Mechanically Induced Tunable Pain and Associated Temporomandibular Joint Responses
Development of a Rat Model of via Oral and Maxillofacial Surgery Publication date: January 2016 *Source:*Journal of Oral and Maxillofacial Surgery, Volume 74, Issue 1 Author(s): Sonia Kartha, Timothy Zhou, Eric J. Granquist, Beth A. Winkelstein PurposeAlthough mechanical overloading of the temporomandibular joint (TMJ) is implicated in TMJ osteoarthritis (OA) and orofacial pain, most experimental models of TMJ-OA induce only acute and resolving pain, which do not meaningfully simulate the pathomechanisms of TMJ-OA in patients with chronic pain. The aim of this study was to adapt an ex... περισσότερα »
Single-Dose of Pre-Emptive Pregabalin on Postoperative Pain and Opioid Consumption
Effects of a Single-Dose of Pre-Emptive Pregabalin on Postoperative Pain and Opioid Consumption After Double-Jaw Surgery: A Randomized Controlled Trial via Oral and Maxillofacial Surgery Publication date: January 2016 *Source:*Journal of Oral and Maxillofacial Surgery, Volume 74, Issue 1 Author(s): Ali Ahiskalioglu, İlker İnce, Mehmet Aksoy, Ertan Yalcin, Elif Oral Ahiskalioglu, Adnan Kilinc PurposeThe effect of a single-dose of pre-emptive pregabalin is still unknown, although it is used as an adjuvant in controlling acute postoperative pain. The purpose of this study was to evaluate ... περισσότερα »
Facial Morphology : Temporomandibular Joint Disorders
Temporomandibular Joint Disorders in Patients With Different Facial Morphology. A Systematic Review of the Literature via Oral and Maxillofacial Surgery Publication date: January 2016 *Source:*Journal of Oral and Maxillofacial Surgery, Volume 74, Issue 1 Author(s): Daniele Manfredini, Marzia Segù, Niki Arveda, Luca Lombardo, Giuseppe Siciliani, Alessandro Rossi, Luca Guarda-Nardini PurposeThe present article aimed to review systematically the literature on the relation between facial skeletal structures and temporomandibular joint (TMJ) disorders.Materials and MethodsA systematic search... περισσότερα »
Osteotomies Prepared With Er:YAG Laser
Evaluation of Bone Healing After Osteotomies Prepared With Er:YAG Laser in Contact and Noncontact Modes and Piezosurgery—An Animal Study via Oral and Maxillofacial Surgery Publication date: January 2016 *Source:*Journal of Oral and Maxillofacial Surgery, Volume 74, Issue 1 Author(s): Dragana Gabrić, Marko Blašković, Elizabeta Gjorgijevska, Mitko Mladenov, Blaž Tašič, Ivona Bago Jurič, Ticijana Ban PurposeTo analyze the healing of bone tissue treated with Er:YAG laser contact and noncontact modes of and piezosurgery in a rat model using triangular laser profilometry.Materials and Methods... περισσότερα »
Venous Thromboembolism After Oral Oncologic Surgery
Incidence of Venous Thromboembolism After Oral Oncologic Surgery With Simultaneous Reconstruction via Oral and Maxillofacial Surgery Publication date: January 2016 *Source:*Journal of Oral and Maxillofacial Surgery, Volume 74, Issue 1 Author(s): Yasumasa Kakei, Masaya Akashi, Takumi Hasegawa, Tsutomu Minamikawa, Satoshi Usami, Takahide Komori PurposePatients with oral cancer who undergo resection with simultaneous reconstruction are presumed to be at high risk for developing venous thromboembolism (VTE) according to current criteria. The primary purpose of this retrospective study was ... περισσότερα »
Low-Grade Fibromyxoid Sarcoma of the Maxilla
A Rare Pathology: via Oral and Maxillofacial Surgery Publication date: January 2016 *Source:*Journal of Oral and Maxillofacial Surgery, Volume 74, Issue 1 Author(s): Simon Spalthoff, Martin Bredt, Nils-Claudius Gellrich, Philipp Jehn Low-grade fibromyxoid sarcoma (LGFMS) is a rare tumor with a benign histologic appearance and fully malignant behavior. To date, only 5 cases of LGFMS in the maxillofacial region have been reported. This report describes the case of a 16-year-old boy who was referred to the authors' hospital with an intraosseous myxofibroblastic tumor, probably of the LGF...περισσότερα »
Local Full-Thickness Skin Grafts for Closure of Free Fibular Osteocutaneous Flap Donor Sites
Novel via Oral and Maxillofacial Surgery Publication date: January 2016 *Source:*Journal of Oral and Maxillofacial Surgery, Volume 74, Issue 1 Author(s): You-yuan Wang, Song Fan, Da-ming Zhang, Zhao-yu Lin, Wei-liang Chen, Jin-song Li PurposeThe fibular flap donor site after skin paddle harvest is usually covered with abdominal full-thickness skin grafts. However, this kind of skin graft creates an inevitable third operative area and additional esthetic damage. The aim of this report was to present a novel approach to manage fibular donor site defects using a full-thickness skin graft... περισσότερα »
The vascularized fibula bone graft for reconstruction of the mandible
Feasibility of the vascularized fibula bone graft for reconstruction of the mandible: a cadaveric study: The aim of this study was to assess the feasibility of the unilateral single-barrel vascularized fibula bone graft (VFBG) for the restoration of mandibular defects. Eighty-one dry mandibles and fibulas were used. Each mandible was marked to measure the total mandible length (TML) and maximum defect length (MDL) for each type of defect (HCH, H, L, C, HC, LC, LCL, HCL; Boyd's classification and angle to angle). The fibula length (FL) was measured. The maximum vascularized fibula le... περισσότερα »
Intramuscular innervations of lower leg skeletal muscles: applications in their clinical use in functional..
