Resolution of apnoeas in slow wave sleep.

Resolution of apnoeas in slow wave sleep.

Sleep Breath. 2015 Oct 21;

Authors: Koutsourelakis I, Lamprou K, Vagiakis E, Zakynthinos S

PMID: 26490752 [PubMed - as supplied by publisher]

from #ENT-PubMed via ola Kala on Inoreader http://ift.tt/1KtCNK6
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Head and Neck Medicine

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Head and Neck

Comparing staging by positron emission tomography with contrast-enhanced computed tomography and by pathology in head and neck squamous cell carcinoma.

 

J Laryngol Otol. 2015 Oct 22;:1-7Authors: Qualliotine JR, Mydlarz WK, Chan JY, Zhou X, Wang H, Agrawal NAbstract OBJECTIVE: This study aimed to evaluate the ability of positron emission tomography with contrast-enhanced computed tomography to correctly stage head and neck squamous cell carcinomas,...

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Head and Neck

Risk of decline and chance of improvement in olfaction among patients with post-traumatic olfactory loss.

 

J Laryngol Otol. 2015 Oct 22;:1-7Authors: Kuo CL, Shu CHAbstractOBJECTIVE: To evaluate the chance of improvement and risk of decline in olfaction among patients with post-traumatic olfactory loss.METHODS: This study comprised 80 patients. Changes in olfaction were determined using a visual analogue...

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Head and Neck

Head and Neck Diseases

 

36mHead and NeckInter-patient variability in docetaxel pharmacokinetics: A review. Authors: Nieuweboer AJ, de Morrée ES, de Graan AJ, Sparreboom A, de Wit R, Mathijssen RHAbstract Docetaxel is a frequently used chemotherapeutic agent in the treatment of solid cancers. Because of the large inter-individual...

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Head and Neck

Inter-patient variability in docetaxel pharmacokinetics: A review.

 

Authors: Nieuweboer AJ, de Morrée ES, de Graan AJ, Sparreboom A, de Wit R, Mathijssen RHAbstract Docetaxel is a frequently used chemotherapeutic agent in the treatment of solid cancers. Because of the large inter-individual variability (IIV) in the pharmacokinetics (PK) of docetaxel, it is challenging...

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Head and Neck

The emerging role of hypoxia-inducible factor-2 involved in chemo/radioresistance in solid tumors.

 

Authors: Zhao J, Du F, Luo Y, Shen G, Zheng F, Xu BAbstract The hypoxic condition is a common feature that negatively impacts the efficacy of radio- and chemotherapy in solid tumors. Hypoxia-inducible factors (HIF-1, 2, 3) predominantly regulate the adaptation to hypoxia at the cellular or organismal...

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Head and Neck

Cancer of Unknown Primary origin in the genomic era: Elucidating the dark box of cancer.

 

Authors: Economopoulou P, Mountzios G, Pavlidis N, Pentheroudakis GAbstract Cancer of Unknown Primary (CUP) comprises a heterogeneous disease group with diagnosis of metastatic malignancy in the absence of an identifiable primary site after diagnostic work up. CUP may either resemble a specific...

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Head and Neck

Local hyperthermia combined with radiotherapy and-/or chemotherapy: Recent advances and promises for the future.

 

Authors: Datta NR, Ordóñez SG, Gaipl US, Paulides MM, Crezee H, Gellermann J, Marder D, Puric E, Bodis SAbstract Hyperthermia, one of the oldest forms of cancer treatment involves selective heating of tumor tissues to temperatures ranging between 39 and 45°C. Recent developments based on the...

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Head and Neck

ErbB small molecule tyrosine kinase iDiarrhoea is a common, debilitating and potentially life threatening toxicity of many cancer therapiesnhibitor (TKI) induced diarrhoea: Chloride secretion as a mechanistic hypothesis.

 

ErbB small molecule tyrosine kinase inhibitor (TKI) induced diarrhoea: Chloride secretion as a mechanistic hypothesis.: Authors: Van Sebille YZ, Gibson RJ, Wardill HR, Bowen JMAbstract Diarrhoea is a common, debilitating and potentially life threatening toxicity of many cancer therapies. While...

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Head and Neck

The treatment of advanced melanoma.

 

Gaining momentum: New options and opportunities for the treatment of advanced melanoma.Authors: Michielin O, Hoeller CAbstract Before 2011, patients with advanced or metastatic melanoma had a particularly poor long-term prognosis. Since traditional treatments failed to confer a survival benefit,...

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Head and Neck

Targeted therapies in advanced differentiated thyroid cancer.

 

Authors: Carneiro RM, Carneiro BA, Agulnik M, Kopp PA, Giles FJAbstract Differentiated thyroid cancer is the most common endocrine malignancy, and its incidence has been rising rapidly over the past 10years. Although most patients with this disease have an excellent prognosis, a subset develops...

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Head and Neck

PI3K/Akt/mTOR: A promising therapeutic target for non-medullary thyroid carcinoma.

 

Authors: Petrulea MS, Plantinga TS, Smit JW, Georgescu CE, Netea-Maier RTAbstractThyroid carcinoma (TC) is the most common endocrine malignancy. The pathogenesis of TC is complex and involves multiple genetic events that lead to activation of oncogenic pathways such as the MAP kinase (MAPK) pathway...

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Head and Neck

Increased radiosensitivity of HPV-positive head and neck cancers: Molecular basis and therapeutic perspectives.

 

Cancer Treat Rev. 2015 Oct 13;Authors: Mirghani H, Amen F, Tao Y, Deutsch E, Levy AAbstract Human papillomavirus driven head and neck squamous cell carcinoma (HNSCC), particularly oropharyngeal squamous cell carcinoma (OPSCC), are characterized by a significant survival advantage over their HPV-negative...

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Head and Neck

Tongue cancer during pregnancy: Surgery and more, a multidisciplinary challenge.

 

Crit Rev Oncol Hematol. 2015 Oct 9;Authors: Tagliabue M, Elrefaey SH, Peccatori F, Favia G, Navach V, Pignataro L, Capaccio P, Venturino M, Tredici S, Alterio D, Mosca F, Pugni L, Scarfone G, Cossu Rocca M, Calabrese LAbstract No international guidelines are available for the treatment of oral...

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Head and Neck

Set-up errors and planning margins in planar and CBCT image-guided radiotherapy using three different imaging systems: A clinical study for prostate and head-and-neck cancer.

 

Phys Med. 2015 Oct 14;Authors: Dzierma Y, Beyhs M, Palm J, Niewald M, Bell K, Nuesken F, Licht N, Rübe CAbstract PURPOSE: The purpose of this work is to compare the positioning accuracy achieved by three different imaging techniques and planar vs. CBCT imaging for two common IGRT indications....

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Head and Neck

BDNF in Lower Brain Parts Modifies Auditory Fiber Activity to Gain Fidelity but Increases the Risk for Generation of Central Noise After Injury.

 

Mol Neurobiol. 2015 Oct 17;Authors: Chumak T, Rüttiger L, Lee SC, Campanelli D, Zuccotti A, Singer W, Popelář J, Gutsche K, Geisler HS, Schraven SP, Jaumann M, Panford-Walsh R, Hu J, Schimmang T, Zimmermann U, Syka J, Knipper MAbstract For all sensory organs, the establishment of spatial and...

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Head and Neck

Cross-activation and Detraining Effects of Tongue Exercise in Aged Rats.

 

Behav Brain Res. 2015 Oct 15;Authors: Schaser AJ, Ciucci MR, Connor NPAbstract Voice and swallowing deficits can occur with aging. Tongue exercise paired with a swallow may be used to treat swallowing disorders, but may also benefit vocal function due to cross-system activation effects. It is...

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Head and Neck

Effectiveness of an (18)F-FDG-PET based strategy to optimize the diagnostic trajectory of suspected recurrent laryngeal carcinoma after radiotherapy: The RELAPS multicenter randomized trial.

 

Radiother Oncol. 2015 Oct 15;Authors: de Bree R, van der Putten L, van Tinteren H, Wedman J, Oyen WJ, Janssen LM, van den Brekel MW, Comans EF, Pruim J, Takes RP, Hobbelink MG, Valdés Olmos R, van der Laan BF, Boers M, Hoekstra OS, Leemans CRAbstract PURPOSE: The purpose of this study is to evaluate...

