Frontal Sino-Cutaneous Fistula Masquerading as a Basal Cell Carcinoma

xlomafota13 shared this article with you from Inoreader Frontal Sino-Cutaneous Fistula Masquerading as a Basal Cell Carcinoma Via ear nose throat Ear Nose Throat J. 2022 Jan 20:1455613221075235. doi: 10.1177/01455613221075235. Online ahead of print. NO ABSTRACT PMID:35057655 | DOI:10.1177/01455613221075235 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Radioiodination and Purification of [131I]β-CIT and [131I]FP-CIT with an Automated Radiosynthesizer

xlomafota13 shared this article with you from Inoreader Radioiodination and Purification of [<sup>131</sup>I]β-CIT and [<sup>131</sup>I]FP-CIT with an Automated Radiosynthesizer Via radioactive iodine Pharmaceuticals (Basel). 2022 Jan 14;15(1):96. doi: 10.3390/ph15010096. ABSTRACT Dopaminergic transporter (DAT) imaging with single photon emission computed tomography (SPECT) is used to diagnose Parkinson's disease and to differentiate it from other neurodegenerative disorders without presynaptic dopaminergic dysfunction. The radioiodinated tropane alkaloids [123I]FP-CIT and [123I]β-CIT enable the evaluation of the integrity of DATs. Commonly, the labeling o f these compounds is performed by electrophilic substitution of the alkylstannylated precursors with radioactive iodine and following purification by HPLC or solid phase extraction (SPE). This work presents the first radioiodination of β-CIT and FP-CIT with no carrier added [131I]NaI on a Scintomics GRP synthesis module. Free iodine-131 and impurities were removed by SPE over a C-18 Sep-Pak cartridge. We achieved a radiochemical yield of >75% and a radiochemical purity of >98% with both compounds. Our development of an automated synthesis on a commercially available synthesizer ensures robust and efficient labeling of [131I]FP-CIT and [131I]β-CIT starting with low concentrated radioiodine. PMID:35056152 | DOI:10.3390/ph15010096 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

The Clinical Characteristics in Children with Sinonasal Inverted Papilloma: A Case Report and Review of the Literature

xlomafota13 shared this article with you from Inoreader The Clinical Characteristics in Children with Sinonasal Inverted Papilloma: A Case Report and Review of the Literature Via ear nose throat Ear Nose Throat J. 2022 Jan 21:1455613211068567. doi: 10.1177/01455613211068567. Online ahead of print. ABSTRACT Sinonasal inverted papilloma (SNIP) is one of the most common benign epithelial tumors but rarely occurs in children. The case of a 9-year-old Chinese boy, who presented with a left maxillofacial hump, nasal obstruction, and left nasal cavity and maxillary sinus masses under nasal endoscopy, is reported. The lesion was first diagnosed as a sinonasal tumor. However , to our surprise, the mass was determined to be an inverted papilloma after a detailed histological examination. We retrospectively reported the clinical data of this case and reviewed the relevant literatures on SNIP. This report aims to provide new insights into the clinical characteristics in children with SNIP and improve the understanding of this disease. PMID:35060773 | DOI:10.1177/01455613211068567 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Imaging characteristics of hypertrophic pachymeningitis due to ANCA-associated vasculitis

xlomafota13 shared this article with you from Inoreader Imaging characteristics of hypertrophic pachymeningitis due to ANCA-associated vasculitis Via Auris Nasus Larynx Publication date: Available online 21 January 2022 Source: Auris Nasus Larynx Author(s): Taro Takagi, Masahiro Okada, Masashi Nakamura, Takahiro Hanari, Takahiro Nakata, Masato Teraoka, Naohito Hato View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Exploration of chest wall perforator vascular anatomy on standard breast MRI: A potential aid to chest wall perforator flap planning