Switch to one email a week Unsubscribe from daily digest Take advantage of our special Holiday Deal. Upgrade to Feedspot Gold for Lifetime at 89% off. Upgrade Now Surgical and Radiologic Anatomy Remove Intramuscular innervations of lower leg skeletal muscles: applications in their clinical use in functional muscular transfer 18 hours ago . Save . Twitter Abstract Purpose This study aims to investigate nerve distribution patterns of human lower leg skeletal muscles using a modified Sihler's staining method. Meth.. Read More → ScienceDirect Publication: Palaeogeography,... περισσότερα »
Quick Lane Bowl: CMU, Minn. coaches battled health issues – Detroit Free Press
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 46 δευτερόλεπτα
KATV Quick Lane Bowl: CMU, Minn. coaches battled health issues Detroit Free Press Bonamego announced in June that he had cancer in his left tonsil, but he was able to keep coaching his team, and the Chippewas tied atop their division in the Mid-American Conference. They will play in the Quick Lane Bowl against Minnesota […]
Investigation of Cytotoxic T-lymphocyte antigen 4 (CTLA4) Polymorphisms in Gastric Cardia Adenocarcinoma
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 51 δευτερόλεπτα
Abstract To assess the potential effects of Cytotoxic T-lymphocyte antigen 4 (CTLA4) gene polymorphisms on susceptibility to gastric cardia adenocarcinoma (GCA), we genotyped four polymorphisms (rs733618 A>G, rs16840252 C>T, rs231775 G>A and rs3087243 G>A) in CTLA4 and calculated odds ratios (ORs) with the corresponding 95% confidence intervals (95% CIs) for the genotype and allele distributions […]
Blockade of Interlukin-17 restrains the development of acute lung injury
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 51 δευτερόλεπτα
Abstract The acute respiratory distress syndrome (ARDS), a clinical complication of severe acute lung injury (ALI) in humans, is a leading cause of morbidity and mortality in critically ill patients. Here we explored the association between IL-17 and development of ALI using LPS-induced murine model. We found that IL-17 level was elevated in bronchoalveolar lavage […]
Increased B regulatory phenotype in non-metastatic lymph nodes of node positive breast cancer patients
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 51 δευτερόλεπτα
Abstract Tumor draining lymph nodes (TDLNs) are center in orchestrating the immune responses against cancer. The cellularity and lymphocyte subpopulations change in the process of cancer progression and lymph node involvement. B lymphocyte subsets and their function in breast cancer draining lymph nodes have not been well elucidated. Here, we studied the influence of tumor […]
Increased levels of interferon-inducible protein 10 (IP-10) in 22q11.2 Deletion Syndrome
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 51 δευτερόλεπτα
Abstract The 22q11.2 deletion syndrome (22q11.2 DS), also known as DiGeorge syndrome, is a genetic disorder with an estimated incidence of 1:4000 births. These patients may suffer from affection of many organ systems with cardiac malformations, thymic hypoplasia or aplasia, hypoparathyroidism, palate anomalies and psychiatric disorders being the most frequent. The incidence of autoimmune diseases […]
Hämorrhoiden konservativ behandeln oder operieren?
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 51 δευτερόλεπτα
Therapieoptionen Hämorrhoidalleiden zählen zu den häufigen Beschwerden in Industrieländern. Über 95% der Patienten können mit konservativen Maßnahmen versorgt werden. Wann kommt welche der zahlreichen Möglichkeiten für den Einzelnen infrage? from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1RNgEPL via IFTTT
Hämorrhoiden konservativ behandeln oder operieren?