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Head and Neck

Validation of the total dysphagia risk score (TDRS) in HNC

 

Validation of the total dysphagia risk score (TDRS) in head and neck cancer patients in a conventional and a partially accelerated radiotherapy scheme.Radiother Oncol. 2015 Oct 15;Authors: Nevens D, Deschuymer S, Langendijk JA, Daisne JF, Duprez F, De Neve W, Nuyts SAbstract BACKGROUND AND PURPOSE:...

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Head and Neck

Pituitary Glioblastoma

 

Iran J Cancer Prev. 2015Authors: Anvari K, Samini F, Faraji M, Khooei A, Ghiasi T, Dehghan PAbstract INTRODUCTION: Pituitary adenomas have been the most common sellaturcica tumors. There have been many unusual types of pituitary tumors that might neglect by radiologists and clinicians. One of...

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Head and Neck

Association of Systemic Anaplastic Large Cell Lymphoma and Active Toxoplasmosis in a Child.

 

Iran J Cancer Prev. 2015Authors: Sayyahfar S, Karimi A, Gharib A, Fahimzad AAbstract INTRODUCTION: Anaplastic large cell lymphoma is a subset of non-Hodgkin lymphoma and an unusual disease in children. CASE PRESENTATION: Herein we have reported a 7- year- old girl with a large necrotic...

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Head and Neck

Erectile Dysfunction in Patients with Obstructive Sleep Apnea

 

Low Quality of Life and Depressive Symptoms as an Independent Risk Factor for Erectile Dysfunction in Patients with Obstructive Sleep Apnea.J Sex Med. 2015 Oct 19;Authors: Jeon YJ, Yoon DW, Han DH, Won TB, Kim DY, Shin HWAbstract INTRODUCTION: Accumulating evidence indicates that obstructive...

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Head and Neck

Epidemiological Evaluation of Head and Neck Sarcomas

 

Epidemiological Evaluation of Head and Neck Sarcomas in Iran (the Study of 105 Cases Over 13 Years).Iran J Cancer Prev. 2015Authors: Alishahi B, Kargahi N, Homayouni SAbstract BACKGROUND: Head and neck sarcomas are exceedingly rare and they include 4% - 10% of all sarcomas and less than 1% of...

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Head and Neck

Sentinel lymph node biopsy in Merkel cell carcinoma

 

Sentinel lymph node biopsy in Merkel cell carcinoma: a 15 year institutional experience and statistical analysis of 721 reported cases.Br J Dermatol. 2015 Oct 19;Authors: Gunaratne DA, Howle JR, Veness MJAbstract Merkel cell carcinoma (MCC) is a rare aggressive cutaneous neuroendocrine malignancy...

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Head and Neck

An evaluation of olfactory function in adults with gastro-esophageal reflux disease.

 

Acta Otolaryngol. 2015 Oct 19;:1-5Authors: Günbey E, Gören İ, Ünal R, Yılmaz MAbstract CONCLUSION: To the best of the authors' knowledge, this study is the first to evaluate the olfactory function of adult patients diagnosed with GERD. The results revealed that adults with GERD have diminished...

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Head and Neck

Audiologic evaluation of vestibular schwannoma and other cerebellopontine angle tumors.

 

Acta Otolaryngol. 2015 Oct 19;:1-5Authors: Kim SH, Lee SH, Choi SK, Lim YJ, Na SY, Yeo SGAbstract CONCLUSION: Otologic accompanying symptoms, audiogram patterns, and hearing levels according to tumor size differed in patients with CPA tumors classified as VS and non-VS types. OBJECTIVES:...

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Head and Neck

Clinical characteristics and prognosis of low frequency sensorineural hearing loss without vertigo.

 

Acta Otolaryngol. 2015 Oct 19;:1-5Authors: Jung AR, Kim MG, Kim SS, Kim SH, Geun SYAbstract CONCLUSION: Factors prognostic of recovery from low frequency sensorineural hearing loss without vertigo are co-occurrence of tinnitus, PTA determined hearing level on the affected side before treatment...

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Head and Neck

Clinical evaluation of the xDP output compression strategy for cochlear implants.

 

Eur Arch Otorhinolaryngol. 2015 Oct 17;Authors: Bozorg-Grayeli A, Guevara N, Bebear JP, Ardoint M, Saaï S, Hoen M, Gnansia D, Romanet P, Lavieille JPAbstract Technological advances in the domain of digital signal processing adapted to cochlear implants (CI) are partially responsible for the ever-improving...

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Head and Neck

Human papilloma virus detection and typing

 

 Human papilloma virus detection and typing in 334 lung cancer patients.Authors: Sagerup CM, Nymoen DA, Halvorsen AR, Lund-Iversen M, Helland A, Brustugun OTAbstract BACKGROUND: Unlike cervical, anogenital and oropharyngeal cancers, where high-risk human papillomavirus (hrHPV) has long been known...

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Head and Neck

European reference values for the quality of life questionnaire EORTC QLQ-C30: Results of a German investigation and a summarizing analysis of six European general population normative studies.

 

 Authors: Hinz A, Singer S, Brähler EAbstract BACKGROUND: The aims of this study are to present the results of a new general population normative study of the quality of life questionnaire EORTC QLQ-C30 and to give European reference values averaged across six studies. METHODS: The empirical...

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Head and Neck

The validity and reliability of the 'Cancer Caregiving Tasks, Consequences and Needs Questionnaire' (CaTCoN).

 

Acta Oncol.Authors: Lund L, Ross L, Petersen MA, Groenvold MAbstract BACKGROUND: Caregivers are often involved in and affected by the patient's disease. The questionnaire 'Cancer Caregiving Tasks, Consequences and Needs Questionnaire' (CaTCoN) was developed to measure caregivers' experiences....

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Head and Neck

Patient selection for whole brain radiotherapy (WBRT)

 

 Patient selection for whole brain radiotherapy (WBRT) in a large lung cancer cohort: Impact of a new Dutch guideline on brain metastases.Acta Oncol.Authors: Hendriks LE, Troost EG, Steward A, Bootsma GP, De Jaeger K, van den Borne BE, Dingemans AMAbstract BACKGROUND: Median survival after diagnosis...

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Head and Neck

CXCL4 mediates tumor regrowth after chemotherapy by suppression of antitumor immunity.

 

Cancer Biol Ther. 2015 Oct 19;:0Authors: Zhang Y, Gao J, Wang X, Deng S, Ye H, Guan W, Wu M, Zhu S, Yu Y, Han WAbstract The recurrence of colorectal cancer after chemotherapy is the leading cause of its high mortality. We propose that elucidating the mechanisms of tumor regrowth after chemotherapy...

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Head and Neck

The accuracy of locating the cricothyroid membrane by palpation

 

The accuracy of locating the cricothyroid membrane by palpation - an intergender study.BMC Anesthesiol.Authors: Campbell M, Shanahan H, Ash S, Royds J, Husarova V, McCaul CAbstract BACKGROUND: The cricothyroid membrane (CTM) is the recommended site of access to the airway during cricothyrotomy...

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Head and Neck

Radionuclide (131)I-labeled multifunctional dendrimers for targeted SPECT imaging and radiotherapy of tumors.

 

Nanoscale. 2015 Oct 19;Authors: Zhu J, Zhao L, Cheng Y, Xiong Z, Tang Y, Shen M, Zhao J, Shi XAbstract We report the synthesis, characterization, and utilization of radioactive (131)I-labeled multifunctional dendrimers for targeted single-photon emission computed tomography (SPECT) imaging and...

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Head and Neck

Surgical management of ventrally based lower cervical (subaxial) meningiomas through the lateral approach: Report on 16 cases.

 

Clin Neurol Neurosurg. 2015 Oct 13;139:152-158Authors: Aboul-Enein HA, Khidr WM, Abdeen KM, Madawi AAAbstract OBJECTIVES: Spinal meningiomas are benign and relatively rare tumors. These tumors present about only 25% of primary spinal tumors. Although spinal meningiomas are considered as slowly...

