Related ArticlesObesity is correlated with poor outcome after allogeneic hematopoietic stem cell transplantation in patients with acute leukemia. Jpn J Clin Oncol. 2020 May 27;: Authors: Yu J, Lin S, Luo Y, Shi J, Tan Y, Lai X, Zhao Y, Ye Y, Zhu Y, Zheng W, Huang H Abstract OBJECTIVE: The relationship between body mass index and overall survival has been controversial in patients who suffered from hematological malignancies and underwent hematopoietic...
Thu May 28, 2020 14:15
Long intergenic non-protein coding RNA 520 (LINC00520), a novel identified lncRNA, has been shown to modulate the malignant phenotype of tumor cells in some malignant tumors. However, the exact role and molecu...
Thu May 28, 2020 03:00
In a large number of cancer types, treatment selection depends on the presence of specific tumor biomarkers. Due to the dynamic nature of cancer, very often these predictive biomarkers are not uniformly presen...
Wed May 27, 2020 03:00
Publication date: Available online 27 May 2020Source: The Journal of Prosthetic DentistryAuthor(s): Mei-Yang Huang, KeunBaDa Son, Kyu-Bok Lee
Thu May 28, 2020 13:13
Related ArticlesMembranoproliferative Glomerulonephritis and Mixed Cryoglobulinemia as a Form of Presentation of Visceral Leishmaniasis. Am J Case Rep. 2020 May 27;21:e921445 Authors: Padrón Romero M, Acevedo Ribó MM, Ahijado Hormigos FJ, Díaz Crespo F, Cueto Bravo L, Herraiz Corredor C, Fernández Rojo MÁ, Díaz-Tejeiro Izquierdo R Abstract BACKGROUND Visceral leishmaniasis (VL) is an endemic systemic disease in the Mediterranean countries, including...
Thu May 28, 2020 17:11
Related ArticlesDiscovery of a Glass Splinter in the Abdominal Cavity After an Old Impalement Injury: A Case Report and Literature Review. Am J Case Rep. 2020 May 27;21:e922599 Authors: Luks B, Dworzyńska A, Dobrogowski M, Pomorski L Abstract BACKGROUND Intra-abdominal impalement injuries caused by a penetrating foreign body are rare and often fatal. The mechanism of injury is usually associated with vascular and organ damage, and the course is dynamic,...
Thu May 28, 2020 13:11
Related ArticlesEstimating daytime sleepiness with previous night EEG, EOG and EMG spectrograms in patients with suspected sleep apnea using a convolutional neural network. Sleep. 2020 May 27;: Authors: Nikkonen S, Korkalainen H, Kainulainen S, Myllymaa S, Leino A, Kalevo L, Oksenberg A, Leppänen T, Töyräs J Abstract A common symptom of obstructive sleep apnea (OSA) is excessive daytime sleepiness (EDS). The gold standard test for EDS is the multiple...
Thu May 28, 2020 15:34
Related ArticlesDisturbed nighttime sleep in children and adults with rhythmic movement disorder. Sleep. 2020 May 27;: Authors: Laganière C, Pennestri MH, Rassu AL, Barateau L, Chenini S, Evangelista E, Dauvilliers Y, Lopez R Abstract STUDY OBJECTIVES: Rhythmic movements during sleep are frequent and often considered as benign in children. Disabling forms are diagnosed as rhythmic movement disorder and may persist in adulthood. Whether rhythmic movements...
Thu May 28, 2020 15:34
Related Articles[Dental sleep medicine: A further introduction to an emerging dental discipline]. Ned Tijdschr Tandheelkd. 2020 Apr;127(4):222-230 Authors: Lobbezoo F, Aarab G Abstract Dental sleep medicine is a discipline traditionally focusing on sleep-breathing disorders like snoring and obstructive sleep apnea. In everyday clinical practice, however, such disorders rarely occur in isolation. Rather, they frequently co-occur with other sleep disorders...