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 54 δευτερόλεπτα
Therapieoptionen Hämorrhoidalleiden zählen zu den häufigen Beschwerden in Industrieländern. Über 95% der Patienten können mit konservativen Maßnahmen versorgt werden. Wann kommt welche der zahlreichen Möglichkeiten für den Einzelnen infrage? from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1RNgEPL via IFTTT
Chemistry in glow discharges of H2 / O2 mixtures. Diagnostics and modelling
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 54 δευτερόλεπτα
Plasma sources science & technology from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Ud5Qby via IFTTT
Ion kinetics in Ar/H2 cold plasmas: the relevance of ArH+
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 54 δευτερόλεπτα
RSC advances from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Ud5PUU via IFTTT
Anemia
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 54 δευτερόλεπτα
Anemia: The condition of having a lower-than-normal number of red blood cells or quantity of hemoglobin. Anemia diminishes the capacity of the blood to carry oxygen. Patients with anemia may feel tired, fatigue easily, appear pale, develop palpitations, and become short of breath. Children with chronic anemia are prone to infections and learning problems. The […]
Chemistry in glow discharges of H2 / O2 mixtures. Diagnostics and modelling
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 54 δευτερόλεπτα
Plasma sources science & technology from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Ud5Qby via IFTTT
Quality Indicators in Pituitary Surgery: A Need for Reliable and Valid assessments. What should be measured?
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 54 δευτερόλεπτα
Abstract Engagement with improving the quality of clinical care is a key component of medical professionalism. Central to Quality Improvement (QI) agenda are the development of valid, reliable and accurate quality metrics. We can’t improve what we don’t measure. Pituitary surgery, which in the 21st century usually means trans-sphenoidal surgery (TSS), is unusual; it is […]
Ion kinetics in Ar/H2 cold plasmas: the relevance of ArH+
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 54 δευτερόλεπτα
RSC advances from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Ud5PUU via IFTTT
Association between lung capacity and abnormal glucose metabolism: Findings from China and Australia
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 54 δευτερόλεπτα
Abstract Objective Restricted pulmonary function is found among people with diabetes. This study aimed to investigate the dose-response relationship between pulmonary function measurements (forced expiratory volume in one second (FEV1) and forced vital capacity (FVC)) and risk of metabolic syndrome (MS) /type 2 diabetes. Methods 1,454 adults in rural Victoria, Australia and 5,824 adults in […]
The importance of knowing the timing within the menstrual cycle in non-menopausal hypertensive women in the diagnostic workup for primary aldosteronism
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 54 δευτερόλεπτα
Abstract We read with interest the paper by Ahmed el al (1), which demonstrates the importance of knowing the timing within the menstrual cycle when a diagnostic test is done for primary aldosteronism in non-menopausal women, reporting greater percentages of positive fludrocortisone suppression tests in the luteal compared to the follicular phase. Interestingly, a positive […]
Response to letter to the Editor
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 54 δευτερόλεπτα
Abstract We thank the authors for their positive and insightful comments. The close agreement between their results and ours certainly adds weight to the findings and conclusions of our study. We also thank them for their proposed explanation concerning the discrepancy in reported results of in vitro studies assessing the effects of progesterone on aldosterone […]
The STAT3 pathway as a therapeutic target in head and neck cancer
The STAT3 pathway as a therapeutic target in head and neck cancer: Barriers and innovations: Proteins of the signal transducer and activator of transcription (STAT) family mediate cellular responses to cytokines and growth factors. Aberrant regulation of the STAT3 oncogene contributes to tumor formation and progression in many cancers, including head and neck squamous cell carcinoma (HNSCC), where hyperactivation of STAT3 is implicated in both treatment resistance and immune escape. There are no oncogenic gain-of-function mutations in HNSCC. Rather, aberrant STAT3 signaling is prima...περισσότερα »
Oral chronic Graft-versus-host disease (cGVHD) outcomes and resource utilization
Oral chronic GVHD outcomes and resource utilization: a subanalysis from the chronic GVHD consortium: Abstract Objectives This study evaluated the extent to which oral chronic graft-versus-host disease (cGVHD) consensus assessments are predictive of management across institutions with and without oral medicine (OM) centers, and whether ancillary care guidelines are followed within clinical practice. Methods Longitudinal oral cGVHD data were abstracted from the cGVHD Consortium and additional mouth-specific management data were analyzed across five transplant centers. Results Seventy-... περισσότερα »
Behavioral Analysis of Bitter Taste Perception
