IJMS, Vol. 21, Pages 3829: An Evidence-Based Update on the Molecular Mechanisms Underlying Periodontal Diseases International Journal of Molecular Sciences doi: 10.3390/ijms21113829 Authors: Syed Saad B. Qasim Dalal Al-Otaibi Reham Al-Jasser Sarhang S. Gul Muhammad Sohail Zafar Several investigators have reported about the intricate molecular mechanism underlying periodontal diseases (PD). Nevertheless, the role of specific genes, cells, or cellular mechanisms involved in...
Thu May 28, 2020 03:00
IJMS, Vol. 21, Pages 3830: Mitochondrial Ceramide Effects on the Retinal Pigment Epithelium in Diabetes International Journal of Molecular Sciences doi: 10.3390/ijms21113830 Authors: Yan Levitsky Sandra S. Hammer Kiera P. Fisher Chao Huang Travan L. Gentles David J. Pegouske Caimin Xi Todd A. Lydic Julia V. Busik Denis A. Proshlyakov Mitochondrial damage in the cells comprising inner (retinal endothelial cells) and outer (retinal pigment epithelium (RPE)) blood–retinal...
Thu May 28, 2020 03:00
IJMS, Vol. 21, Pages 3827: Adhesive Properties of the Hyaluronan Pericellular Coat in Hyaluronan Synthases Overexpressing Mesenchymal Stem Cells International Journal of Molecular Sciences doi: 10.3390/ijms21113827 Authors: Sebastian Reiprich Eva Hofbauer Stefanie Kiderlen Hauke Clausen-Schaumann Wolfgang Böcker Attila Aszódi Veronika Schönitzer Hyaluronan (HA), a natural component of the extracellular matrix, is supposed to have a regulatory function in the stem cell...
Thu May 28, 2020 03:00
IJMS, Vol. 21, Pages 3826: Lipid Raft Destabilization Impairs Mouse TRPA1 Responses to Cold and Bacterial Lipopolysaccharides International Journal of Molecular Sciences doi: 10.3390/ijms21113826 Authors: Startek Talavera The Transient Receptor Potential ankyrin 1 cation channel (TRPA1) is expressed in nociceptive sensory neurons and epithelial cells, where it plays key roles in the detection of noxious stimuli. Recent reports showed that mouse TRPA1 (mTRPA1) localizes in lipid...
Thu May 28, 2020 03:00
IJMS, Vol. 21, Pages 3824: ID1-Mediated BMP Signaling Pathway Potentiates Glucagon-Like Peptide-1 Secretion in Response to Nutrient Replenishment International Journal of Molecular Sciences doi: 10.3390/ijms21113824 Authors: Jae Woong Jeong Minki Kim Jiwoo Lee Hae-Kyung Lee Younhee Ko Hyunkyung Kim Sungsoon Fang Glucagon-like peptide-1 (GLP-1) is a well-known incretin hormone secreted from enteroendocrinal L cells in response to nutrients, such as glucose and dietary...
Thu May 28, 2020 03:00
IJMS, Vol. 21, Pages 3825: Post-Ischemic Renal Fibrosis Progression Is Halted by Delayed Contralateral Nephrectomy: The Involvement of Macrophage Activation International Journal of Molecular Sciences doi: 10.3390/ijms21113825 Authors: Pál Tod Eva Nora Bukosza Beáta Róka Tamás Kaucsár Attila Fintha Tibor Krenács Gábor Szénási Péter Hamar (1) Background: Successful treatment of acute kidney injury (AKI)-induced chronic kidney disease (CKD) is unresolved. We aimed...
Thu May 28, 2020 03:00
IJMS, Vol. 21, Pages 3823: 1,4-Disubstituted 1H-1,2,3-Triazoles for Renal Diseases: Studies of Viability, Anti-Inflammatory, and Antioxidant Activities International Journal of Molecular Sciences doi: 10.3390/ijms21113823 Authors: Ching-Yi Cheng Ashanul Haque Ming-Fa Hsieh Syed Imran Hassan Md. Serajul Haque Faizi Necmi Dege Muhammad S. Khan Inflammation is a hallmark of many metabolic diseases. We previously showed that ferrocene-appended 1H-1,2,3-triazole hybrids...
Thu May 28, 2020 03:00
JCM, Vol. 9, Pages 1639: Current Challenges in Chronic Bronchial Infection in Patients with Chronic Obstructive Pulmonary Disease Journal of Clinical Medicine doi: 10.3390/jcm9061639 Authors: José Luis Lopez-Campos Marc Miravitlles David de la Rosa Carrillo Rafael Cantón Juan Jose Soler-Cataluña Miguel Angel Martinez-Garcia Currently, chronic obstructive pulmonary disease (COPD) patients and their physicians face a number of significant clinical challenges, one of which...