Thu May 28, 2020 15:34
Related ArticlesAssociation between severity of obstructive sleep apnea and high-sensitivity C-reactive protein in patients with hypertrophic obstructive cardiomyopathy. Clin Cardiol. 2020 May 27;: Authors: Wang J, Xu H, Guo C, Duan X, Hu F, Yang W, Cui J, Song L, Chun Y, Yuan J, Qiao S Abstract BACKGROUND: Obstructive sleep apnea (OSA) is highly prevalent in patients with hypertrophic obstructive cardiomyopathy (HOCM). Inflammatory responses are increased...
Thu May 28, 2020 13:10
Related ArticlesImpact of low arousal threshold on treatment of obstructive sleep apnea in patients with post-traumatic stress disorder. Sleep Breath. 2020 May 27;: Authors: A El-Solh A, Lawson Y, Wilding GE Abstract PURPOSE: We sought to determine the prevalence of low arousal threshold (LAT) in veterans with post-traumatic stress disorder (PTSD) and whether or not LAT is associated with decreased use of continuous positive airway pressure (CPAP). ...
Thu May 28, 2020 13:10
Related ArticlesAdiponectin ameliorates lung injury induced by intermittent hypoxia through inhibition of ROS-associated pulmonary cell apoptosis. Sleep Breath. 2020 May 26;: Authors: Ding W, Zhang X, Zhang Q, Dong Y, Wang W, Ding N Abstract PURPOSE: Obstructive sleep apnea hypopnea syndrome has been reported to be associated with pulmonary hypertension (PH). Adiponectin (Ad) has many protective roles in the human body, including its function as an anti-inflammatory...
Thu May 28, 2020 13:10
Related ArticlesIs cellular energy monitoring more responsive to hypoxia than pulse oximetry? Sleep Breath. 2020 May 26;: Authors: Hatch GM, Ashbrook L, Prather AA, Krystal AD Abstract PURPOSE: Pulse oximetry is the current standard for detecting drops in arterial blood oxygen saturation (SpO2) associated with obstructive sleep apnea and hypopnea events in polysomnographic (PSG) testing. However, cellular energy monitoring (CE monitoring), a measure...
Thu May 28, 2020 13:10
Related ArticlesObservational Study of Pulse Transit Time in Children With Sleep Disordered Breathing. Front Neurol. 2020;11:316 Authors: Yanney MP, Prayle AP, Rowbotham NJ, Kurc M, Tilbrook S, Ali N Abstract Background: Pulse transit time (PTT) is a non-invasive measure of arousals and respiratory effort for which we aim to identify threshold values that detect sleep disordered breathing (SDB) in children. We also compare the sensitivity and specificity...
Thu May 28, 2020 13:10
Related ArticlesAssociation Between Proton Pump Inhibitors and Asthma: A Population-Based Cohort Study. Front Pharmacol. 2020;11:607 Authors: Wang YT, Tsai MC, Wang YH, Wei JC Abstract Objective: The relationship between proton pump inhibitors (PPIs) and asthma is controversial. The goal of this study was to determine the association between PPI use in non-asthma subjects and their subsequent asthma prevalence. Design: Nationwide, population-based...
Thu May 28, 2020 13:10
Related ArticlesHealth Supervision for People With Achondroplasia. Pediatrics. 2020 May 26;: Authors: Hoover-Fong J, Scott CI, Jones MC, COMMITTEE ON GENETICS Abstract Achondroplasia is the most common short-stature skeletal dysplasia, additionally marked by rhizomelia, macrocephaly, midface hypoplasia, and normal cognition. Potential medical complications associated with achondroplasia include lower extremity long bone bowing, middle-ear dysfunction,...
Thu May 28, 2020 13:10
Related ArticlesRespiratory Monitoring in General Care Units. Respir Care. 2020 Jun;65(6):870-881 Authors: Lamberti JP Abstract Respiratory compromise is a common and potentially dangerous complication of patients admitted to general care units of hospitals. There are several distinct and disparate pathophysiologic trajectories of respiratory deterioration that hospitalized patients may suffer. Obstructive sleep apnea and preexisting cardiopulmonary...