Behavioral Analysis of Bitter Taste Perception in Drosophila Larvae: Insect larvae, which recognize food sources through chemosensory cues, are a major source of global agricultural loss. Gustation is an important factor that determines feeding behavior, and the gustatory receptors (Grs) act as molecular receptors that recognize diverse chemicals in gustatory receptor neurons (GRNs). The behavior of *Drosophila* larvae is relatively simpler than the adult fly, and a gustatory receptor-to-neuron map was established in a previous study of the major external larval head sensory organs... περισσότερα »
Self-Reported Smell and Taste Alterations
Prevalence and Risk Factors of Self-Reported Smell and Taste Alterations: Results from the 2011-2012 US National Health and Nutrition Examination Survey (NHANES): Chemosensory problems challenge health through diminished ability to detect warning odors, consume a healthy diet, and maintain quality of life. We examined the prevalence and associated risk factors of self-reported chemosensory alterations in 3603 community-dwelling adults (aged 40+ years), from the nationally representative, US National Health and Nutrition Examination Survey (NHANES) 2011–2012. In this new NHANES com...περισσότερα »
The Olfactory, Nasal Trigeminal, and Ocular Trigeminal Detectability of Airborne Chemicals
Dose-Response Functions for the Olfactory, Nasal Trigeminal, and Ocular Trigeminal Detectability of Airborne Chemicals by Humans: We gathered from the literature 47 odor and 37 trigeminal (nasal and ocular) chemesthetic psychometric (i.e., detectability or dose–response) functions from a group of 41 chemicals. Vapors delivered were quantified by analytical methods. All functions were very well fitted by the sigmoid (logistic) equation: *y* = 1 / (1 + e{–(*x*–*C*)/*D*}), where parameter *C* quantifies the detection threshold concentration and parameter *D* the steepness of the funct... περισσότερα »
Rodents are strongly attracted to the taste(s) of maltodextrins. A first step toward discovery of the underlying genes involves identifying phenotypic differences
Maltodextrin Acceptance and Preference in Eight Mouse Strains: Rodents are strongly attracted to the taste(s) of maltodextrins. A first step toward discovery of the underlying genes involves identifying phenotypic differences among inbred strains of mice. To do this, we used 5-s brief-access tests and 48-h 2-bottle choice tests to survey the avidity for the maltodextrin, Maltrin M040, of mice from 8 inbred strains (129S1/SvImJ, A/J, CAST/EiJ, C57BL/6J, NOD/ShiLTJ, NZO/HlLtJ, PWK/PhJ, and WSB/EiJ). In brief-access tests, the CAST and PWK strains licked significantly less maltodextri...περισσότερα »
Arecoline Alters Taste Bud Cell Morphology
Arecoline Alters Taste Bud Cell Morphology, Reduces Body Weight, and Induces Behavioral Preference Changes in Gustatory Discrimination in C57BL/6 Mice: Arecoline, a major alkaloid in areca nuts, is involved in the pathogenesis of oral diseases. Mammalian taste buds are the structural unit for detecting taste stimuli in the oral cavity. The effects of arecoline on taste bud morphology are poorly understood. Arecoline was injected intraperitoneally (IP) into C57BL/6 mice twice daily for 1–4 weeks. After arecoline treatment, the vallate papillae were processed for electron microscopy... περισσότερα »
Olfactory Identification Patterns among Parkinsons Disease Patients
Comparison of Olfactory Identification Patterns among Parkinsons Disease Patients from Different Countries: Olfactory function assessment is an important screening tool and also may differentiate Parkinson’s disease (PD) patients from other parkinsonisms, including nondegenerative ones, such as, normal pressure hydrocephalus, vascular, drug induced, or infectious parkinsonism. Several authors in different countries have reported various sets of odors that best differentiate between these conditions. It is debated if distinctive patterns of "restrictive" or "selective" hyposmia in P... περισσότερα »
Human Chemosignals of Aggression
You Smell Dangerous: Communicating Fight Responses Through Human Chemosignals of Aggression: The ability to detect conspecifics that represent a potential harm for an individual represents a high survival benefit. Humans communicate socially relevant information using all sensory modalities, including the chemosensory systems. In study 1, we investigated whether the body odor of a stranger with the intention to harm serves as a chemosignal of aggression. Sixteen healthy male participants donated their body odor while engaging in a boxing session characterized by aggression-inductio...περισσότερα »
Enhancement of Odor-Induced Activity in the Brain by Zinc Nanoparticles
Enhancement of Odor-Induced Activity in the Canine Brain by Zinc Nanoparticles: A Functional MRI Study in Fully Unrestrained Conscious Dogs: Using noninvasive in vivo functional magnetic resonance imaging (fMRI), we demonstrate that the enhancement of odorant response of olfactory receptor neurons by zinc nanoparticles leads to increase in activity in olfaction-related and higher order areas of the dog brain. To study conscious dogs, we employed behavioral training and optical motion tracking for reducing head motion artifacts. We obtained brain activation maps from dogs in both an...περισσότερα »
Odorant Metabolism Analysis
Odorant Metabolism Analysis by an Automated Ex Vivo Headspace Gas-Chromatography Method: In the olfactory epithelium (OE), odorant metabolizing enzymes have the dual function of volatile component detoxification and active clearance of odorants from the perireceptor environment to respectively maintain the integrity of the tissues and the sensitivity of the detection. Although emphasized by recent studies, this enzymatic mechanism is poorly documented in mammals. Thus, olfactory metabolism has been characterized mainly in vitro and for a limited number of odorants. The automated ex... περισσότερα »