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Head and Neck

Sinonasal paraganglioma with a different morphology

 

A case of sinonasal paraganglioma with a different morphology: nine-year follow-up.Kulak Burun Bogaz Ihtis Derg. 2015Authors: Aydın S, Karabulut B, Orhan KS, Kılıçaslan I, Değer KAbstract Paragangliomas are very occasionally located in the nasal cavity. In this article, we present a 32-year-old...

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Head and Neck

Atypical presentation in Kimura's disease

 

Kulak Burun Bogaz Ihtis Derg. 2015Authors: Bayır Ö, Karagöz T, Tatar EÇ, Özdek A, Han Ü, Saylam G, Korkmaz MHAbstract Kimura's disease is a rare chronic inflammatory disorder with an unknown etiology which presents with the involvements of salivary glands and subdermal tissue in the head or neck...

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Head and Neck

Giant osteoma with intracranial extension filling sinonasal cavity

 

Kulak Burun Bogaz Ihtis Derg. 2015Authors: Gürsoy M, Karaca Erdoğan N, Dağ F, Başoğlu MS, Rezanko Atasever TAbstract Osteomas are the most frequently observed benign bone tumors of paranasal sinuses. Although they are generally detected by chance during radiological analyses, they may create...

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Head and Neck

[Subjective assessment of olfactory function].

 

Kulak Burun Bogaz Ihtis Derg. 2015Authors: Evren C, Yiğit VB, Çınar FAbstract Of the five senses, the sense of smell is the most complex and unique in structure and organization. As diagnostic and therapeutic modalities are often underdeveloped, the sense of smell has been inadequately studied....

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Head and Neck

Investigation of myringosclerosis development in different grafting materials after myringo-/tympanoplasty.

 

Kulak Burun Bogaz Ihtis Derg. 2015Authors: Çatlı T, Çelik Ç, Demir E, Gür H, Tokat T, Olgun LAbstract OBJECTIVES: This study aims to investigate the prevalence of myringosclerosis in tragal perichondrium (TP) and temporalis fascia (TF) grafts after myringo-/tympanoplasty. PATIENTS AND...

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Head and Neck

Is the time from the onset to the treatment a prognostic indicator for hearing recovery in idiopathic sudden sensorineural hearing loss?

 

Kulak Burun Bogaz Ihtis Derg. 2015Authors: Uysal İÖ, Müderris T, Polat K, Yüce S, Gültürk SAbstract OBJECTIVES: This study aims to investigate whether the time from the onset of symptoms to the start of treatment is a prognostic indicator in patients with idiopathic sudden sensorineural hearing...

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Head and Neck

Efficacy of multimodality approach to sudden hearing loss.

 

Kulak Burun Bogaz Ihtis Derg. 2015Authors: Naiboğllu B, Külekçi S, Sürmeli M, Verim A, Kalaycık Ertugay Ç, İhvan Ö, Şeneldir L, Zer Toros SAbstract OBJECTIVES: This study aims to investigate whether addition of intratympanic steroid (ITS) to systemic steroid and hyperbaric oxygen (HBO) is effective...

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Head and Neck

Does Onodi cell limit the exposure of sella during transsphenoidal pituitary surgery?

 

Kulak Burun Bogaz Ihtis Derg. 2015Authors: İmre A, Pınar E, Yüceer N, Songu M, Olgun Y, Aladağ İAbstract OBJECTIVES: This study aims to evaluate the association between the presence of Onodi cell and sella exposure during endonasal endoscopic transsphenoidal pituitary surgery (EETPS). ...

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Head and Neck

The incidence of facial canal dehiscence in Bell's palsy patients

 

Kulak Burun Bogaz Ihtis Derg. 2015Authors: Demirci Ş, Kurt A, Tüzüner A, Samim EE, Çaylan RAbstract OBJECTIVES: In this study, we compared the incidence of facial canal dehiscence in patients with idiopathic peripheral facial paralysis (Bell's palsy) with a healthy population. PATIENTS...

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Head and Neck

Smell function changes in pregnancy

 

[Evaluation of smell function changes in pregnancy].Kulak Burun Bogaz Ihtis Derg. 2015Authors: Gül A, Yılmaz B, Karababa S, Tuna SF, Özkurt FE, Yaman Yörük N, Topçu İAbstract OBJECTIVES: This study aims to compare the olfactory function changes among pregnant women in varying trimesters and non-pregnant...

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Head and Neck

Nasal polyposis: neutrophil to lymphocyte ratio and platelet to lymphocyte ratio

 

[New predictive parameters of nasal polyposis: neutrophil to lymphocyte ratio and platelet to lymphocyte ratio].Kulak Burun Bogaz Ihtis Derg. 2015Authors: Atan D, Özcan KM, Köseoğlu S, İkincioğulları A, Çetin MA, Ensari S, Dere HAbstract OBJECTIVES: This study aims to investigate the correlations...

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Head and Neck

Deep neck infection

 

Clinical features of deep neck infection: analysis of 77 patients.Kulak Burun Bogaz Ihtis Derg. 2015Authors: Sakarya EU, Kulduk E, Gündoğan O, Soy FK, Dündar R, Kılavuz AE, Özbay C, Eren E, İmre AAbstract OBJECTIVES: This retrospective study aims to detect the prognostic factors which affect...

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Head and Neck

Nasal foreign bodies

 

[Nasal foreign bodies: an analysis of 130 patients].Kulak Burun Bogaz Ihtis Derg. 2015Authors: Memiş M, İlhan E, Ulucanlı S, Yaman H, Güçlü EAbstract OBJECTIVES: This study aims to investigate clinical manifestations and treatment protocols in patients with a diagnosis of nasal foreign bodies....

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Head and Neck

Laryngeal leiomyosarcoma with coexistent tuberculous mediastinal lymphadenopathy.

 

Kulak Burun Bogaz Ihtis Derg. 2015Authors: Yüksel Aslıer NG, Doğan E, Sarıoğlu S, İkiz AÖAbstract Laryngeal leiomyosarcoma is an extremely rare malignancy originating from the smooth muscles of blood vessels. Herein, we present the first case of leiomyosarcoma arising from the glottic area of...

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Head and Neck

Bilateral hypopharyngeal perforations caused by penetrating trauma to the neck.

 

Kulak Burun Bogaz Ihtis Derg. 2015Authors: Özbilen Acar G, Tekin M, Karataş M, Özdamar OİAbstract External laryngeal trauma is a relatively rare-encountered and sometimes life-threatening emergency condition. Recognition of laryngeal injury related to either blunt or penetrating trauma is important...

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Head and Neck

İdiopathic spontaneous tonsillar hemorrhage

 

Kulak Burun Bogaz Ihtis Derg. 2015Authors: Köycü A, Erbek SS, Erbek HS, Boyvat FAbstract Since the advent of antibiotics, major spontaneous tonsillar hemorrhage is extremely rare. The majority of the spontaneous tonsillar hemorrhage events is associated with acute or chronic tonsillitis, coagulopathies,...

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Head and Neck

Odynophagia: infected tracheal diverticulum.

 

A rare cause of odynophagia: infected tracheal diverticulum.Kulak Burun Bogaz Ihtis Derg. 2015Authors: Şahin N, Solak A, Genç BAbstractTracheal diverticulum is a relatively rare lesion. Tracheal diverticula are divided into two subgroups as congenital and acquired with different characteristics and...

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Head and Neck

Tualang honey in reducing post-tonsillectomy pain

 

The effectiveness of Tualang honey in reducing post-tonsillectomy pain.Kulak Burun Bogaz Ihtis Derg. 2015Authors: Abdullah B, Lazim NM, Salim RAbstract OBJECTIVES: This study aims to evaluate the effectiveness of Tualang honey in reducing post-tonsillectomy pain. PATIENTS AND METHODS:...

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Head and Neck

Surgical treatment of choanal polyps.

 

Retrospective analysis of surgical treatment of choanal polyps.Kulak Burun Bogaz Ihtis Derg. 2015Authors: İla K, Topdağ M, Öztürk M, İşeri M, Aydın Ö, Keskin GAbstract OBJECTIVES: This study aims to discuss the efficacy of the surgical method performed in patients with choanal polyp in the light...

