The expansive window of the ICU room looks out over a gorgeous Sunday sunset. The room is pristine and organized. Monitors beep reassuringly. An incentive spirometer and a paper menu rest — comically, given the situation — on the bedside table. Everything in the room is familiar to me; I’m a…
Thu May 28, 2020 03:00
Metastatic castration-resistant prostate cancer is a heterogeneous disease with poor outcomes. Tumors in up to 30% of patients harbor deleterious aberrations in genes involved in repairing DNA damage. Among the most common of these alterations, BRCA1 and BRCA2 are well-characterized genes involved…
Thu May 28, 2020 03:00
Timely administration of naloxone can save lives in the event of opioid overdose. Thus, emergency treatment provided by persons who may be at the scene of an overdose plays a crucial role in addressing the ongoing global opioid crisis. World Health Organization guidelines recommend that all persons…
Thu May 28, 2020 03:00
Hospital closures disrupt communities. They also demand that we clarify our goals: Do we come together to support endangered hospitals, or do we support the patients and communities relying on them? Sometimes the second requires the first, but not always. For 245 years, the Philadelphia General…
Wed May 27, 2020 03:00
Nursing homes have been caught in the crosshairs of the coronavirus pandemic. As of early May 2020, Covid-19 had claimed the lives of more than 28,000 nursing home residents and staff in the United States. But U.S. nursing homes were unstable even before Covid-19 hit. They were like tinderboxes,…
Wed May 27, 2020 03:00
Surveillance of the clinical characteristics and outcomes of hospitalized patients with coronavirus disease 2019 (Covid-19) is imperative for elucidating the epidemiology of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the United States. As of May 13, 2020, the United States…
Wed May 27, 2020 03:00
Beigel et al. have provided in the Journal the first report of an effective treatment for Covid-19, resulting from a rigorously designed and conducted clinical trial. It is remarkable that a randomized, placebo-controlled trial of a potential antiviral treatment for a disease whose pathogenesis is…
Wed May 27, 2020 03:00
We are both physician trainees — a cardiology fellow and a general surgery resident — in New York City. We are one of the nearly 10,000 dual-physician couples nationwide who, over the past 30 years, have embarked on the arduous journey of medical training together. Like many of our colleagues…
Wed May 27, 2020 03:00
Presentation of Case. Dr. Kathy M. Tran: A 74-year-old man with mantle-cell lymphoma was admitted to this hospital during the coronavirus disease 2019 (Covid-19) pandemic because of acute respiratory failure. One day before this admission, productive cough and dyspnea developed. The next day, when…
Wed May 27, 2020 03:00
Abstract Purpose of Review The growing prevalence of spinal pain in the USA continues to produce substantial economic impact and strain on health-related quality of life. Percutaneous adhesiolysis is utilized for recalcitrant, resistant conditions involving spinal pain when epidural injections have failed to provide adequate improvement, especially low back and lower extremity pain, specifically in post-lumbar surgery syndrome....
Thu May 28, 2020 03:00
Liwen He, Feiran Zhang, Zhengyang Jian, Jiachen Sun, Jiamin Chen, Vuekhang Liapao, Qing HeSaudi Journal of Gastroenterology 2020 26(3):153-159Background/Aim: Ulcerative colitis (UC) has been implicated to imbalanced enteric flora and reduced microbial diversity. Stachyose is a kind of natural prebiotic which favorably modulate the composition of the gut microbiota. The present study aims to investigate the effects of stachyose on inflammatory levels and gut microbiota of acute colitis mice. Materials...
Wed May 27, 2020 00:00
Li Jiao, Junmin Wang, Wenjuan Zhao, Xinying Zhu, Xia Meng, Liwei ZhaoSaudi Journal of Gastroenterology 2020 26(3):137-143Background/Aim: Low residue diet (LRD) has a similar quality of bowel preparation with clear liquid diet before colonoscopy, but improved patient tolerance. However, the optimal LRD duration is still controversial. In this study, we have compared the effect of a 1-day LRD and 2-day LRD on the quality of bowel preparation and patient tolerance. Patients and Methods: Our prospective,...