Thu May 28, 2020 03:00
JCM, Vol. 9, Pages 1638: Respiratory Mitochondrial Efficiency and DNA Oxidation in Human Sperm after In Vitro Myo-Inositol Treatment Journal of Clinical Medicine doi: 10.3390/jcm9061638 Authors: Laura Governini Rosetta Ponchia Paolo Giovanni Artini Elena Casarosa Ilaria Marzi Angela Capaldo Alice Luddi Paola Piomboni Semen samples are known to contain abnormal amounts of reactive oxygen species (ROS) and oxygen free radicals; therefore, the identification of antioxidant...
Thu May 28, 2020 03:00
JCM, Vol. 9, Pages 1637: Anatomy of Major Duodenal Papilla Influences ERCP Outcomes and Complication Rates: A Single Center Prospective Study Journal of Clinical Medicine doi: 10.3390/jcm9061637 Authors: Gheorghe G. Balan Mukul Arya Adrian Catinean Vasile Sandru Mihaela Moscalu Gabriel Constantinescu Anca Trifan Gabriela Stefanescu Catalin Victor Sfarti Background: Endoscopic retrograde cholangiopancreatography (ERCP) has been one of the most intensely studied...
Thu May 28, 2020 03:00
JCM, Vol. 9, Pages 1636: Risk Stratification in Hypertrophic Cardiomyopathy. Insights from Genetic Analysis and Cardiopulmonary Exercise Testing Journal of Clinical Medicine doi: 10.3390/jcm9061636 Authors: Damiano Magrì Vittoria Mastromarino Giovanna Gallo Elisabetta Zachara Federica Re Piergiuseppe Agostoni Dario Giordano Speranza Rubattu Maurizio Forte Maria Cotugno Maria Rosaria Torrisi Simona Petrucci Aldo Germani Camilla Savio Antonello Maruotti...
Thu May 28, 2020 03:00
JCM, Vol. 9, Pages 1635: Association between Non-Alcoholic Fatty Liver Disease and Chronic Kidney Disease: A Cross-Sectional Study Journal of Clinical Medicine doi: 10.3390/jcm9061635 Authors: Takemi Akahane Manabu Akahane Tadashi Namisaki Kosuke Kaji Kei Moriya Hideto Kawaratani Hiroaki Takaya Yasuhiko Sawada Naotaka Shimozato Yukihisa Fujinaga Masanori Furukawa Koh Kitagawa Takahiro Ozutsumi Yuki Tsuji Daisuke Kaya Akira Mitoro Hitoshi Yoshiji...
Thu May 28, 2020 03:00
JCM, Vol. 9, Pages 1633: Effectiveness and Safety of Oral Anticoagulants among NVAF Patients with Obesity: Insights from the ARISTOPHANES Study Journal of Clinical Medicine doi: 10.3390/jcm9061633 Authors: Steve Deitelzweig Allison Keshishian Amiee Kang Amol D. Dhamane Xuemei Luo Xiaoyan Li Neeraja Balachander Lisa Rosenblatt Jack Mardekian Xianying Pan Manuela Di Fusco Alessandra B. Garcia Garcia Reeves Huseyin Yuce Gregory Y. H. Lip This ARISTOPHANES...
Thu May 28, 2020 03:00
JCM, Vol. 9, Pages 1634: The Influence of Vaginal Native Tissue Repair (VNTR) on Various Aspects of Quality of Life in Women with Symptomatic Pelvic Organ Prolapse—A Prospective Cohort Study Journal of Clinical Medicine doi: 10.3390/jcm9061634 Authors: Ewa Rechberger Katarzyna Skorupska Tomasz Rechberger Aleksandra Kołodyńska Paweł Miotła Beata Kulik-Rechberger Andrzej Wróbel Pelvic organ prolapse (POP) and the associated functional disorders are a major epidemiological...
Thu May 28, 2020 03:00
JCM, Vol. 9, Pages 1629: Liver Transplant Patients with High Levels of Preoperative Serum Ammonia Are at Increased Risk for Postoperative Acute Kidney Injury: A Retrospective Study Journal of Clinical Medicine doi: 10.3390/jcm9061629 Authors: Yoon Sook Lee Yoon Ji Choi Kyu Hee Park Byeong Seon Park Jung-Min Son Ju Yeon Park Hyun-Su Ri Je Ho Ryu Acute kidney injury (AKI) is one of the most frequent postoperative complications after liver transplantation (LT). Increased...