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Head and Neck

Necessity of mastoidectomy in patients with chronic otitis media having sclerotic mastoid bone: a retrospective clinical study.

 

Kulak Burun Bogaz Ihtis Derg. 2015Authors: Dündar R, Kulduk E, Soy FK, Yazıcı H, Sakarya EU, Özbay CAbstract OBJECTIVES: This study aims to investigate the efficiency of mastoidectomy during tympanoplasty procedures in patients having sclerotic mastoid bone with dry or dried up tympanic cavity....

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Head and Neck

Study of hearing aid effectiveness and patient satisfaction.

 

Kulak Burun Bogaz Ihtis Derg. 2015Authors: Kayabaşoğlu G, Kaymaz R, Erkorkmaz Ü, Güven MAbstract OBJECTIVES: This study aims to investigate hearing aid using rate, patient satisfaction rate and achievements in social communication of patients by assessing the hearing thresholds before and after...

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Head and Neck

Concurrent medullary and papillary carcinoma of thyroid.

 

Kulak Burun Bogaz Ihtis Derg. 2015Authors: Ateşpare A, Çalış AB, Çelik Ö, Yener N, Vural ÇAbstract Simultaneous occurrence of papillary thyroid carcinoma (PTC) and medullary thyroid carcinoma (MTC) in the same thyroid gland is a rare condition. These tumors derive from different cells; PTC originates...

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Head and Neck

Sinonasal inflammatory myofibroblastic pseudotumor (plasma cell granuloma).

 

Kulak Burun Bogaz Ihtis Derg. 2015Authors: Arpacı RB, Kara T, Özyedek E, Serinsöz E, Vayısoğlu Y, Özgür A, Arpacı T, Özcan CAbstract Inflammatory myofibroblastic pseudotumor (plasma cell granuloma) is a soft tissue lesion consisting of myofibroblasts, mature lymphocytes, histiocytes, plasma cells,...

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Head and Neck

Oncocytoma of the parotid gland complicated by hypercalcemia

 

Kulak Burun Bogaz Ihtis Derg. 2015Authors: Evren C, Demirbilek N, Yiğit VB, Kaur ACAbstract Salivary gland tumors are rare head and neck tumors. The majority of these tumors are benign and include pleomorphic adenoma, monomorphic adenoma, oncocytoma, and papillary cystadenoma lymphomatosum. Oncocytoma...

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Head and Neck

Congenital vomer agenesis

 

Kulak Burun Bogaz Ihtis Derg. 2015Authors: Uçar S, Aydın Ö, Öztürk MAbstract Congenital vomer agenesis is a very rare condition. Usually, it is discovered incidentally. Nasal and otologic diseases accompany the cases. In this article, we report two cases of isolated congenital vomer agenesis...

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Head and Neck

[Foreign body in the submandibular gland: a tooth extraction complication].

 

Kulak Burun Bogaz Ihtis Derg. 2015Authors: Kara M, Yazıcı İ, Dereköy FS, Güçlü OAbstract The head and neck region includes many vital anatomic structures. So, diseases of this region may have a more morbid and mortal course compared to other anatomic regions. In this article, we report a patient...

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Head and Neck

Assessment of patients with nasal polyposis by the neutrophil-to-lymphocyte ratio and eosinophil-to-lymphocyte ratio.

 

Kulak Burun Bogaz Ihtis Derg. 2015Authors: Yenigün AAbstract OBJECTIVES: This study aims to investigate the neutrophil-to-lymphocyte ratio (NLR) and eosinophil-to-lymphocyte ratio (ELR) levels in recurrent and non-recurrent nasal polyposis, and identify how the NLR and ELR reflect the inflammatory...

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Head and Neck

Prevalence of otitis media with effusion among school age children

 

Prevalence of otitis media with effusion among school age children in rural parts of Konya province, Turkey.Kulak Burun Bogaz Ihtis Derg. 2015Authors: Varsak YK, Gül Z, Eryılmaz MA, Arbağ HAbstract OBJECTIVES: This study aims to evaluate the current prevalence of serous otitis media (SOM) among...

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Head and Neck

Parathyroid scintigraphy and minimal invasive surgery in parathyroid adenomas.

 

Kulak Burun Bogaz Ihtis Derg. 2015Authors: Özkul MH, Uyar M, Bayram Ö, Dikmen BAbstract OBJECTIVES: This study aims to identify the diagnostic capacity of the technetium 99m sestamibi scintigraphy with single photon emission computed tomography for localizing parathyroid pathologies. PATIENTS...

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Head and Neck

Foreign body impaction in esophagus

 

Foreign body impaction in esophagus: experiences at Ear-Nose-Throat Clinic in Tuzla, 2003-2013.Kulak Burun Bogaz Ihtis Derg. 2015Authors: Umihanić Š, Brkić F, Umihanić Š, Hodźić SAbstract OBJECTIVES: This study aims to report our experience in the management of foreign body (FB) impaction in...

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Head and Neck

Tinnitus caused by sleep bruxism and temporomandibular joint issues

 

Effects of sleep bruxism related tinnitus on quality of life.Kulak Burun Bogaz Ihtis Derg. 2015Authors: Saltürk Z, Özçelik E, Kumral TL, Çakır O, Kasımoğlu Ş, Atar Y, Yıldırım G, Berkiten G, Göker AE, Uyar YAbstract OBJECTIVES: This study aims to analyze the subjective and objective characteristics...

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Head and Neck

Pediatric cholesteatoma

 

[Our surgical treatment results in pediatric cholesteatoma].Kulak Burun Bogaz Ihtis Derg. 2015 PAuthors: Akdoğan MV, Hızal E, Yılmaz S, Yavuz H, Yılmazer C, Canpolat T, Yılmaz İ, Özlüoğlu LNAbstract OBJECTIVES: This study aims to evaluate surgical techniques and obtained outcomes in pediatric...

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Head and Neck

Schwannoma of external auditory canal

 

A large schwannoma of external auditory canal: an unusual case.Kulak Burun Bogaz Ihtis Derg. 2015Authors: Bakshi SS, Shankar K, Parida PKAbstract A 49-year-old female patient presented with mass occluding her external auditory meatus. Surgical exploration revealed that the mass eroded the bony...

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Head and Neck

Multiple primary malignant paraganglioma of the head and neck with lymph node metastasis.

 

Kulak Burun Bogaz Ihtis Derg. 2015Authors: Yetişer S, Ramadan SAbstract Paragangliomas of the head and neck are usually benign tumors. Malignant form is quite rare and criteria for malignancy are not clear. Clinical, biochemical and histological features of malignant forms are not sufficient...

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Head and Neck

Unusual foreign body in the larynx: a bee.

 

Kulak Burun Bogaz Ihtis Derg. 2015Authors: İlhan E, Yaman H, Dost B, Köse GA, Yaman HAbstract Foreign body lodgement in the larynx is a rare situation. Our review of the literature revealed no living foreign body in larynx except for laryngeal leeches and anisakiasis. In this article, we report...

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Head and Neck

Recurrent glomangiopericytoma.

 

An unusual mass of nasal cavity: recurrent glomangiopericytoma.Kulak Burun Bogaz Ihtis Derg. 2015Authors: Gökdoğan O, Demirhan B, Köybaşıoğlu A, İleri FAbstract Hemangiopericytomas are rare tumors of sinonasal region. In this article, we described a case of recurrent mass in right nasal cavity...

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Malignant eccrine spiradenoma of the external ear.

 

Kulak Burun Bogaz Ihtis Derg. 2015Authors: Biçer YÖ, Köybaşı S, Tezcan E, Yılmaz FAbstract Eccrine spiradenoma is a benign tumor of sweat gland origin. Malignant eccrine spiradenoma is a rare neoplasm which almost always arises from a pre-existing spiradenoma lesion. In this article, we present...

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Atrophic rhinitis caused by Cedecea davisae with accompanying mucocele.