xlomafota13 shared this article with you from Inoreader Exploration of chest wall perforator vascular anatomy on standard breast MRI: A potential aid to chest wall perforator flap planning Via Journal of plastic, reconstructive & aesthetic surgery : JPRAS J Plast Reconstr Aesthet Surg. 2021 Dec 1:S1748-6815(21)00639-2. doi: 10.1016/j.bjps.2021.11.092. Online ahead of print. ABSTRACT Local chest wall perforator flaps (CWPFs) are a volume replacement technique permitting breast-conserving surgery in patients who otherwise may require a mastectomy. These flaps are based on one or more perforating arteries arising from the lateral chest wall that travel through the soft tissue and into the sub-dermal plexus to perfuse the flap. Examples include the lateral intercostal and lateral thoracic artery perforators (LICAP and LTAP, respectively). Cross-sectional imaging of perforating vessels is not routinely performed, and vessels are mapped pre- and peri-operatively using a hand-held acoustic doppler device. As many breast cancer patients undergo pre-operative MRI scanning for oncological purposes, we investigated the role of MRI in mapping the vascular anatomy to aid with the surgical planning o f CWPFs. We collated data retrospectively on a cohort of breast cancer patients who underwent breast MRI as part of routine pre-operative imaging. Axial 3D high-resolution dynamic contrast-enhanced MRI sequences with multiplanar reconstructions were analysed by a consultant radiologist. The presence and calibre of lateral chest wall perforator vessels were assessed. Fifty patients were suitable for inclusion. A consistent pattern of lateral chest wall vasculature was observed. Forty-eight patients (96%) demonstrated a bilateral lateral thoracic artery (LTA) descending inferiorly along the chest wall with two-thirds of these communicating with perforating intercostal vessels. True independent LICAP vessels were identified in six patients. From our observations, lateral CWPFs are dependent on an intricate intercommunication between intercostal vessels and the LTA which in turn supply perforators to the lateral chest wall donor site. PMID:35063384 | DOI:10.1016/j.bjps.2021.11.092 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Towards decoding selective attention through cochlear implant electrodes as sensors in subjects with contralateral acoustic hearing

xlomafota13 shared this article with you from Inoreader Towards decoding selective attention through cochlear implant electrodes as sensors in subjects with contralateral acoustic hearing Via cortical auditory J Neural Eng. 2022 Jan 21. doi: 10.1088/1741-2552/ac4de6. Online ahead of print. ABSTRACT OBJECTIVES: Focusing attention on one speaker in a situation with multiple background speakers or noise is referred to as auditory selective attention. Decoding selective attention is an interesting line of research with respect to future brain-guided hearing aids or cochlear implants (CIs) that are designed to adaptively adjust sound processing through cortical feedback loops. This study investigates the feasibility of using the electrodes and backward telemetry of a CI to record electroencephalography (EEG). APPROACH: The study population included 6 normal-hearing (NH) listeners and 5 CI users with contralateral acoustic hearing. Cortical auditory evoked potentials (CAEP) and selective attention were recorded using a state-of-the-art high-density scalp EEG and, in the case of CI users, also using two CI electrodes as sensors in combination with t he backward telemetry system of these devices (iEEG). MAIN RESULTS: In the selective attention paradigm with multi-channel scalp EEG the mean decoding accuracy across subjects was 94.8 % and 94.6 % for NH listeners and CI users, respectively. With single-channel scalp EEG the accuracy dropped but was above chance level in 8 to 9 out of 11 subjects, depending on the electrode montage. With the single-channel iEEG, the selective attention decoding accuracy could only be analyzed in 2 out of 5 CI users due to a loss of data in the other 3 subjects. In these 2 CI users, the selective attention decoding accuracy was above chance level. SIGNIFICANCE: This study shows that single-channel EEG is suitable for auditory selective attention decoding, even though it reduces the decoding quality compared to a multi-channel approach. CI-based iEEG can be used for the purpose of recording CAEPs and decoding selective attention. However, the study also points out the need for further tec hnical development for the CI backward telemetry regarding long-term recordings and the optimal sensor positions. PMID:35062007 | DOI:10.1088/1741-2552/ac4de6 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Intractable Bleeding Following an Awake Bedside Injection Laryngoplasty in a Patient on KVAD ECMO

xlomafota13 shared this article with you from Inoreader Intractable Bleeding Following an Awake Bedside Injection Laryngoplasty in a Patient on KVAD ECMO Via Journal of Voice Awake injection laryngoplasty (IL) is becoming increasingly utilized in the inpatient setting, especially as a therapeutic option for patients with vocal fold immobility immediately following cardiothoracic surgery. While prior studies consistently demonstrate complication rates below 3%, significant bleeding has not been reported as a major complication in any awake IL case series. The objective of this report is to highlight a case of intractable bleeding following awake inpatient bedside IL in a patient on KVAD (Koji Takeda Ventricular Assist Device) extracorporeal membrane oxygenation (ECMO). View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.