Thu May 28, 2020 03:00
JCM, Vol. 9, Pages 1632: Prevalence and Comorbidity of Atopic Dermatitis in Children: A Large-Scale Population Study Based on Real-World Data Journal of Clinical Medicine doi: 10.3390/jcm9061632 Authors: Yolanda Gilaberte Juan Blas Pérez-Gilaberte Beatriz Poblador-Plou Kevin Bliek-Bueno Antonio Gimeno-Miguel Alexandra Prados-Torres This study aimed at exploring atopic dermatitis (AD) prevalence in children and exhaustively analyzing their comorbidity. We conducted a descriptive...
Thu May 28, 2020 03:00
JCM, Vol. 9, Pages 1627: UnReal? Investigating the Sense of Reality and Psychotic Symptoms with Virtual Reality Journal of Clinical Medicine doi: 10.3390/jcm9061627 Authors: Gad Drori Paz Bar-Tal Yonatan Stern Yair Zvilichovsky Roy Salomon Distortions of reality, such as hallucinations, are common symptoms of many psychiatric conditions. Accordingly, sense of reality (SoR), the ability to discriminate between true and false perceptions, is a central criterion in the assessment...
Thu May 28, 2020 03:00
JCM, Vol. 9, Pages 1630: Significance of NT-proBNP and High-sensitivity Troponin in Friedreich Ataxia Journal of Clinical Medicine doi: 10.3390/jcm9061630 Authors: Lise Legrand Carole Maupain Marie-Lorraine Monin Claire Ewenczyk Richard Isnard Rana Alkouri Alexandra Durr Francoise Pousset Background: Friedreich’s ataxia (FA) is a rare autosomal recessive mitochondrial disease resulting of a triplet repeat expansion guanine-adenine-adenine (GAA) in the frataxin...
Thu May 28, 2020 03:00
JCM, Vol. 9, Pages 1628: Regulation of Angiogenesis Discriminates Tissue Resident MSCs from Effective and Defective Osteogenic Environments Journal of Clinical Medicine doi: 10.3390/jcm9061628 Authors: R. J. Cuthbert E. Jones C. Sanjurjo-Rodríguez A. Lotfy P. Ganguly S. M. Churchman P. Castana H. B. Tan D. McGonagle E. Papadimitriou P. V. Giannoudis Background: The biological mechanisms that contribute to atrophic long bone non-union are poorly understood....
Thu May 28, 2020 03:00
JCM, Vol. 9, Pages 1631: Prevalence of Coronary Artery Calcification on Pre-Atrial Fibrillation Ablation CT Pulmonary Venograms and its Impact on Selection for Statin Therapy Journal of Clinical Medicine doi: 10.3390/jcm9061631 Authors: Michael P. Dunleavy Avirup Guha Andrea Cardona Christopher Fortuna Emile G. Daoud Subha V. Raman Thura T. Harfi Atherosclerotic cardiovascular disease (ASCVD) shares many risk factors with atrial fibrillation (AF). Obtaining computed...
Thu May 28, 2020 03:00
JCM, Vol. 9, Pages 1626: Is Gout Associated with Pyoderma Gangrenosum? A Population-Based Case-Control Study Journal of Clinical Medicine doi: 10.3390/jcm9061626 Authors: Khalaf Kridin Ralf J. Ludwig Dana Tzur Bitan Mouhammad Kridin Giovanni Damiani Arnon D. Cohen The coexistence of pyoderma gangrenosum (PG) and gout has been reported in individual patients; however, the association between these conditions has not been investigated. We aimed to assess the association...
Thu May 28, 2020 03:00
J. Imaging, Vol. 6, Pages 38: Spatially and Spectrally Concatenated Neural Networks for Efficient Lossless Compression of Hyperspectral Imagery Journal of Imaging doi: 10.3390/jimaging6060038 Authors: Zhuocheng Jiang W. David Pan Hongda Shen To achieve efficient lossless compression of hyperspectral images, we design a concatenated neural network, which is capable of extracting both spatial and spectral correlations for accurate pixel value prediction. Unlike conventional neural...
Thu May 28, 2020 03:00
J. Imaging, Vol. 6, Pages 37: Explainable Machine Learning Framework for Image Classification Problems: Case Study on Glioma Cancer Prediction Journal of Imaging doi: 10.3390/jimaging6060037 Authors: Emmanuel Pintelas Meletis Liaskos Ioannis E. Livieris Sotiris Kotsiantis Panagiotis Pintelas Image classification is a very popular machine learning domain in which deep convolutional neural networks have mainly emerged on such applications. These networks manage to achieve remarkable...