 

Kulak Burun Bogaz Ihtis Derg. 2015Authors: Bayır Ö, Yıldırım GA, Saylam G, Yüksel E, Özdek A, Korkmaz MHAbstract Atrophic rhinitis is a chronic inflammatory disease characterized by progressive atrophy of nasal mucosa. Cedecea davisae, a rare pathogen, is a new member of Enterobacteriaceae family....

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EP-DWI MRI at differentiation of cholesteatoma and granulation tissue in patients with chronic suppurative otitis media].

 

Kulak Burun Bogaz Ihtis Derg. 2015 Sep-Oct;25(5):255-65Authors: Tuzcu G, Yardımcı AH, Turna Ö, Göner RE, Acıoğlu EAbstract OBJECTIVES: This study aims to report the significance of echo-planar diffusion-weighted imaging (EP-DWI) in preoperative magnetic resonance imaging of patients with surgically...

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Influence of nasal pack removal on patients' anxiety after septoplasty.

 

Kulak Burun Bogaz Ihtis Derg. 2015 Sep-Oct;25(5):266-70Authors: Şahin C, İmer Aras HAbstract OBJECTIVES: This study aims to investigate the effects of the removal of Merocel nasal packs on patients' anxiety after septoplasty. PATIENTS AND METHODS: Fifty patients (26 males, 24 females;...

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Head and Neck

Establishment and reliability test of a "Vertigo Council Diagnosis Questionnaire" for patients with chronic vestibular dysfunction: preliminary study.

 

Kulak Burun Bogaz Ihtis Derg. 2015 Sep-Oct;25(5):271-4Authors: Karapolat H, Çelebisoy N, Gökçay F, Bilgen C, Özgen G, Göde S, Kirazlı TAbstract OBJECTIVES: This study aims to establish a "Vertigo Council Diagnosis Questionnaire" for patients with chronic vestibular dysfunction and show the reliability...

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Head and Neck

Pack free septoplasty: functional outcomes and complications.

 

Kulak Burun Bogaz Ihtis Derg. 2015 Sep-Oct;25(5):275-8Authors: Eşki E, Yılmaz İAbstract OBJECTIVES: This study aims to evaluate the functional outcomes and complications of pack free septoplasty in adults. PATIENTS AND METHODS: Forty-nine consecutive patients (35 males, 14 females; mean...

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Head and Neck

Prevalence of benign paroxysmal positional vertigo among motocross racers: a case-control study.

 

Kulak Burun Bogaz Ihtis Derg. 2015 Sep-Oct;25(5):279-83Authors: Hancı D, Altun HAbstract OBJECTIVES: This study aims to investigate the prevalence of benign paroxysmal positional vertigo (BPPV) among motocross racers after cross-country up and downhill activities. PATIENTS AND METHODS:...

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Head and Neck

[Impact of markedly nasal septal deviation on 24-hour rhythm Holter findings].

 

Kulak Burun Bogaz Ihtis Derg. 2015 Sep-Oct;25(5):284-8Authors: Derin S, Akın F, Şahan M, Altun İ, Şahin C, Eliçora SŞAbstract OBJECTIVES: This study aims to investigate any impact of nasal septal deviations on cardiac arrhythmias and heart rates by performing 24-hour rhythm Holter analysis before...

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Head and Neck

[The relationship between platelet count and mean platelet volume with obstructive sleep apnea syndrome].

 

Kulak Burun Bogaz Ihtis Derg. 2015 Sep-Oct;25(5):289-94Authors: Atan D, Sazak Kundi FC, Özcan KM, Dere HAbstract OBJECTIVES: This study aims to investigate the relationship between platelet count and mean platelet volume (MPV) with obstructive sleep apnea syndrome (OSAS). PATIENTS AND...

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Rhino-orbito-cerebral mucormycosis

 

[Rhino-orbito-cerebral mucormycosis: two case reports in the light of the literature].Kulak Burun Bogaz Ihtis Derg. 2015 Sep-Oct;25(5):295-301Authors: Kara M, Erdoğan H, Toroslu T, Akçalı A, Tatman Okun M, Reşorlu M, Dereköy FSAbstract Rhino-orbito-cerebral mucormycosis is an acute onset and...

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Head and Neck

Adenoid cystic carcinoma of the accessory parotid gland.

 

Kulak Burun Bogaz Ihtis Derg. 2015 Sep-Oct;25(5):302-5Authors: Baklacı D, Güngör V, Özcan M, Yılmaz YF, Ünal A, Çolak AAbstract Accessory parotid gland is a small salivary gland tissue separated from main part of parotid gland. It is located on the masseter muscle anterior to the Stensen's duct....

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Head and Neck

Submandibular hydatid cyst

 

A rare, incidental submandibular hydatid cyst.Kulak Burun Bogaz Ihtis Derg. 2015 Sep-Oct;25(5):306-9Authors: Doğan M, Polat H, Ayyıldız Ö, Güreli MAbstract Hydatid cyst disease is a parasitic infestation caused by Echinococcus granulosus. It is transmitted via oral ingestion of eggs excreted...

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Head and Neck

Hyoid osteoradionecrosis accompanied by candida infection.

 

Kulak Burun Bogaz Ihtis Derg. 2015 Sep-Oct;25(5):310-4Authors: Yavaş G, Kara Gedik G, Çolpan B, Ata Ö, Öztürk K, Sarı OAbstract Osteoradionecrosis of the hyoid bone is a rare complication of therapeutic irradiation performed for head and neck cancer. In this article, we present a 52-year-old...

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Head and Neck

[Submucosal lingual schwannoma].

 

Kulak Burun Bogaz Ihtis Derg. 2015 Sep-Oct;25(5):315-8Authors: Ulusoy B, Bozdemir K, Ersoy Çallıoğlu E, Kutluhan A, Korkmaz MHAbstract Schwannoma or neurilemmoma is a slow growing, solitary, and encapsulated benign tumor originating from Schwann cells of the peripheral nerves. Lingual schwannomas...

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Head and Neck

Prevalence of benign paroxysmal positional vertigo among motocross racers: a case-control study.

 

Kulak Burun Bogaz Ihtis Derg. 2015 Sep-Oct;25(5):279-83Authors: Hancı D, Altun HAbstract OBJECTIVES: This study aims to investigate the prevalence of benign paroxysmal positional vertigo (BPPV) among motocross racers after cross-country up and downhill activities. PATIENTS AND METHODS:...

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The status of early identification and early intervention in autism spectrum disorders in lower- and middle-income countries.

 

Int J Speech Lang Pathol.Authors: Samms-Vaughan MEAbstract There is limited information on autism spectrum disorders from lower- and middle-income countries (LMIC). This paper reviews the status of early identification and early intervention for autism spectrum disorders in response to the article...

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Child and setting characteristics affecting the adult talk directed at preschoolers with autism spectrum disorder in the inclusive classroom.

 

Autism. 2015Authors: Irvin DW, Boyd BA, Odom SLAbstract Difficulty with social competence is a core deficit of autism spectrum disorder. Research on typically developing children and children with disabilities, in general, suggests the adult talk received in the classroom is related to their...

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How justice can affect jury: training abstract words promotes generalisation to concrete words in patients with aphasia.

 

Authors: Sandberg C, Kiran SAbstract Developing language treatments that not only improve trained items but also promote generalisation to untrained items is a major focus in aphasia research. This study is a replication and extension of previous work which found that training abstract words...

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Factor analysis of auto-associative neural networks with application in speaker verification.

 

IEEE Trans Neural Netw Learn Syst.Authors: Garimella S, Hermansky HAbstract Auto-associative neural network (AANN) is a fully connected feed-forward neural network, trained to reconstruct its input at its output through a hidden compression layer, which has fewer numbers of nodes than the dimensionality...

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Acquisition of the stop-spirant alternation in bilingual speaking children

 

Acquisition of the stop-spirant alternation in bilingual Mexican Spanish-English speaking children: theoretical and clinical implications.: Authors: Fabiano-Smith L, Oglivie T, Maiefski O, Schertz JAbstract The purpose of this study was to identify characteristics of typical acquisition of the...

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Enhancing generalisation in biofeedback intervention using the challenge point framework: a case study.

