecostatus Celak.) Antibiotics doi: 10.3390/antibiotics9060289 Authors: Kim Moon Kim Sowndhararajan Bak-ri-hyang (Thymus quinquecostatus Celak.) is an important medicinal and aromatic plant in Korea. T. quinquecostatus population and is always mixed with other thyme cultivars during cultivation and marketing. Hence, this study aimed to determine...
Thu May 28, 2020 03:00
Antibiotics, Vol. 9, Pages 288: Redundant Anaerobic Antimicrobial Prescriptions in German Acute Care Hospitals: Data from a National Point Prevalence Survey Antibiotics doi: 10.3390/antibiotics9060288 Authors: Aghdassi Gastmeier Behnke Hansen Kramer Despite limited indications, redundant anaerobic antimicrobial prescriptions (RAAPs) are frequent. The objective of this study was to assess the prevalence and characteristics of RAAPs in German acute care hospitals. In a...
Thu May 28, 2020 03:00
Antibodies, Vol. 9, Pages 19: Anti-Idiotypic Agonistic Antibodies: Candidates for the Role of Universal Remedy Antibodies doi: 10.3390/antib9020019 Authors: Stanova Ryabkova Utekhin Shoenfeld Churilov Shoenfeld Anti-idiotypic antibodies (anti-IDs) were discovered at the very beginning of the 20th century and have attracted attention of researchers for many years. Nowadays, there are five known types of anti-IDs: α, β, γ, ε,...
Thu May 28, 2020 03:00
Atmosphere, Vol. 11, Pages 564: Definition of an Emission Factor for VOC Emitted from Italian and European Refineries Atmosphere doi: 10.3390/atmos11060564 Authors: Roveda Polvara Invernizzi Capelli Sironi Refineries are a major source of atmospheric emissions, which typically include CO, SO2, NOX, particulates, and volatile organic compounds (VOCs). There has been an increasing level of attention toward the emissions of VOCs related to their environmental impact as...
Thu May 28, 2020 03:00
Atmosphere, Vol. 11, Pages 560: Latitude and Topographical Dependence of Lightning Return Stroke Peak Current in Natural and Tower-Initiated Negative Ground Flashes Atmosphere doi: 10.3390/atmos11060560 Authors: Cooray Rubinstein Rachidi Experimental data show that the peak currents of first and subsequent lightning return strokes in negative ground flashes increase with decreasing latitude. In this paper, the reason for this dependence of peak return stroke current on latitude...
Thu May 28, 2020 03:00
Atmosphere, Vol. 11, Pages 563: Regional Transport Increases Ammonia Concentration in Beijing, China
Atmosphere, Vol. 11, Pages 563: Regional Transport Increases Ammonia Concentration in Beijing, China Atmosphere doi: 10.3390/atmos11060563 Authors: Qingmei Wang Yucong Miao Ligang Wang To elucidate the critical factors influencing the ammonia (NH3) concentration in Beijing, this study combined observational analyses, backward trajectory calculations, and meteorology–chemistry coupled simulations to investigate the variations in the NH3 concentration from 11 May to 24...
Thu May 28, 2020 03:00
Atmosphere, Vol. 11, Pages 559: Ecological Assessment of Particulate Material (PM5 and PM10) in Urban Habitats Atmosphere doi: 10.3390/atmos11060559 Authors: Simon Molnár Tóthmérész Szabó Trees are especially useful biological indicators. We tested the suitability of tree leaves (Common Lime) to assess PM5 and PM10 deposition in the three summer months of 2018 in Debrecen city, Hungary. We also tested the usefulness of the cheap and simple gravimetric method to assess the...
Thu May 28, 2020 03:00
Atmosphere, Vol. 11, Pages 561: Comparison of Two Models to Estimate Deposition of Fungi and Bacteria in the Human Respiratory Tract Atmosphere doi: 10.3390/atmos11060561 Authors: Sagona Secondo Mainelis Understanding the deposition of bioaerosols in the respiratory system may help determine the risk of disease; however, measuring deposition fraction in-situ is difficult. Computational models provide estimates of particle deposition fraction for given breathing and particle...