Salt and Fat Combinations on Taste Preference and Perception
Effects of Salt and Fat Combinations on Taste Preference and Perception: Fat and salt are a common and attractive combination in food and overconsumption of either is associated with negative health outcomes. The major aim was to investigate contributions and interactions of salt and fat on taste pleasantness and perception. The minor aim was to investigate individual fat taste sensitivity (detection threshold of oleic acid [C18:1]) on pleasantness for fat. In a complete factorial design, 49 participants (18–54 years, 12 males) tasted tomato soups with 4 different fat concentration...περισσότερα »
Fast detection of periodontal pathogens
Development of a point-of-care-device for fast detection of periodontal pathogens: Abstract BackgroundA number of pathogens can cause severe destruction of the periodontal apparatus during the course of periodontitis. The aim of this work was the development of a diagnostic device for the use at the point-of-need for the detection of periodontal pathogens to enable a personalized therapy for treatment of periodontitis. MethodsThis test system is based on the polymerase chain reaction of DNA isolated from periodontal pathogens and was examined to precisely detect species-specif... περισσότερα »
Blood and saliva expression profiles in chronic and refractory periodontitis patients
Comparative analysis of blood and saliva expression profiles in chronic and refractory periodontitis patients: Abstract BackgroundThis study aimed to identify characteristic representative genes through a comparative analysis of gene expression profiles in the blood and saliva of chronic periodontitis (CP) and refractory periodontitis (RP) patients to provide new treatment strategies that may be helpful in the treatment of different forms of periodontitis. MethodsGSE43525 was downloaded from Gene Expression Omnibus. In the dataset, thirteen samples were from blood including 4 c... περισσότερα »
The interactions between different tastes on initiation of reflex swallow elicited by electrical stimulation in humans
The interactions between different tastes on initiation of reflex swallow elicited by electrical stimulation in humans: AbstractThe act of eating is a source of pleasure for people and is a major factor in maintaining a good quality of life. Several types of products for dysphagia patients are available to decrease aspiration of food that often accompanies daily food intake. The final goal of these products is to improve the ease of forming a food bolus and/or the safety of the swallowing process; however, tastes of products are not a major concern with initiation of swallowing. In... περισσότερα »
Correction of nasal deformity in infants with unilateral cleft lip and palate
using multiple digital techniques via The Journal of Prosthetic Dentistry Publication date: Available online 24 December 2015 *Source:*The Journal of Prosthetic Dentistry Author(s): Yaqi Zheng, Dapeng Zhang, Tian Qin, Guofeng Wu Presurgical correction of severe nasal deformities before cheiloplasty is often recommended for infants with cleft lip and palate. This article describes an approach for the computer-aided design and fabrication of a nasal molding stent. A 3-dimensional photogrammetric system was used to obtain the shape information of the nosewing that was then built as the n...περισσότερα »
Equilibrium maintenance during single leg standing
Strategies for equilibrium maintenance during single leg standing on a wobble board via Gait & Posture Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Priscila de Brito Silva, Natalie Mrachacz-Kersting, Anderson Souza Oliveira, Uffe Laessoe, Uwe Gustav Kersting The aim of this study was to identify and compare movement strategies used to maintain balance while single leg standing on either a firm surface (FS) or on a wobble board (WB). In 17 healthy men, retroreflective markers were positioned on the xiphoid process and nondominant lateral malleolus to ca...περισσότερα »
Normal aging increases postural preparation errors
: Evidence from a two-choice response task with balance constraints via Gait & Posture Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Julius Verrel, Nina Lisofsky, Simone Kühn, Ulman Lindenberger Correlational studies indicate an association between age-related decline in balance and cognitive control, but these functions are rarely addressed within a single task. In this study, we investigate adult age differences in a two-choice response task with balance constraints under three levels of response conflict. Sixteen healthy young (20–30years) and 16 healt... περισσότερα »
3D displacement of the middle ear ossicles
in the quasi-static pressure regime using new X-ray stereoscopy technique via Hearing Research Publication date: Available online 23 December 2015 *Source:*Hearing Research Author(s): Wasil H.M. Salih, Joris J.A.M. Soons, Joris J.J. Dirckx A novel X-ray stereoscopy technique, using greyscale information obtained from moving markers, was used to study the 3D motion in both gerbil and rabbit middle ear ossicles in the quasi-static pressure regime. The motion can be measured without visually exposing the ossicles. The ossicles showed non-linear behaviour as a function of both pressure and...περισσότερα »
A single-ossicle ear