Thu May 28, 2020 03:00
Life, Vol. 10, Pages 79: Distinctive Features of PipX, a Unique Signaling Protein of Cyanobacteria Life doi: 10.3390/life10060079 Authors: Labella Cantos Salinas Espinosa Contreras PipX is a unique cyanobacterial protein identified by its ability to bind to PII and NtcA, two key regulators involved in the integration of signals of the nitrogen/carbon and energy status, with a tremendous impact on nitrogen assimilation and gene expression in cyanobacteria. PipX provides...
Thu May 28, 2020 03:00
Life, Vol. 10, Pages 80: Almond Skin Extracts and Chlorogenic Acid Delay Chronological Aging and Enhanced Oxidative Stress Response in Yeast Life doi: 10.3390/life10060080 Authors: Tungmunnithum Abid Elamrani Drouet Addi Hano Almond (Prunus dulcis (Mill.) D.A.Webb) is one of the largest nut crops in the world. Recently, phenolic compounds, mostly stored in almond skin, have been associated with much of the health-promoting behavior associated with their intake. The...
Thu May 28, 2020 03:00
Medicina, Vol. 56, Pages 265: Male Anabolic Androgenic Steroid Users with Personality Disorders Report More Aggressive Feelings, Suicidal Thoughts, and Criminality Medicina doi: 10.3390/medicina56060265 Authors: Annica Börjesson Christian Möller Anders Hagelin Veronica Vicente Anders Rane Mikael Lehtihet Marja-Liisa Dahl Nina Gårevik Lena Ekström Background and objectives: Anabolic androgenic steroids (AAS) are mainly used for aesthetic and performance-enhancing...
Thu May 28, 2020 03:00
Medicina, Vol. 56, Pages 264: Lower Cardiovascular Stress during Resistance Training Performed with Inter-Repetition Rests in Elderly Coronary Patients Medicina doi: 10.3390/medicina56060264 Authors: Ribeiro-Torres de Sousa Iglesias-Soler Fontes-Villalba Zouhal Carré Foster Boullosa Background and Objectives: Hemodynamic stress during resistance training is often a reason why this training method is not used in cardiac patients. A lifting protocol that imposes...
Thu May 28, 2020 03:00
Medicina, Vol. 56, Pages 266: Evaluating Effectiveness and Safety in Chronic Kidney Disease with Atrial Flutter Using an Anticoagulation Strategy Medicina doi: 10.3390/medicina56060266 Authors: Ying-Ting Wang Chung-Yu Chen Ming-Jong Bair Background and Objectives: Recent randomized trials of oral antithrombotic drugs with atrial flutter (AFL) excluded patients with renal impairment because of their increased risk of bleeding. To date, no relevant studies have assessed the effectiveness...
Thu May 28, 2020 03:00
Metabolites, Vol. 10, Pages 221: Metabolomics Study on Pathogenic and Non-pathogenic E. coli with Closely Related Genomes with a Focus on Yersiniabactin and Its Known and Novel Derivatives Metabolites doi: 10.3390/metabo10060221 Authors: Schulz Gaitanoglou Mantel Hövelmann Hübner Dobrindt Humpf The Escherichia coli (E. coli) strains Nissle 1917 (EcN), 83972 and CFT073 are closely related but differ in their phenotypes and pathogenicity. The aim of this study...
Thu May 28, 2020 03:00
Metabolites, Vol. 10, Pages 220: Non-Targeted Metabolite Profiles and Sensory Properties Elucidate Commonalities and Differences of Wines Made with the Same Variety but Different Cultivar Clones Metabolites doi: 10.3390/metabo10060220 Authors: Cuadros-Inostroza Verdugo-Alegría Willmitzer Moreno-Simunovic Vallarino Grapes, one of the oldest agricultural crops, are cultivated to produce table fruits, dried fruits, juice, and wine. Grapevine variety is composed of clones...
Thu May 28, 2020 03:00
Microorganisms, Vol. 8, Pages 813: Influence of High Hydrostatic Pressure on the Identification of Lactobacillus by MALDI-TOF MS- Preliminary Study Microorganisms doi: 10.3390/microorganisms8060813 Authors: Bucka-Kolendo Sokołowska Winiarczyk In the present study, we assessed the ability of MALDI-TOF MS (matrix-assisted laser desorption ionization time-of-flight mass spectrometry) to identify microbial strains subjected to high hydrostatic pressure (HHP) as a stress factor....