Thu May 28, 2020 13:10
Related ArticlesEffect of ambient temperature on sleep breathing phenotype in mice: the role of orexins. J Exp Biol. 2020 May 26;: Authors: Berteotti C, Lo Martire V, Alvente S, Bastianini S, Matteoli G, Silvani A, Zoccoli G Abstract The loss of orexinergic neurons, releasing orexins, results in narcolepsy. Orexins participate in the regulation of many physiological functions, and their role as wake-promoting molecules has been widely described. Less...
Thu May 28, 2020 13:10
Related ArticlesA signal demodulation-based method for the early detection of Cheyne-Stokes respiration. PLoS One. 2020;15(3):e0221191 Authors: Guyot P, Djermoune EH, Chenuel B, Bastogne T Abstract Cheyne-Stokes respiration (CSR) is a sleep-disordered breathing characterized by recurrent central apneas alternating with hyperventilation exhibiting a crescendo-decrescendo pattern of tidal volume. This respiration is reported in patients with heart failure,...
Thu May 28, 2020 13:10
Related ArticlesThe Epidemiology of Patient-Reported Hypersomnia in Persons With Advanced Age. J Am Geriatr Soc. 2019 12;67(12):2545-2552 Authors: Miner B, Gill TM, Yaggi HK, Redeker NS, Van Ness PH, Han L, Vaz Fragoso CA Abstract OBJECTIVE: To examine the epidemiology and key demographic and clinical correlates of patient-reported hypersomnia in persons with advanced age. DESIGN: Cross-sectional design. SETTING: Community. ...
Thu May 28, 2020 13:10
Related ArticlesUse of web-based game in neonatal resuscitation - is it effective? BMC Med Educ. 2020 May 26;20(1):170 Authors: Yeo CL, Ho SKY, Tagamolila VC, Arunachalam S, Bharadwaj SS, Poon WB, Tan MG, Edison PE, Yip WY, Haium AAA, Jayagobi PA, Vora SJ, Khurana SK, Allen JC, Lustestica EI Abstract BACKGROUND: Knowledge and skills decline within months post simulation-based training in neonatal resuscitation. To empower 'Millennial' learners to take...
Thu May 28, 2020 13:07
Related ArticlesImproving the assessment of communication competencies in a national licensing OSCE: lessons learned from an experts' symposium. BMC Med Educ. 2020 May 26;20(1):171 Authors: Monti M, Klöckner-Cronauer C, Hautz SC, Schnabel KP, Breckwoldt J, Junod-Perron N, Feller S, Bonvin R, Huwendiek S Abstract BACKGROUND: As the communication competencies of physicians are crucial for providing optimal patient care, their assessment in the context...
Thu May 28, 2020 13:07
Related ArticlesStimulus-specific adaptation to behaviorally-relevant sounds in awake rats. PLoS One. 2020;15(3):e0221541 Authors: Yaron A, Jankowski MM, Badrieh R, Nelken I Abstract Stimulus-specific adaptation (SSA) is the reduction in responses to a common stimulus that does not generalize, or only partially generalizes, to other stimuli. SSA has been studied mainly with sounds that bear no behavioral meaning. We hypothesized that the acquisition...
Thu May 28, 2020 13:05
Related ArticlesThe role of adaptation in generating monotonic rate codes in auditory cortex. PLoS Comput Biol. 2020 02;16(2):e1007627 Authors: Lee JH, Wang X, Bendor D Abstract In primary auditory cortex, slowly repeated acoustic events are represented temporally by the stimulus-locked activity of single neurons. Single-unit studies in awake marmosets (Callithrix jacchus) have shown that a sub-population of these neurons also monotonically increase...
Thu May 28, 2020 13:05
Related ArticlesElectrophysiological characteristics in children with listening difficulties, with or without auditory processing disorder. Int J Audiol. 2019 11;58(11):704-716 Authors: Mattsson TS, Lind O, Follestad T, Grøndahl K, Wilson W, Nicholas J, Nordgård S, Andersson S Abstract Objective: To determine if the auditory middle latency responses (AMLR), auditory late latency response (ALLR) and auditory P300 were sensitive to auditory processing...