: acoustic response and mechanical properties measured in duck via Hearing Research Publication date: Available online 23 December 2015 *Source:*Hearing Research Author(s): Pieter G.G. Muyshondt, Joris A.M. Soons, Daniël De Greef, Felipe Pires, Peter Aerts, Joris J.J. Dirckx To date, the single-ossicle avian middle ear (ME) is poorly understood, despite its striking resemblance to the design of many currently used ossicular replacement prostheses. This study aims to improve comprehension of this system. The acoustic response and the mechanical properties of the mallard middle ear were ...περισσότερα »
The neural networks supporting intelligible speech processing
Acoustic richness modulates via Hearing Research Publication date: Available online 23 December 2015 *Source:*Hearing Research Author(s): Yune-Sang Lee, Nam Eun Min, Arthur Wingfield, Murray Grossman, Jonathan E. Peelle The information contained in a sensory signal plays a critical role in determining what neural processes are engaged. Here we used interleaved silent steady-state (ISSS) functional magnetic resonance imaging (fMRI) to explore how human listeners cope with different degrees of acoustic richness during auditory sentence comprehension. Twenty-six healthy young adults und... περισσότερα »
Simulating environmental and psychological acoustic factors of the operating room
Simulating environmental and psychological acoustic factors of the operating room: In this study, an operating room simulation environment was adapted to include quadraphonic speakers, which were used to recreate a composed clinical soundscape. To assess validity of the composed soundscape, several acoustic parameters of this simulated environment were acquired in the presence of alarms only, background noise only, or both. These parameters were also measured for comparison from size-matched operating rooms at Jackson Memorial Hospital. The parameters examined included sound level,... περισσότερα »
Mute Button For Tinitus
Mute Button For Tinitus: If you are searching for a mute button for tinitus, you are not alone. Tinnitus is one of the most bothersome auditory conditions that you may develop, and it affects millions of people each year. For many, the condition is characterized by a ringing sound, but the individual may also hear different sounds. These sounds include everything from a whirring sound to buzzing, static, chirping, whistling and more. These sounds may be heard throughout the day, making it difficult for many to go about their daily routine. For some, the condition may persist for ye... περισσότερα »
Chirp-Evoked Auditory Brainstem Response in Children
Chirp-Evoked Auditory Brainstem Response in Children: A Review: Purpose The aim of this study was to assess the use of the chirp stimulus to record auditory brainstem responses in the pediatric population via a traditional review. Method An electronic search of the literature and a hand search of the literature were conducted. Studies that utilized chirp stimuli within the pediatric population that met all of the inclusion criteria were included in this review. Qualitative synthesis and interpretation of the data were completed. Results Seven studies that met the inclusion crite... περισσότερα »
Test Condition on Speech Perception With Electric-Acoustic Stimulation
Influence of Test Condition on Speech Perception With Electric-Acoustic Stimulation: Purpose The goal of this work was to better understand speech perception for cochlear implant (CI) users with bilateral residual hearing, including consideration of effects related to listening conditions and test measures. Of interest was the role of acoustic hearing for speech perception in a complex background, the role of listening experience for CI-alone conditions, and whether performance with electric-acoustic stimulation (EAS) was improved by a contralateral hearing aid (HA). Method Eleve... περισσότερα »
Hearing Aid Use in the Classroom
Factors Influencing Hearing Aid Use in the Classroom: A Pilot Study: Purpose This pilot study examined factors influencing classroom hearing aid use in school-age children with hearing loss. Method The research team visited classrooms of 38 children with mild-to-moderate hearing loss (Grades 1–7) on 2 typical school days, twice per day, to document hearing aid use. In addition, parents reported the number of hours their children used hearing aids at school. Results Nearly 24% of children were observed not wearing their hearing aids in the classroom on either observation day. Both... περισσότερα »
Service Learning in Undergraduate Audiology Education
Service Learning in Undergraduate Audiology Education: Purpose The purpose of this study was to incorporate a service learning project in an undergraduate audiology course and evaluate how it affected student learning in the class. Method The study involved partnering with a group of students enrolled in a band learning community. Students in the audiology course learned about hearing assessment procedures in class and practiced the procedures on each other in labs. Toward the end of the semester, they assessed the hearing of the band students and provided counseling regarding the... περισσότερα »
Time of Onset of Hearing Loss (Childhood Versus Adulthood) and Self-Reported Hearing Handicap in Adults
No Association Between Time of Onset of Hearing Loss (Childhood Versus Adulthood) and Self-Reported Hearing Handicap in Adults: Purpose This study examined the association between time of onset of hearing loss (childhood vs. adulthood) and self-reported hearing handicap in adults. Methods This is a population-based cohort study of 2,024 adults (mean = 48 years) with hearing loss (binaural pure-tone average 0.5–4 kHz ≥ 20 dB HL) who completed a hearing handicap questionnaire. In childhood, the same persons ( N = 2,024) underwent audiometry in a school investigation (at ages 7, 10, a... περισσότερα »