Thu May 28, 2020 03:00
Microorganisms, Vol. 8, Pages 812: Characterization of Indigenous Lactic Acid Bacteria in Cow Milk of the Maltese Islands: A Geographical and Seasonal Assessment Microorganisms doi: 10.3390/microorganisms8060812 Authors: Garroni Doulgeraki Pavli Spiteri Valdramidis A geographical and seasonal assessment of indigenous lactic acid bacteria (LAB) in Maltese cow milk was conducted in this study. To investigate this, milk was collected from different regions of Malta during...
Thu May 28, 2020 03:00
Microorganisms, Vol. 8, Pages 811: Age and Species of Eucalyptus Plantations Affect Soil Microbial Biomass and Enzymatic Activities Microorganisms doi: 10.3390/microorganisms8060811 Authors: Xu Liu Qu Ma Sun Soil microorganisms and extracellular enzymes play important roles in soil nutrient cycling. Currently, China has the second-largest area of eucalyptus plantations in the world. Information on the effects of eucalyptus age and species of trees on soil microbial biomass...
Thu May 28, 2020 03:00
Microorganisms, Vol. 8, Pages 810: Long-Term Antibiotic Prophylaxis in Urology and High Incidence of Clostridioides difficile Infections in Surgical Adult Patients Microorganisms doi: 10.3390/microorganisms8060810 Authors: Jachowicz Wałaszek Sulimka Maciejczak Zieńczuk Kołodziej Karaś Pobiega Wojkowska-Mach Clostridioides difficile infections are the main cause of antibiotic-related diarrhea. Most of them come in the form of healthcare-associated Clostridioides...
Thu May 28, 2020 03:00
Molecules, Vol. 25, Pages 2527: Combined Effect of Nitrofurantoin and Plant Surfactant on Bacteria Phospholipid Membrane Molecules doi: 10.3390/molecules25112527 Authors: Rojewska Smułek Prochaska Kaczorek Due to the increasing use of antibiotics, measures are being taken to improve their removal from the natural environment. The support of biodegradation with natural surfactants that increase the bioavailability of impurities for microorganisms that degrade them, raises...
Thu May 28, 2020 03:00
Molecules, Vol. 25, Pages 2526: The Interaction of Hydrogen with the van der Waals Crystal γ-InSe Molecules doi: 10.3390/molecules25112526 Authors: James Felton Elena Blundo Sanliang Ling Joseph Glover Zakhar R. Kudrynskyi Oleg Makarovsky Zakhar D. Kovalyuk Elena Besley Gavin Walker Antonio Polimeni Amalia Patané The emergence of the hydrogen economy requires development in the storage, generation and sensing of hydrogen. The indium selenide ( γ...
Thu May 28, 2020 03:00
Molecules, Vol. 25, Pages 2525: Five New Pregnane Glycosides from Gymnema sylvestre and Their α-Glucosidase and α-Amylase Inhibitory Activities Molecules doi: 10.3390/molecules25112525 Authors: Kiem Yen Hung Nhiem Tai Trang Yen Ngoc Minh Park Lee Kim Kim Gymnema sylvestre, a medicinal plant, has been used in Indian ayurvedic traditional medicine for the treatment of diabetes. Phytochemical investigation of Gymnema sylvestre led to the...
Thu May 28, 2020 03:00
Molecules, Vol. 25, Pages 2522: Detecting Low Concentrations of Nitrogen-Based Adulterants in Whey Protein Powder Using Benchtop and Handheld NIR Spectrometers and the Feasibility of Scanning through Plastic Bag Molecules doi: 10.3390/molecules25112522 Authors: Zaukuu Aouadi Lukács Bodor Vitális Gillay Gillay Friedrich Kovacs Nitrogen-rich adulterants in protein powders present sensitivity challenges to conventional combustion methods of protein determination...
Thu May 28, 2020 03:00
Molecules, Vol. 25, Pages 2523: Discovery of New Apoptosis-Inducing Agents for Breast Cancer Based on Ethyl 2-Amino-4,5,6,7-Tetra Hydrobenzo[b]Thiophene-3-Carboxylate: Synthesis, In Vitro, and In Vivo Activity Evaluation Molecules doi: 10.3390/molecules25112523 Authors: Gad Nafie Eltamany Hammad Barakat Boraei A multicomponent synthesis was empolyed for the synthesis of ethyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate 1. An interesting cyclization...
Thu May 28, 2020 03:00
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