 

Authors: Hitchcock ER, Byun TMAbstract Biofeedback intervention can help children achieve correct production of a treatment-resistant error sound, but generalisation is often limited. This case study suggests that generalisation can be enhanced when biofeedback intervention is structured in...

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Cortical encoding of phonemic context during word production.

 

Authors: Mugler EM, Goldrick M, Slutzky MWAbstract Brain-computer interfaces that directly decode speech could restore communication to locked-in individuals. However, decoding speech from brain signals still faces many challenges. We investigated decoding of phonemes - the smallest separable...

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Did I say dog or cat? A study of semantic error detection and correction in children.

 

J Exp Child Psychol. 2015 Oct 15;142:36-47Authors: Hanley JR, Cortis C, Budd MJ, Nozari NAbstract Although naturalistic studies of spontaneous speech suggest that young children can monitor their speech, the mechanisms for detection and correction of speech errors in children are not well understood....

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Social deprivation and hospital admission rates, length of stay and readmissions in emergency medical admissions.

 

Eur J Intern Med. 2015 Oct 14;Authors: Cournane S, Byrne D, Conway R, O'Riordan D, Coveney S, Silke BAbstract BACKGROUND: Patients from deprived backgrounds have a higher in-patient mortality following an emergency medical admission. How deprivation relates to the admission or readmission incidence...

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Risk factors for the recurrence of post-semicircular canal benign paroxysmal positional vertigo after canalith repositioning.

 

J Neurol. 2015 Oct 17;Authors: Su P, Liu YC, Lin HCAbstract This retrospective study was conducted to determine the relationship between variable factors and the recurrence rate of post-semicircular canal benign paroxysmal positional vertigo (PSC-BPPV) after canalith repositioning procedure (CRP)....

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Fiducial markers act as visible surrogates of tumor position during image-guided radiotherapy

 

Multimodality guidance for accurate bronchoscopic insertion of fiducial markers.: Authors: Steinfort DP, Siva S, Kron T, Chee RR, Ruben JD, Ball DL, Irving LBAbstract INTRODUCTION: Fiducial markers act as visible surrogates of tumor position during image-guided radiotherapy. Marker placement...

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Vitamin and carotenoid intake and risk of head-neck cancer subtypes

 

Vitamin and carotenoid intake and risk of head-neck cancer subtypes in the Netherlands Cohort Study.: Authors: de Munter L, Maasland DH, van den Brandt PA, Kremer B, Schouten LJAbstract BACKGROUND: Head and neck cancer (HNC) is the seventh most-common type of cancer worldwide. Evidence regarding...

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Cutaneous manifestations in patients with mastocytosis

 

Cutaneous manifestations in patients with mastocytosis: Consensus report of the European Competence Network on Mastocytosis; the American Academy of Allergy, Asthma & Immunology; and the European Academy of Allergology and Clinical Immunology.J Allergy Clin Immunol. 2015 Oct 15;Authors: Hartmann...

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Combined Persistent Fetal Vasculature: A Classification Based on High-Resolution B-Mode Ultrasound and Color Doppler Imaging.

 

Ophthalmology. 2015 Oct 15;Authors: Hu A, Pei X, Ding X, Li J, Li Y, Liu F, Li Z, Zhan Z, Lu LAbstract PURPOSE: The purpose of this study was to classify combined persistent fetal vasculature (PFV) on the basis of the ultrasonographic and Doppler characteristics. The potential clinical significance...

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The peculiar economics of life-extending therapies: a review of costing methods in health economic evaluations in oncology.

 

Expert Rev Pharmacoecon Outcomes Res. 2015 Oct 19;:1-10Authors: Olchanski N, Zhong Y, Cohen JT, Saret C, Bala M, Neumann PJAbstractPublished literature lacks consensus, and most guidelines lack definitive recommendations as to whether cost-effectiveness analyses (CEAs) should include all "future" costs...

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A tocotrienol-enriched formulation protects against radiation-induced changes in cardiac mitochondria without modifying late cardiac function or structure.

 

Authors: Sridharan V, Tripathi P, Aykin-Burns N, Krager KJ, Sharma SK, Moros EG, Melnyk SB, Pavliv O, Hauer-Jensen M, Boerma MAbstract Radiation-induced heart disease (RIHD) is a common and sometimes severe late side effect of radiation therapy for intrathoracic and chest wall tumors. We have...

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Time, dose and ataxia telangiectasia mutated (ATM) status dependency of coding and noncoding RNA expression after ionizing radiation exposure.

 

Authors: Kabacik S, Manning G, Raffy C, Bouffler S, Badie CAbstract Studies of gene expression have proved important in defining the molecular mechanisms of radiation action and identifying biomarkers of ionizing radiation exposure and susceptibility. The full transcriptional response to radiation...

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Head and Neck

The major DNA repair pathway after both proton and carbon-ion radiation is NHEJ, but the HR pathway is more relevant in carbon ions.

 

Authors: Gerelchuluun A, Manabe E, Ishikawa T, Sun L, Itoh K, Sakae T, Suzuki K, Hirayama R, Asaithamby A, Chen DJ, Tsuboi KAbstract The purpose of this study was to identify the roles of non-homologous end-joining (NHEJ) or homologous recombination (HR) pathways in repairing DNA double-strand...

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Head and Neck

Energy metabolism in a matched model of radiation resistance for head and neck squamous cell cancer.

 

Authors: Mims J, Bansal N, Bharadwaj MS, Chen X, Molina AJ, Tsang AW, Furdui CMAbstract While radiation therapy is commonly used for treating cancer, radiation resistance can limit long-term control of the disease. In this study, we investigated the reprogramming of the energy metabolism in...

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Effect of dose rate on residual γ-H2AX levels and frequency of micronuclei in X-irradiated mouse lymphocytes.

 

Authors: Turner HC, Shuryak I, Taveras M, Bertucci A, Perrier JR, Chen C, Elliston CD, Johnson GW, Smilenov LB, Amundson SA, Brenner DJAbstract The biological risks associated with low-dose-rate (LDR) radiation exposures are not yet well defined. To assess the risk related to DNA damage, we...

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NFκB and Survivin-Mediated Radio-Adaptive Response.

 

Authors: Grdina DJ, Murley JS, Miller RC, Woloschak GE, Li JJAbstract A survivin-mediated radio-adaptive response was induced in SA-NH murine sarcoma cells following activation of nuclear transcription factor κB (NFκB) by very low doses of ionizing radiation of 5, 20 or 100 mGy. SA-NH cells...

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Mortality from Circulatory System Diseases among Uranium Miners

 

Mortality from Circulatory System Diseases among French Uranium Miners: A Nested Case-Control Study.: Authors: Drubay D, Caër-Lorho S, Laroche P, Laurier D, Rage EAbstract A significant association has been observed between radon exposure and cerebrovascular disease (CeVD) mortality among French...

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Mitigation of the hematopoietic and gastrointestinal acute radiation syndrome by octadecenyl thiophosphate, a small molecule mimic of lysophosphatidic acid.

 

Authors: Deng W, Kimura Y, Gududuru V, Wu W, Balogh A, Szabo E, Thompson KE, Yates CR, Balazs L, Johnson LR, Miller DD, Strobos J, McCool WS, Tigyi GJAbstract We have previously demonstrated that the small molecule octadecenyl thiophosphate (OTP), a synthetic mimic of the growth factor-like...

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Ionizing radiation-induced cell death is partly caused by increase of mitochondrial reactive oxygen species in normal human fibroblast cells.

 

Authors: Kobashigawa S, Kashino G, Suzuki K, Yamashita S, Mori HAbstract Radiation-induced cell death is thought to be caused by nuclear DNA damage that cannot be repaired. However, in this study we found that a delayed increase of mitochondrial reactive oxygen species (ROS) is responsible for...

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Type 2 Diabetes is a Delayed Late Effect of Whole-Body Irradiation in Nonhuman Primates.

 

 Authors: Kavanagh K, Dendinger MD, Davis AT, Register TC, DeBo R, Dugan G, Cline JMAbstract One newly recognized consequence of radiation exposure may be the delayed development of diabetes and metabolic disease. We document the development of type 2 diabetes in a unique nonhuman primate cohort...