Thu May 28, 2020 03:00
Atmosphere, Vol. 11, Pages 562: Characteristics of Raindrop Size Distribution on the Eastern Slope of the Tibetan Plateau in Summer Atmosphere doi: 10.3390/atmos11060562 Authors: Wang Zheng Cheng Wang Precipitation microphysics over the Tibetan Plateau (TP) remain insufficiently understood, due to the lack of observations and studies. This paper presents a comprehensive investigation of the raindrop size distribution (DSD) for rainfall that happened on the eastern slope...
Thu May 28, 2020 03:00
Behavioral Sciences, Vol. 10, Pages 95: The Value of Dignity in Prison: A Qualitative Study with Life Convicts Behavioral Sciences doi: 10.3390/bs10060095 Authors: Testoni Marrella Biancalani Cottone Alemanno Mamo Grassi Background: This research is based on the perspective of dignity according to Chochinov; thus, the life imprisonment of detainees is assimilated to a severe disease. Methods: Ten male prisoners were interviewed trough Chochinov’s Dignity...
Thu May 28, 2020 03:00
Biomedicines, Vol. 8, Pages 137: Endocrine-Disrupting Chemicals and Insulin Resistance in Children Biomedicines doi: 10.3390/biomedicines8060137 Authors: Rotondo Chiarelli The purpose of this article is to review the evidence linking background exposure to endocrine-disrupting chemicals (EDCs) with insulin resistance in children. Although evidence in children is scarce since very few prospective studies exist even in adults, evidence that EDCs might be involved in the development...
Thu May 28, 2020 03:00
Biomolecules, Vol. 10, Pages 828: Heparin Blocks the Inhibition of Tissue Kallikrein 1 by Kallistatin through Electrostatic Repulsion Biomolecules doi: 10.3390/biom10060828 Authors: Lina Ma Jiawei Wu Ying Zheng Zimei Shu Zhenquan Wei Yinbiao Sun Robin W. Carrell Aiwu Zhou Kallistatin, also known as SERPINA4, has been implicated in the regulation of blood pressure and angiogenesis, due to its specific inhibition of tissue kallikrein 1 (KLK1) and/or by its heparin...
Thu May 28, 2020 03:00
Biomolecules, Vol. 10, Pages 825: Hamp Type-1 Promotes Antimicrobial Defense via Direct Microbial Killing and Regulating Iron Metabolism in Grass Carp (Ctenopharyngodon idella) Biomolecules doi: 10.3390/biom10060825 Authors: Yazhen Hu Tomofumi Kurobe Xiaoling Liu Yong-An Zhang Jianguo Su Gailing Yuan Hepcidin is an antimicrobial peptide and regulator of iron homeostasis which has two isoforms in most fishes and some mammals. Previous studies have reported that the two...
Thu May 28, 2020 03:00
Biomolecules, Vol. 10, Pages 826: Activation of 3-Mercaptopyruvate Sulfurtransferase by Glutaredoxin Reducing System Biomolecules doi: 10.3390/biom10060826 Authors: Noriyuki Nagahara Glutaredoxin (EC 1.15–1.21) is known as an oxidoreductase that protects cysteine residues within proteins against oxidative stress. Glutaredoxin catalyzes an electron transfer reaction that donates an electron to substrate proteins in the reducing system composed of glutaredoxin, glutathione, glutathione...
Thu May 28, 2020 03:00
Biomolecules, Vol. 10, Pages 827: AP-TSS: A New Method for the Analysis of RNA Expression from Particular and Challenging Transcription Start Sites Biomolecules doi: 10.3390/biom10060827 Authors: Gabriel Le Berre Virginie Hossard Jean-Francois Riou Anne-Laure Guieysse-Peugeot Alternative promoter usage involved in the regulation of transcription, splicing, and translation contributes to proteome diversity and is involved in a large number of diseases, in particular, cancer....
Thu May 28, 2020 03:00
Biosensors, Vol. 10, Pages 56: Wearable Skin Sensors and Their Challenges: A Review of Transdermal, Optical, and Mechanical Sensors Biosensors doi: 10.3390/bios10060056 Authors: Ammar Ahmad Tarar Umair Mohammad Soumya K. Srivastava Wearable technology and mobile healthcare systems are both increasingly popular solutions to traditional healthcare due to their ease of implementation and cost-effectiveness for remote health monitoring. Recent advances in research, especially the miniaturization...