Thu May 28, 2020 13:05
Related ArticlesNeuronal phase consistency tracks dynamic changes in acoustic spectral regularity. Eur J Neurosci. 2019 05;49(10):1268-1287 Authors: Gifford AM, Sperling MR, Sharan A, Gorniak RJ, Williams RB, Davis K, Kahana MJ, Cohen YE Abstract The brain parses the auditory environment into distinct sounds by identifying those acoustic features in the environment that have common relationships (e.g., spectral regularities) with one another and then...
Thu May 28, 2020 13:05
Thu May 28, 2020 03:00
Metastatic castration-resistant prostate cancer is a heterogeneous disease with poor outcomes. Tumors in up to 30% of patients harbor deleterious aberrations in genes involved in repairing DNA damage. Among the most common of these alterations, BRCA1 and BRCA2 are well-characterized genes involved…
Thu May 28, 2020 03:00
Hereditary cancer syndromes, which account for approximately 10% of all cancers, serve as powerful models for the practice of precision medicine. The identification of genes that are associated with seemingly rare cancer-predisposition syndromes often provides insights regarding aspects of normal…
Thu May 28, 2020 03:00
Timely administration of naloxone can save lives in the event of opioid overdose. Thus, emergency treatment provided by persons who may be at the scene of an overdose plays a crucial role in addressing the ongoing global opioid crisis. World Health Organization guidelines recommend that all persons…
Thu May 28, 2020 03:00
The global pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has plunged large parts of the world into a protracted medical, social, and economic crisis. Coronavirus disease 2019 (Covid-19), the respiratory illness caused by SARS-CoV-2 infection, has caused over a quarter…
Wed May 27, 2020 03:00
Surveillance of the clinical characteristics and outcomes of hospitalized patients with coronavirus disease 2019 (Covid-19) is imperative for elucidating the epidemiology of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the United States. As of May 13, 2020, the United States…
Wed May 27, 2020 03:00
In patients with chronic kidney disease, the abnormal activation of inflammatory pathways is usually an important factor leading to renal fibrosis and further deterioration of renal function. Finding effective intervention targets of the inflammatory signaling pathway is an important way to treat chronic kidney disease. As a newly discovered lysosomal membrane protein, the correlation between SID1 transmembrane family member 2 (Sidt2) and the inflammatory signaling pathway has not been reported....
Thu May 28, 2020 08:05
Abstract Background Dental anxiety is a condition associated with avoidance of dental treatment and increased medical and surgical risks. This systematic review aims to summarize available evidence on conscious sedation techniques used for the management of Dental anxiety in patients scheduled for third molar extraction surgery, to identify best approaches and knowledge gaps. ...
Thu May 28, 2020 03:00
Abstract Coronary artery bypass grafts (CABG) surgery is an invasive procedure performed to circumvent partial or complete blood flow blockage in coronary artery disease (CAD). In this work, we apply a numerical optimal flow control model to patientspecific geometries of CABG, reconstructed from clinical images of real‐life surgical cases, in parameterized settings. The aim of these applications is to match known physiological data with numerical hemodynamics corresponding to different scenarios,...
Wed May 27, 2020 11:56
Allergic rhinitis (AR) is an inflammatory disease of the nasal mucosa impacting up to 25% of Canadians. The standard of care for AR includes a treatment plan that takes into account patient preferences, the se...
Wed May 27, 2020 03:00
Hereditary angioedema (HAE) is caused by a SERPING1 gene defect resulting in decreased (Type I) or dysfunctional (Type II) C1 esterase inhibitor (C1-INH). The prevalence of autoimmune diseases (ADs) in patient...
Wed May 27, 2020 03:00
In this letter to the editor, we present results of claims data analysis. This claims data analysis supports a hypothesis that in patients with hereditary angioedema due to C1-esterase inhibitor (C1-INH) defic...
Wed May 27, 2020 03:00
Mucus hypersecretion and goblet cell upregulation are common features of chronic rhinosinusitis with nasal polyps (CRSwNP). Although epidermal growth factor (EGF) has been reported to stimulate the expression ...
Wed May 27, 2020 03:00
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