Extracellular matrix for repair of type IV laryngotracheo-esophageal cleft.

Extracellular matrix for repair of type IV laryngotracheo-esophageal cleft.

Int J Pediatr Otorhinolaryngol. 2015 Nov 6;

Authors: Evans AK, Kon ND

Abstract
Type IV laryngotracheo-esophageal cleft (LTEC) extending to the level of the carina presents unique challenges to operative repair, particularly with respect to soft tissue durability. This is the first report of CorMatrix(®) extra-cellular matrix (ECM) material use as an interposition graft in a four-layered LTEC repair. At day seven post-operatively, there was epithelialization along the surface of the trachea. At 3 months, she was stable for tracheotomy. At 6 months, the posterior wall resembled completely native tissue. CorMatrix(®) ECM(®) use intra-operatively and post-operative outcome were both highly satisfactory. No adverse reaction was seen in this case through 12-month follow up.

PMID: 26616544 [PubMed - as supplied by publisher]

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