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Human Fibroblasts Exposed to Low- and High-LET Radiation

 

Induction and Repair of DNA DSB as Revealed by H2AX Phosphorylation Foci in Human Fibroblasts Exposed to Low- and High-LET Radiation: Relationship with Early and Delayed Reproductive Cell Death.Authors: Antonelli F, Campa A, Esposito G, Giardullo P, Belli M, Dini V, Meschini S, Simone G, Sorrentino...

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Analyses of ionizing radiation effects in vitro in peripheral blood lymphocytes with Raman spectroscopy.

 

Authors: Maguire A, Vegacarrascal I, White L, McClean B, Howe O, Lyng FM, Meade ADAbstract The use of Raman spectroscopy to measure the biochemical profile of healthy and diseased cells and tissues may be a potential solution to many diagnostic problems in the clinic. Although extensively used...

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Biodosimetry Based on γ-H2AX Quantification and Cytogenetics after Partial- and Total-Body Irradiation during Fractionated Radiotherapy.

 

Authors: Zahnreich S, Ebersberger A, Kaina B, Schmidberger HAbstract The aim of this current study was to quantitatively describe radiation-induced DNA damage and its distribution in leukocytes of cancer patients after fractionated partial- or total-body radiotherapy. Specifically, the impact...

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Connecting radiation-induced bystander effects and senescence to improve radiation response prediction.

 

Authors: Poleszczuk J, Krzywon A, Forys U, Widel MAbstract For the last two decades radiation-induced bystander effects (RIBEs) have attracted significant attention due to their possible implications for radiotherapy. However, despite extensive research, the molecular pathways associated with...

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Hemorrhage trauma increases radiation-induced trabecular bone loss and marrow cell depletion in mice.

 

Authors: Swift JM, Smith JT, Kiang JGAbstract Exposure to high-dose radiation results in deleterious effects on skeletal tissue. However, the effects of combined trauma such as radiation and hemorrhage on skeletal properties have yet to be elucidated. The purpose of this study was to evaluate...

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What level of accuracy is achievable for preclinical dose painting studies on a clinical irradiation platform?

 

Authors: Trani D, Reniers B, Persoon L, Podesta M, Nalbantov G, Leijenaar RT, Granzier M, Yaromina A, Dubois L, Verhaegen F, Lambin PAbstract Advancements made over the past decades in both molecular imaging and radiotherapy planning and delivery have enabled studies that explore the efficacy...

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Spectrum of Radiation-Induced Clustered Non-DSB Damage - A Monte Carlo Track Structure Modeling and Calculations.

 

Authors: Watanabe R, Rahmanian S, Nikjoo HAbstract The aim of this report is to present the spectrum of initial radiation-induced cellular DNA damage [with particular focus on non-double-strand break (DSB) damage] generated by computer simulations. The radiation types modeled in this study were...

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Pediatric cranial radiation therapy : Treatment age, dose and sex determine neuroanatomical outcome in irradiated juvenile mice.

 

Authors: de Guzman AE, Gazdzinski LM, Alsop RJ, Stewart JM, Jaffray DA, Wong CS, Nieman BJAbstract Pediatric cranial radiation therapy can induce long-term neurocognitive deficits, the risk and severity of these deficits are amplified in females and in those individuals exposed at a younger...

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Head and Neck

Cellular and molecular mechanisms underlying oxygen-dependent radiosensitivity.

 

Authors: Liu C, Lin Q, Yun ZAbstract Molecular oxygen has long been recognized as a powerful radiosensitizer that enhances the cell-killing efficiency of ionizing radiation. Radiosensitization by oxygen occurs at very low concentrations with the half-maximum radiosensitization at approximately...

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Radiation-induced sialadenitis : Effect of Phenylephrine Pretreatment on the Expressions of Aquaporin 5 and c-Jun N-Terminal Kinase

 

Authors: Han L, Wang L, Zhang F, Liu KJ, Xiang BAbstract Radiotherapy for malignant tumors of the head and neck commonly leads to radiation-induced sialadenitis as a result of radiation-induced salivary gland dysfunction. We demonstrated previously that phenylephrine could protect the irradiated...

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Investigation of DNA Damage Dose-Response Kinetics after Ionizing Radiation Schemes Similar to CT Protocols.

 

 Authors: Elgart SR, Bostani M, Mok KC, Adibi A, Ruehm S, Enzmann D, McNitt-Gray M, Iwamoto KSAbstract Although there has been extensive research done on the biological response to doses of ionizing radiation relevant to radiodiagnostic procedures, very few studies have examined radiation schemes...

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HIF-1 Alpha Regulates the Response of Primary Sarcomas to Radiation Therapy through a Cell Autonomous Mechanism.

 

Authors: Zhang M, Qiu Q, Li Z, Sachdeva M, Min H, Cardona DM, DeLaney TF, Han T, Ma Y, Luo L, Ilkayeva OR, Lui K, Nichols AG, Newgard CB, Kastan MB, Rathmell JC, Dewhirst MW, Kirsch DGAbstract Hypoxia is a major cause of radiation resistance, which may predispose to local recurrence after radiation...

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Time and Cell Type Dependency of Survival Responses in Co-cultured Tumor and Fibroblast Cells after Exposure to Modulated Radiation Fields.

 

Authors: Butterworth KT, McMahon SJ, McKee JC, Patel G, Ghita M, Cole AJ, McGarry CK, O'Sullivan JM, Hounsell AR, Prise KMAbstract Advanced radiotherapy techniques such as intensity-modulated radiation therapy (IMRT) achieve high levels of conformity to the target volume through the sequential...

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The International Nuclear Workers Study (INWORKS)

 

Dose Estimation for a Study of Nuclear Workers in France, the United Kingdom and the United States of America: Methods for the International Nuclear Workers Study (INWORKS).: Authors: Thierry-Chef I, Richardson DB, Daniels RD, Gillies M, Hamra GB, Haylock R, Kesminiene A, Laurier D, Leuraud K, Moissonnier...

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Local Heart Irradiation : Glutathione S-transferase alpha 4 (GSTA4-4) protection against cardiac function

 

Effects of Local Heart Irradiation in a Glutathione S-Transferase Alpha 4-Null Mouse Model.: Authors: Boerma M, Singh P, Sridharan V, Tripathi P, Sharma S, Singh SPAbstract Glutathione S-transferase alpha 4 (GSTA4-4) is one of the enzymes responsible for the removal of 4-hydroxynonenal (4-HNE),...

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Nuclear Workers Exposed to External Ionizing Radiation.

 

Cancer Mortality through 2005 among a Pooled Cohort of U.S. Nuclear Workers Exposed to External Ionizing Radiation.: Authors: Schubauer-Berigan MK, Daniels RD, Bertke SJ, Tseng CY, Richardson DBAbstract UNLABELLED: Nuclear workers worldwide have been studied for decades to estimate associations...

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Microbiota-induced intestinal sub-symptomatic inflammationtricted or Conventional Intestinal Microbiota Composition Predisposing to Risk for High-LET Radiation Injury?

 

Evidence from Animal Models: Is a Restricted or Conventional Intestinal Microbiota Composition Predisposing to Risk for High-LET Radiation Injury?: Authors: Maier I, Schiestl RHAbstract Intestinal microbiota affect cell responses to ionizing radiation at the molecular level and can be linked...

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MRI-Tracked Tumor Vascular Changes in the Hours after Single-Fraction Irradiation.

 

Authors: Brown SL, Nagaraja TN, Aryal MP, Panda S, Cabral G, Keenan KA, Elmghirbi R, Mikkelsen T, Hearshen D, Knight RA, Wen N, Kim JH, Ewing JRAbstract The purpose of this study was to characterize changes in tumor vascular parameters hours after a single radiation exposure in an orthotopic...

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Ciprofloxacin Therapy Results in Mitigation of ATP Loss after Irradiation Combined with Wound Trauma: Preservation of Pyruvate Dehydrogenase and Inhibition of Pyruvate Dehydrogenase Kinase 1.