Advancing Age on Auditory Middle- and Long-Latency Evoked Potentials Using a Steady-State-Response Approach
The Effect of Advancing Age on Auditory Middle- and Long-Latency Evoked Potentials Using a Steady-State-Response Approach: Purpose The purpose of the study was to objectively detect age-specific changes that occur in equivalent auditory steady-state responses (ASSRs), corresponding to transient middle- and long-latency auditory evoked potentials as a function of repetition rate and advancing age. Method The study included 48 healthy hearing adults who were equally divided into 3 groups by age: 20–39, 40–59, and 60–79 years. ASSRs were recorded at 7 repetition rates from 40 down to...περισσότερα »
Hearing Aid Self-Efficacy and Hearing Aid Satisfaction
The Relationship Between Hearing Aid Self-Efficacy and Hearing Aid Satisfaction: Purpose The purpose of this study was to investigate the relationship between self-efficacy for hearing aids (HAs) and satisfaction with HAs in a group of adult HA owners. Method Forty-seven adults acquiring HAs (new and experienced owners) completed a demographic questionnaire, the Hearing Handicap Questionnaire (Gatehouse & Noble, 2004), and received an audiometric evaluation prior to HA fitting. Twelve weeks following the completion of the HA fitting, they completed the Measure of Audiologic Rehab...περισσότερα »
Audiometric Thresholds: Stimulus Considerations in Sound Field and Under Earphones
Audiometric Thresholds: Stimulus Considerations in Sound Field and Under Earphones: Purpose This study evaluates a new stimulus, FREquency Specific Hearing assessment (FRESH) noise, to obtain hearing thresholds and reviews the potential pitfalls of using narrow band noise. Method Twelve adults with simulated gradually sloping hearing loss and 12 adults with steeply sloping hearing loss participated. Hearing thresholds were measured in sound field and under a supraaural earphone for FRESH noise, warbled tones, and narrowband noise. Pure-tone thresholds were also measured under the... περισσότερα »
Accelerometer-Determined Physical Activity: Considerations by Hearing Sensitivity
Accelerometer-Determined Physical Activity and Mortality in a National Prospective Cohort Study: Considerations by Hearing Sensitivity: Background Previous work demonstrates that hearing impairment and physical inactivity are associated with premature all-cause mortality. The purpose of this study was to discern whether increased physical activity among those with hearing impairment can produce survival benefits. Method Data from the 2003–2006 National Health and Nutrition Examination Survey were used, with follow-up through 2011. Physical activity was objectively measured over 7 ...περισσότερα »
Frequency Importance Functions in Quiet and Noise for Adults With Cochlear Implants
Frequency Importance Functions in Quiet and Noise for Adults With Cochlear Implants: Purpose Several studies have been devoted to understanding the frequency information available to adult users of cochlear implants when listening in quiet. The objective of this study was to construct frequency importance functions for a group of adults with cochlear implants and a group of adults with normal hearing both in quiet and in a +10 dB signal-to-noise ratio. Method Two groups of adults, 1 with cochlear implants and 1 with normal hearing, were asked to identify nonsense syllables in qui... περισσότερα »
Differences Among Patients That Make Their Tinnitus Worse or Better
Differences Among Patients That Make Their Tinnitus Worse or Better: Purpose Our objective was to identify activities that influence tinnitus and to determine if conditional probabilities exist among such variables. Method Two hundred fifty-eight patients were asked the following two questions: “When you have your tinnitus, which of the following makes it worse?” and “Which of the following reduces your tinnitus?” Results Things that made tinnitus better included noise (31%) and relaxation (15%). Things that made tinnitus worse included being in a quiet place (48%), stress (36%),... περισσότερα »
Retrospective Analysis of Decreasing the Use of Anesthesia in Pediatric Audiology: A Preliminary Study
Retrospective Analysis of Decreasing the Use of Anesthesia in Pediatric Audiology: A Preliminary Study: Purpose The purpose of this article is to analyze outcomes of processes aimed at reducing the need for use of anesthesia in evaluating pediatric hearing loss. Method A retrospective chart review was completed to assess how often a pediatric hearing evaluation was successful/not successful and auditory brainstem response (ABR) testing with anesthesia was avoided/required following review of orders for ABR testing with anesthesia. Results A total of 30% of the patients referred ...περισσότερα »
Reduction in High-Frequency Hearing Aid Gain Can Improve Performance in Patients With Contralateral Cochlear Implant: A Pilot Study
Reduction in High-Frequency Hearing Aid Gain Can Improve Performance in Patients With Contralateral Cochlear Implant: A Pilot Study: Purpose The purpose of this study was to determine whether an alternate fitting strategy, specifically adjustment to gains in a hearing aid (HA), would improve performance in patients who experienced poorer performance in the bimodal condition when the HA was fit to traditional targets. Method This study was a retrospective chart review from a local clinic population seen during a 6-month period. Participants included 6 users of bimodal stimulation. ... περισσότερα »
Guidelines for Audiologists on the Benefits and Limitations of Genetic Testing