Thu May 28, 2020 03:00
Brain Sciences, Vol. 10, Pages 329: Cortical Thickness and Natural Scene Recognition in the Child’s Brain Brain Sciences doi: 10.3390/brainsci10060329 Authors: François Orliac Grégoire Borst Grégory Simon Katell Mevel Julie Vidal Sonia Dollfus Olivier Houdé Carole Peyrin Nicolas Poirel Visual scenes are processed in terms of spatial frequencies. Low spatial frequencies (LSF) carry coarse information, whereas high spatial frequencies (HSF) subsequently carry information...
Thu May 28, 2020 03:00
Brain Sciences, Vol. 10, Pages 327: The Influence of Sleep Quality, Vigilance, and Sleepiness on Driving-Related Cognitive Abilities: A Comparison between Young and Older Adults Brain Sciences doi: 10.3390/brainsci10060327 Authors: Chiara Bartolacci Serena Scarpelli Aurora D’Atri Maurizio Gorgoni Ludovica Annarumma Chiara Cloos Anna Maria Giannini Luigi De Gennaro Background: Driving performance is strongly vulnerable to drowsiness and vigilance fluctuations. Excessive...
Thu May 28, 2020 03:00
Brain Sciences, Vol. 10, Pages 328: Neural Correlates of Modality-Sensitive Deviance Detection in the Audiovisual Oddball Paradigm Brain Sciences doi: 10.3390/brainsci10060328 Authors: Melissa Randazzo Ryan Priefer Paul J. Smith Amanda Nagler Trey Avery Karen Froud The McGurk effect, an incongruent pairing of visual /ga/–acoustic /ba/, creates a fusion illusion /da/ and is the cornerstone of research in audiovisual speech perception. Combination illusions occur...
Thu May 28, 2020 03:00
Cancers, Vol. 12, Pages 1395: Adrenocortical Carcinoma and CT Assessment of Therapy Response: The Value of Combining Multiple Criteria Cancers doi: 10.3390/cancers12061395 Authors: Roberta Ambrosini Maria Carolina Balli Marta Laganà Martina Bertuletti Luca Bottoni Filippo Vaccher Deborah Cosentini Marco Di Di Terlizzi Sandra Sigala Salvatore Grisanti Guido Alberto Massimo Tiberio Alfredo Berruti Luigi Grazioli We evaluated tumor response at Computed...
Thu May 28, 2020 03:00
Cancers, Vol. 12, Pages 1396: Mechanisms of B Cell Receptor Activation and Responses to B Cell Receptor Inhibitors in B Cell Malignancies Cancers doi: 10.3390/cancers12061396 Authors: Dimitar G. Efremov Sven Turkalj Luca Laurenti The B cell receptor (BCR) pathway has been identified as a potential therapeutic target in a number of common B cell malignancies, including chronic lymphocytic leukemia, diffuse large B cell lymphoma, Burkitt lymphoma, follicular lymphoma, mantle cell...
Thu May 28, 2020 03:00
Cancers, Vol. 12, Pages 1393: Anti-EGFR Therapy Induces EGF Secretion by Cancer-Associated Fibroblasts to Confer Colorectal Cancer Chemoresistance Cancers doi: 10.3390/cancers12061393 Authors: Colleen M. Garvey Roy Lau Alyssa Sanchez Ren X. Sun Emma J. Fong Michael E. Doche Oscar Chen Anthony Jusuf Heinz-Josef Lenz Brent Larson Shannon M. Mumenthaler Targeted agents have improved the efficacy of chemotherapy for cancer patients, however, there remains a...
Thu May 28, 2020 03:00
Cancers, Vol. 12, Pages 1392: Correction: Teeuwssen and Fodde; Colon Cancer Heterogeneity and Phenotypic Plasticity in Metastasis Formation. Cancers 2019, 11(9), 1368 Cancers doi: 10.3390/cancers12061392 Authors: Teeuwssen Fodde The authors would like to make a correction to their published paper [...]
Thu May 28, 2020 03:00
Cancers, Vol. 12, Pages 1391: Heterogenous Effect of Risk Factors on Breast Cancer across the Breast Density Categories in a Korean Screening Population Cancers doi: 10.3390/cancers12061391 Authors: Boyoung Park Se-Eun Lim HyoJin Ahn Junghyun Yoon Yun Su Choi We evaluated the heterogeneity of the effect of known risk factors on breast cancer development based on breast density by using the Breast Imaging-Reporting and Data System (BI-RADS). In total, 4,898,880 women, aged...