Wed May 27, 2020 00:00
Muhammad I. O. Rahman, Brian P. H. Chan, Parsa M Far, Lawrence Mbuagbaw, Lehana Thabane, Mohammad YaghoobiSaudi Journal of Gastroenterology 2020 26(3):113-119 Background/Aim: Endoscopic ultrasound (EUS) and contrast-enhanced computed tomography (CT) with pancreas protocol are used in assessing the resectability of neoplastic pancreatic lesions. Here, we performed a diagnostic test accuracy (DTA) meta-analysis, comparing the diagnostic accuracy of EUS and CT in evaluating the resectability of pancreatic...
Wed May 27, 2020 00:00
Lorenzo Ridola, Oliviero Riggio, Stefania Gioia, Silvia NardelliSaudi Journal of Gastroenterology 2020 26(3):111-112
Wed May 27, 2020 00:00
Ming Luo, Xiao-Bing Yu, Sheng-Juan Hu, Fei-Hu BaiSaudi Journal of Gastroenterology 2020 26(3):120-128Background/Aim: A novel computerised Stroop test- EncephalApp Stroop App (EncephalApp) has good diagnostic validity for minimal hepatic encephalopathy (MHE) in cirrhotic patients. The Stroop test is correlated with sleep disturbances which are common, and severely affects health-related quality of life in cirrhotic patients with MHE. We evaluated the relationship between sleep quality and EncephalApp...
Wed May 27, 2020 00:00
Yalei Zhao, Xiaoyun Zhang, Yabin Liu, Yiping Ma, Pong Kong, Tianliang Bai, Mei Han, Binghui LiSaudi Journal of Gastroenterology 2020 26(3):144-152Background/Aims: Colorectal cancer (CRC) is the third most common malignant tumour worldwide and the second leading cause of cancer-related deaths. Commonly, 5'-aminolevulinic acid synthase1 (ALAS1) is the rate-limiting enzyme for haem biosynthesis. Recent studies have shown that ALAS1 is involved in a number of cellular functions and has significant effects...
Wed May 27, 2020 00:00
Jing Wang, Haibin Zhou, Yucheng Wang, Haitao Huang, Jing Yang, Weigang Gu, Xiaofeng Zhang, Jianfeng YangSaudi Journal of Gastroenterology 2020 26(3):129-136Background/Aims: The aim of this study is to evaluate serum mucin 3A (MUC3A) as a candidate biomarker for extrahepatic cholangiocarcinoma (EHCC). Patients and Methods: 35 Patients with EHCC, 30 patients with pancreatic cancer, 35 patients with gallbladder carcinoma and 78 patients with benign biliary disease were enrolled during January 2015...
Wed May 27, 2020 00:00
Qiang Zhang, Kangjing Xu, Ming Chen, Yongchang Miao, Nuofan Wang, Zekuan Xu, Hao XuSaudi Journal of Gastroenterology 2020 26(3):160-167 Background/Aim: Liquid biopsy is changing the diagnosis and treatment strategies of various neoplasms. However, the circulating tumor cells (CTCs) of gastrointestinal stromal tumor (GIST) patients with different disease process are not clear. To better understand the dynamic change of CTCs in GIST patients, we conducted a real-life setting study. Patients and...
Wed May 27, 2020 00:00
Journal of Adolescent and Young Adult Oncology, Ahead of Print.
Wed May 27, 2020 10:00
Journal of Adolescent and Young Adult Oncology, Ahead of Print.
Wed May 27, 2020 10:00
Related ArticlesIndependent Validation of Tumor Budding Activity and Cell Nest Size as Determinants of Patient Outcome in Squamous Cell Carcinoma of the Uterine Cervix. Am J Surg Pathol. 2020 May 22;: Authors: Zare SY, Aisagbonhi O, Hasteh F, Fadare O Abstract A novel 3-tiered grading system that combines tumor budding activity and cell nest size has been found to be highly prognostic in squamous cell carcinomas (SCCs) of various sites, including lung,...
Thu May 28, 2020 07:36
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