 

Authors: Swift JM, Smith JT, Kiang JGAbstract Ionizing radiation exposure combined with wound injury increases animal mortalities than ionizing radiation exposure alone. Ciprofloxacin (CIP) is in the fluroquinolone family of synthetic antibiotic that are available from the strategic national...

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Leukocyte growth factors (LGF),such as Pegfilgrastim Improves Survival of Lethally Irradiated Nonhuman Primates.

 

Authors: Hankey KG, Farese AM, Blaauw EC, Gibbs AM, Smith CP, Katz BP, Tong Y, Prado KL, MacVittie TJAbstract Leukocyte growth factors (LGF), such as filgrastim, pegfilgrastim and sargramostim, have been used to mitigate the hematologic symptoms of acute radiation syndrome (ARS) after radiation...

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Radiation Dose-Rate Effects on Gene Expression

 

Radiation Dose-Rate Effects on Gene Expression in a Mouse Biodosimetry Model.: Authors: Paul S, Smilenov LB, Elliston CD, Amundson SAAbstract In the event of a nuclear accident or radiological terrorist attack, there will be a pressing need for biodosimetry to triage a large, potentially exposed...

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Early-life irradiation may have long-term consequences on the immune system, leading to an altered antiviral response

 

Examining the Effects of External or Internal Radiation Exposure of Juvenile Mice on Late Morbidity after Infection with Influenza A.: Authors: Misra RS, Johnston CJ, Groves AM, DeDiego ML, St Martin J, Reed C, Hernady E, Miller JN, Love T, Finkelstein JN, Williams JPAbstract A number of investigators...

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Serum Amyloid A as a Biomarker for Radiation Exposure.

 

Authors: Sproull M, Kramp T, Tandle A, Shankavaram U, Camphausen KAbstract There is a need for minimally invasive biomarkers that can accurately and quickly quantify radiation exposure. Radiation-responsive proteins have applications in clinical medicine and for mass population screenings after...

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Defining Blood Processing ParamThe direct measurement of radiation-induced γ-H2AX foci in peripheral blood lymphocyteseters for Optimal Detection of γ-H2AX Foci: A Small Blood Volume Method.

 

Defining Blood Processing Parameters for Optimal Detection of γ-H2AX Foci: A Small Blood Volume Method.: Authors: Wojewodzka M, Sommer S, Kruszewski M, Sikorska K, Lewicki M, Lisowska H, Wegierek-Ciuk A, Kowalska M, Lankoff AAbstract Biodosimetric methods used to measure the effects of radiation...

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High linear energy transfer (LET) α particles are important with respect to the carcinogenic risk associated with human exposure to ionizing radiation

 

Variation in RBE for Survival of V79-4 Cells as a Function of Alpha-Particle (Helium Ion) Energy.: Authors: Tracy BL, Stevens DL, Goodhead DT, Hill MAAbstract High linear energy transfer (LET) α particles are important with respect to the carcinogenic risk associated with human exposure to ionizing...

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The Techa River Cohort have established associations between radiation dose and the occurrence of solid cancers and leukemia (non-CLL)

 

Solid Cancer Incidence in the Techa River Incidence Cohort: 1956-2007.: Authors: Davis FG, Yu KL, Preston D, Epifanova S, Degteva M, Akleyev AVAbstract Previously reported studies of the Techa River Cohort have established associations between radiation dose and the occurrence of solid cancers...

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Subject-Based versus Population-Based Care after Radiation Exposure.

 

Authors: Yu JZ, Lindeblad M, Lyubimov A, Neri F, Smith B, Szilagyi E, Halliday L, MacVittie T, Nanda J, Bartholomew AAbstract In a mass casualty radiation event situation, individualized therapy may overwhelm available resources and feasibility issues suggest a need for the development of population-based...

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Radiation Effects Investigations Based on Atmospheric Radiation Model (ATMORAD) Considering GEANT4 Simulations of Extensive Air Showers and Solar Modulation Potential.

 

Authors: Hubert G, Cheminet AAbstract The natural radiative atmospheric environment is composed of secondary cosmic rays produced when primary cosmic rays hit the atmosphere. Understanding atmospheric radiations and their dynamics is essential for evaluating single event effects, so that radiation...

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A Case Report: Cytogenetic Dosimetry after Accidental Radiation Exposure during (192)Ir Industrial Radiography Testing.

 

Radiat Res. 2015http://www.bioone.org/doi/10.1667/RR14013.1?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3DpubmedAuthors: Beinke C, Ben-Shlomo A, Abend M, Port MAbstract The accidental gamma radiation exposure of an industrial radiography worker and the cytogenetic examination...

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A Mouse Ear Model for Bystander Studies Induced by Microbeam Irradiation.

 

Radiat Res. 2015Authors: Buonanno M, Randers-Pehrson G, Smilenov LB, Kleiman NJ, Young E, Ponnayia B, Brenner DJAbstract Radiation-induced bystander effects have been observed in vitro and in cell and tissue culture models, however, there are few reported studies showing these effects in vivo....

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X-Band Rapid-Scan Electron Paramagnetic Resonance of Radiation-Induced Defects in Tooth Enamel.

 

Radiat Res. 2015Authors: Yu Z, Romanyukha A, Eaton SS, Eaton GRAbstract X-band rapid-scan electron paramagnetic resonance (EPR) spectra from tooth enamel samples irradiated with doses of 0.5, 1 and 10 Gy had substantially improved signal-to-noise relative to conventional continuous wave EPR....

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Thyroid Dose Estimates for a Cohort of Belarusian Children Exposed to (131)I from the Chernobyl Accident: Assessment of Uncertainties.

 

Radiat Res. 2015Authors: Drozdovitch V, Minenko V, Golovanov I, Khrutchinsky A, Kukhta T, Kutsen S, Luckyanov N, Ostroumova E, Trofimik S, Voillequé P, Simon SL, Bouville AAbstractDeterministic thyroid radiation doses due to iodine-131 ((131)I) intake were reconstructed in a previous article for 11,732...

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The Use of X Rays in the Treatment of Bronchial Asthma

 

The Use of X Rays in the Treatment of Bronchial Asthma: A Historical Assessment.Radiat Res. 2015Authors: Calabrese EJ, Dhawan G, Kapoor RAbstract This article provides a historical assessment of the role of X-ray therapy in the treatment of bronchial asthma. This analysis revealed that X-ray...

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Acute Effects of Exposure to (56)Fe and (16)O Particles on Learning and Memory.

 

Radiat Res. 2015Authors: Rabin BM, Poulose SM, Carrihill-Knoll KL, Ramirez F, Bielinski DF, Heroux N, Shukitt-Hale BAbstract Although it has been shown that exposure to HZE particles disrupts cognitive performance when tested 2-4 weeks after irradiation, it has not been determined whether exposure...

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A Single Low Dose of Proton Radiation Induces Long-Term Behavioral and Electrophysiological Changes in Mice.

 

Radiat Res. 2015Authors: Bellone JA, Rudobeck E, Hartman RE, Szücs A, Vlkolinský RAbstract Astronauts traveling outside Earth's magnetosphere risk exposure to charged particle radiation that may cause neurophysiological changes and behavioral deficits. Although proton particles comprise a large...

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Urinary Biomarkers in Nonhuman Primates Exposed to Ionizing Radiation.

 

Global Metabolomic Identification of Long-Term Dose-Dependent Urinary Biomarkers in Nonhuman Primates Exposed to Ionizing Radiation.Radiat Res. 2015Authors: Pannkuk EL, Laiakis EC, Authier S, Wong K, Fornace AJAbstract Due to concerns surrounding potential large-scale radiological events, there...

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Tolerance to Dose Escalation in Minibeam Radiation Therapy Applied to Normal Rat Brain: Long-Term Clinical, Radiological and Histopathological Analysis.

 

: Authors: Prezado Y, Deman P, Varlet P, Jouvion G, Gil S, Le Clec'H C, Bernard H, Le Duc G, Sarun SAbstract The major limitation to reaching a curative radiation dose in radioresistant tumors such as malignant gliomas is the high sensitivity to radiation and subsequent damage of the surrounding...

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Comparison of the Effectiveness of Exposure to Low-LET Helium Particles ((4)He) and Gamma Rays ((137)Cs) on the Disruption