Thu May 28, 2020 03:00
Cancers, Vol. 12, Pages 1394: Choline PET/CT in Multiple Myeloma Cancers doi: 10.3390/cancers12061394 Authors: Charles Mesguich Cyrille Hulin Axelle Lascaux Laurence Bordenave Gerald Marit Elif Hindié The field of multiple myeloma (MM) imaging has evolved. The International Myeloma Working Group recently recommended performing 18F-fluorodeoxyglucose glucose (18FDG) positron emission tomography/computed tomography (PET/CT) with the aim of staging MM patients at baseline...
Thu May 28, 2020 03:00
Cancers, Vol. 12, Pages 1384: FDG-PET/CT, a Promising Exam for Detecting High-Risk Myeloma Patients?
Cancers, Vol. 12, Pages 1384: FDG-PET/CT, a Promising Exam for Detecting High-Risk Myeloma Patients? Cancers doi: 10.3390/cancers12061384 Authors: Anne-Victoire Michaud-Robert Bastien Jamet Clément Bailly Thomas Carlier Philippe Moreau Cyrille Touzeau Mickael Bourgeois Françoise Kraeber-Bodere Caroline Bodet-Milin Multiple myeloma (MM) is a haematological neoplasm characterized by a clonal proliferation of malignant plasma cells in the bone marrow. MM is associated...
Thu May 28, 2020 03:00
Cancers, Vol. 12, Pages 1386: Serum PD-1/PD-L1 Levels, Tumor Expression and PD-L1 Somatic Mutations in HER2-Positive and Triple Negative Normal-Like Feline Mammary Carcinoma Subtypes Cancers doi: 10.3390/cancers12061386 Authors: Catarina Nascimento Ana Catarina Urbano Andreia Gameiro João Ferreira Jorge Correia Fernando Ferreira Tumor microenvironment has gained great relevance due to its ability to regulate distinct checkpoints mediators, orchestrating tumor progression....
Thu May 28, 2020 03:00
Cancers, Vol. 12, Pages 1389: Enhancing the Efficacy of CAR T Cells in the Tumor Microenvironment of Pancreatic Cancer Cancers doi: 10.3390/cancers12061389 Authors: Janina Henze Frank Tacke Olaf Hardt Frauke Alves Wa’el Al Al Rawashdeh Pancreatic cancer has the worst prognosis and lowest survival rate among all types of cancers and thus, there exists a strong need for novel therapeutic strategies. Chimeric antigen receptor (CAR)-modified T cells present a new potential option...
Thu May 28, 2020 03:00
Cancers, Vol. 12, Pages 1382: The Combination of Loss of ALDH1L1 Function and Phenformin Treatment Decreases Tumor Growth in KRAS-Driven Lung Cancer Cancers doi: 10.3390/cancers12061382 Authors: Seon-Hyeong Lee Yoon Jeon Joon Hee Kang Hyonchol Jang Ho Lee Soo-Youl Kim Lung adenocarcinoma cells express high levels of ALDH1L1, an enzyme of the one-carbon pathway that catalyzes the conversion of 10-formyltetrahydrofolate into tetrahydrofolate and NAD(P)H. In this study, we...
Thu May 28, 2020 03:00
Cancers, Vol. 12, Pages 1388: Inhibition of ATM Increases the Radiosensitivity of Uveal Melanoma Cells to Photons and Protons Cancers doi: 10.3390/cancers12061388 Authors: Rumana N. Hussain Sarah E. Coupland Jakub Khzouz Helen Kalirai Jason L. Parsons Treatment of uveal melanoma (UM) is generally successful, with local primary tumour control being at 90%–95%. Localized radiotherapy in the form of plaque brachytherapy or proton beam radiotherapy is the most common...
Thu May 28, 2020 03:00
Cancers, Vol. 12, Pages 1385: Assessment of Periprostatic and Subcutaneous Adipose Tissue Lipolysis and Adipocyte Size from Men with Localized Prostate Cancer Cancers doi: 10.3390/cancers12061385 Authors: Dushan Miladinovic Thomas Cusick Kate L. Mahon Anne-Maree Haynes Colin H. Cortie Barbara J. Meyer Phillip D. Stricker Gary A. Wittert Lisa M. Butler Lisa G. Horvath Andrew J. Hoy The prostate is surrounded by periprostatic adipose tissue (PPAT), the thickness...
