Chromosomal rearrangements, such as duplications/deletions, can lead to a variety of genetic disorders. Herein, we reported a prenatal case with right aortic arch and aberrant left subclavian artery, consisting of a complex chromosomal copy number variations. Routine cytogenetic analysis described the chromosomal karyotype as 46,XY, add (2)(q37) for the fetus. However, the chromosomal microarray analysis (CMA) identified a 22.4 Mb duplication in chromosome 4p16.3p15.2, a 3.96 Mb microduplication...
Thu May 28, 2020 11:05
Background. Patent foramen ovale (PFO) has been linked to the pathophysiology of cryptogenic stroke. Contrast transesophageal echocardiography (cTEE) is the current gold standard for PFO diagnosis, but it has the disadvantage of being semi-invasive and does not exempt from risks. As a diagnostic test, the efficacy of contrast transthoracic echocardiography (cTTE) and contrast transcranial Doppler (cTCD) is controversial. This study is aimed at investigating the efficacy of cTTE and cTCD versus cTEE...
Thu May 28, 2020 10:35
Licochalcone A (LCA) exhibited anticancer activity through modulating reactive oxygen species (ROS) levels in some cancer cells and has been evidenced to suppress colorectal cancer (CRC) formation and progression. However, whether LCA mediates the progression of CRC by regulating ROS production remains unclear. To address this, HCT-116 cells were treated with LCA, resulting in G0/G1 phase arrest, apoptosis, and high ROS generation, which were attenuated by N-acetyl-L-cysteine, a ROS inhibitor. In...
Thu May 28, 2020 08:35
Publication date: June 2020Source: Archives of Physical Medicine and Rehabilitation, Volume 101, Issue 6Author(s):
Thu May 28, 2020 22:56
Publication date: June 2020Source: Archives of Physical Medicine and Rehabilitation, Volume 101, Issue 6Author(s):
Thu May 28, 2020 22:56
Publication date: June 2020Source: Archives of Physical Medicine and Rehabilitation, Volume 101, Issue 6Author(s): Yun-Juan Xie, Qiang Gao, Cheng-Qi He, Rong Bian
Thu May 28, 2020 22:56
Publication date: June 2020Source: Archives of Physical Medicine and Rehabilitation, Volume 101, Issue 6Author(s):
Thu May 28, 2020 22:56
Publication date: June 2020Source: Archives of Physical Medicine and Rehabilitation, Volume 101, Issue 6Author(s):
Thu May 28, 2020 22:56
Publication date: June 2020Source: Archives of Physical Medicine and Rehabilitation, Volume 101, Issue 6Author(s):
Thu May 28, 2020 22:56
Abstract Purpose Pancreatic neuroendocrine neoplasms (PNENs) are a group of clinically rare and heterogeneous tumors of the pancreas. Currently there are no studies investigating the gender difference in PNEN susceptibility. Thus, the purpose of this study was aimed at examining how gender shapes risk factors, clinicopathological features, and comorbidities in PNENs. Methods...
Thu May 28, 2020 03:00
Publication date: Available online 28 May 2020Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Johanna Mirsch, Lisa Hintz, Andreas Maier, Claudia Fournier, Markus Löbrich
Thu May 28, 2020 22:30
Publication date: Available online 28 May 2020Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): J. Martin Brown
Thu May 28, 2020 22:30
Abstract An accurate assessment of surgical operation skills is essential for improving the vascular intervention surgical outcome and the performance of endovascular surgery robots. In existing studies, subjective and objective assessments of surgical operation skills use a variety of indicators, such as the operation speed and operation smoothness. However, the vascular conditions of particular patients have not been considered in the assessment, leading to deviations in the...
Thu May 28, 2020 03:00
Neural transplantation is a promising modality for treatment of neurodegenerative diseases, traumatic brain injury and stroke. Biocompatible scaffolds with optimized properties improve the survival of transplanted neural cells and differentiation of progenitor cells into the desired types of neurons. Silk fibroin is a biocompatible material for tissue engineering. Here, we describe thin-film scaffolds based on photocrosslinked methacrylated silk fibroin (FBMA). These scaffolds exhibit an increased...
Wed May 27, 2020 03:00
Journal of Cutaneous Medicine and Surgery, Ahead of Print. BackgroundA growing interest exists in the relationship between diet and skin disease, with many recent studies identifying a role for omega-3 fatty acids (O3FAs) in various dermatological conditions.ObjectiveOur objective was to identify the spectrum of uses for O3FA supplementation reported in literature and to evaluate the current level of evidence for its clinical application in skin disease prevention and management.MethodsA search was...
Thu May 28, 2020 05:07
Journal of Cutaneous Medicine and Surgery, Ahead of Print.
Thu May 28, 2020 04:18
Publication date: July 2020Source: European Journal of Cancer, Volume 134Author(s): Fabian Wolpert, Anna S. Berghoff, Bettina Grossenbacher, Anna Lareida, Raphael Löb, Patrick Roth, Marian C. Neidert, Nicolaus Andratschke, Emilie Le Rhun, Matthias Preusser, Michael Weller
Thu May 28, 2020 20:53
A suite of grounding-line landforms on the Antarctic seafloor, imaged at submeter horizontal resolution from an autonomous underwater vehicle, enables calculation of ice sheet retreat rates from a complex of grounding-zone wedges on the Larsen continental shelf, western Weddell Sea. The landforms are delicate sets of up to 90 ridges, <1.5 meters high and spaced 20 to 25 meters apart. We interpret these ridges as the product of squeezing up of soft sediment during the rise and fall of the retreating...
Thu May 28, 2020 20:40
Bacteria were first detected in human tumors more than 100 years ago, but the characterization of the tumor microbiome has remained challenging because of its low biomass. We undertook a comprehensive analysis of the tumor microbiome, studying 1526 tumors and their adjacent normal tissues across seven cancer types, including breast, lung, ovary, pancreas, melanoma, bone, and brain tumors. We found that each tumor type has a distinct microbiome composition and that breast cancer has a particularly...
Thu May 28, 2020 20:40
The efficient removal of alkyne impurities for the production of polymer-grade lower olefins remains an important and challenging goal for many industries. We report a strategy to control the pore interior of faujasite (FAU) zeolites by the confinement of isolated open nickel(II) sites in their six-membered rings. Under ambient conditions, Ni@FAU showed remarkable adsorption of alkynes and efficient separations of acetylene/ethylene, propyne/propylene, and butyne/1,3-butadiene mixtures, with unprecedented...
Thu May 28, 2020 20:40
Thu May 28, 2020 20:40
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