Nasal angiosarcoma metastatic to the larynx: Case report and systematic review of the literature.

Nasal angiosarcoma metastatic to the larynx: Case report and systematic review of the literature.

Head Neck. 2015 Dec 30;

Authors: Qualls HE, Mitchell RM, Deubner H, Moe KS, Sardesai M

Abstract
BACKGROUND: Laryngeal angiosarcoma is rare and the prognosis is poor. The purpose of this study was to describe the first case of cutaneous angiosarcoma metastatic to the larynx and systematically review all cases of laryngeal angiosarcoma.
METHODS: A 61-year-old man presented with an alar lesion diagnosed as angiosarcoma and was treated with wide local resection and radiation. Six years later, he presented with a laryngeal mass histologically similar to the initial tumor. A systematic review of reported cases of angiosarcoma of the larynx was performed.
RESULTS: Eighteen cases were identified. Mean age of presentation was 64.3 years. Men represented 66.7%. Mean follow-up was 34.1 months. Forty-seven percent died with disseminated disease at a mean of 18.4 months. Our patient did well with serial resection.
CONCLUSION: To the best of our knowledge, this case represents the first documented case of cutaneous angiosarcoma metastatic to the larynx and suggests that serial resection with long-term surveillance may be of benefit in some cases. © 2015 Wiley Periodicals, Inc. Head Neck, 2015.

PMID: 26717551 [PubMed - as supplied by publisher]

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