Thu May 28, 2020 03:00
Cancers, Vol. 12, Pages 1387: Radiomics Applications in Renal Tumor Assessment: A Comprehensive Review of the Literature Cancers doi: 10.3390/cancers12061387 Authors: Rodrigo Suarez-Ibarrola Mario Basulto-Martinez Alexander Heinze Christian Gratzke Arkadiusz Miernik Radiomics texture analysis offers objective image information that could otherwise not be obtained by radiologists′ subjective radiological interpretation. We investigated radiomics applications in renal...
Thu May 28, 2020 03:00
Cancers, Vol. 12, Pages 1383: Eotaxins and Their Receptor in Colorectal Cancer—A Literature Review Cancers doi: 10.3390/cancers12061383 Authors: Monika Zajkowska Barbara Mroczko Colorectal cancer (CRC) is one of the most common malignancies in the world, with a global incidence of almost 2 million new cases every year. Despite the availability of many diagnostic tests, including laboratory tests and molecular diagnostics, an increasing number of new cases is observed. Thus, it is...
Thu May 28, 2020 03:00
Cancers, Vol. 12, Pages 1381: Hallmarks of Splicing Defects in Cancer: Clinical Applications in the Era of Personalized Medicine Cancers doi: 10.3390/cancers12061381 Authors: Mohammad Alinoor Rahman Farhana Nasrin Sonali Bhattacharjee Saikat Nandi Alternative splicing promotes proteome diversity by using limited number of genes, a key control point of gene expression. Splicing is carried out by large macromolecular machineries, called spliceosome, composed of small RNAs and...
Thu May 28, 2020 03:00
Cancers, Vol. 12, Pages 1390: Role of Collagen Fiber Morphology on Ovarian Cancer Cell Migration Using Image-Based Models of the Extracellular Matrix Cancers doi: 10.3390/cancers12061390 Authors: Samuel Alkmin Rebecca Brodziski Haleigh Simon Daniel Hinton Randall H. Goldsmith Manish Patankar Paul J. Campagnola Remodeling of the extracellular matrix (ECM) is an important part in the development and progression of many epithelial cancers. However, the biological significance...
Thu May 28, 2020 03:00
Cells, Vol. 9, Pages 1344: Migration Inhibitory Factor in Conditioned Medium from Human Umbilical Cord Blood-Derived Mesenchymal Stromal Cells Stimulates Hair Growth Cells doi: 10.3390/cells9061344 Authors: Hyun Ah Oh Jihye Kwak Beom Joon Kim Hye Jin Jin Won Seok Park Soo Jin Choi Wonil Oh Soyoun Um Conventional therapeutic applications of mesenchymal stromal cells (MSCs) focus on cell replacement and differentiation; however, increasing evidence suggests that most...
Thu May 28, 2020 03:00
Cells, Vol. 9, Pages 1346: Deletion of Perilipin 5 Protects Against Hepatic Injury in Nonalcoholic Fatty Liver Disease via Missing Inflammasome Activation Cells doi: 10.3390/cells9061346 Authors: Anastasia Asimakopoulou Kathrin M. Engel Nikolaus Gassler Thilo Bracht Barbara Sitek Eva M. Buhl Stavroula Kalampoka Manuela Pinoé-Schmidt Josef van van Helden Jürgen Schiller Ralf Weiskirchen Nonalcoholic fatty liver disease (NAFLD) is a leading cause of chronic...
Thu May 28, 2020 03:00
Cells, Vol. 9, Pages 1347: Multiple Functions of Fubp1 in Cell Cycle Progression and Cell Survival Cells doi: 10.3390/cells9061347 Authors: Mingyu Kang Hyeon Ji Kim Tae-Jun Kim Jin-Seok Byun Jae-Ho Lee Deok Heon Lee Wanil Kim Do-Yeon Kim The discovery of novel and critical genes implicated in malignant development is a topic of high interest in cancer research. Intriguingly, a group of genes named “double-agent” genes were reported to have both oncogenic...
Thu May 28, 2020 03:00
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