Guidelines for Audiologists on the Benefits and Limitations of Genetic Testing: Purpose This tutorial provides information to aid audiologists in determining when a referral for a genetics evaluation is appropriate for a patient with hearing loss. Direction is given on discussing the benefits and limitations of genetic testing with parents of children with hearing loss. Method Genetic patterns of inheritance are reviewed, particularly in reference to syndromic and nonsyndromic forms of hearing loss. A review of pertinent literature was performed. Conclusion Audiologists are in a... περισσότερα »
Cortical and thalamic connectivity of the auditory anterior ectosylvian cortex of early-deaf
cats: Implications for neural mechanisms of crossmodal plasticity via Hearing Research Publication date: Available online 24 December 2015 *Source:*Hearing Research Author(s): M. Alex Meredith, H. Ruth Clemo, Sarah B. Corley, Nicole Chabot, Stephen G. Lomber Early hearing loss leads to crossmodal plasticity in regions of the cerebrum that are dominated by acoustical processing in hearing subjects. Until recently, little has been known of the connectional basis of this phenomenon. One region whose crossmodal properties are well-established is the auditory field of the anterior ectosylv...περισσότερα »
The paraflocculus on normal and abnormal spontaneous firing rates in the inferior colliculus
Influence of via Hearing Research Publication date: Available online 25 December 2015 *Source:*Hearing Research Author(s): Darryl P. Vogler, Donald Robertson, Wilhelmina H.A.M. Mulders Spontaneous firing rates of neurons in the central auditory pathway, such as in the inferior colliculus, are known to be increased after cochlear trauma. This so-called hyperactivity is thought to be involved in the generation of tinnitus, a phantom auditory perception. Recent research in an animal model suggests behavioural signs of tinnitus can be significantly reduced by silencing or removal of the p...περισσότερα »
Cochlear function related to acoustic stimulation of cervical vestibular evoked myogenic potential stimulation
Changes in via Hearing Research Publication date: Available online 25 December 2015 *Source:*Hearing Research Author(s): Anna-Karin Strömberg, Åke Olofsson, Magnus Westin, Maoli Duan, Stefan Stenfelt Evaluation of cervical evoked myogenic potentials (c-VEMP) is commonly applied in clinical investigations of patients with suspected neurotological symptoms. Short intense acoustic stimulation of peak levels close to 130 dB SPL is required to elicit the responses. A recent publication on bilateral significant sensorineural hearing loss related to extensive VEMP stimulation motivates eval...περισσότερα »
Treatment for Refractory Chronic Daily Headache
Update of Inpatient Treatment for Refractory Chronic Daily Headache: AbstractChronic daily headache (CDH) is a group of headache disorders, in which headaches occur daily or near-daily (>15 days per month) and last for more than 3 months. Important CDH subtypes include chronic migraine, chronic tension-type headache, hemicrania continua, and new daily persistent headache. Other headaches with shorter durations (<4 h/day) are usually not included in CDH. Common comorbidities of CDH are medication overuse headache and various psychiatric disorders, such as depression and anxiety. Ind... περισσότερα »
Castleman Disease of the Parotid Gland
Castleman Disease of the Parotid Gland: A Report of a Case: Castleman disease is an extremely rare benign lymphoproliferative disorder of unknown etiology. It affects the lymphatic chain in anybody region, although the commonest site is the mediastinum. The head and neck region is the second most common site; however, the salivary glands are rarely affected. We report a case of a 29-year-old Asian lady who presented with a 2-year history of an enlarging left parotid mass. Histopathology of the excisional biopsy confirmed the diagnosis of Castleman disease.
Temporal changes of antibiotic resistance genes and bacterial communities in two contrasting soils treated with cattle manure
The emerging environmental spread of antibiotic resistance genes (ARGs) and their subsequent acquisition by clinically-relevant microorganisms is a major threat to public health. Animal manure has been recognized as an important reservoir of ARGs, however, the dissemination of manure-derived ARGs and the impacts of manure application on the soil resistome remain obscure. Here, we conducted a microcosm study to assess the temporal succession of total bacteria and a broad-spectrum of ARGs in two contrasting soils following manure application from cattle which had not been treated wi...περισσότερα »
Abundance and potential metabolic activity of methanogens in well-aerated forest and grassland soils of an alpine region
Although methanogens were recently discovered to occur in aerated soils, alpine regions have not been extensively studied for their presence so far. Here, the abundance of archaea and the methanogenic guilds *Methanosarcinales*, *Methanococcales*, *Methanobacteriales*, *Methanomicrobiales*, and *Methanocella spp.* was studied at 16 coniferous forest and 14 grassland sites located at the montane and subalpine belts of the Northern Limestone Alps (calcareous) and the Austrian Central Alps (siliceous) using quantitative real-time PCR. Abundance of archaea, methanogens and the methano... περισσότερα »
Postoperative packing in FESS
How effective is postoperative packing in FESS patients? A critical analysis of published interventional studies: AbstractThe present study aimed to assess the clinical effectiveness of absorbable packing alone, non-absorbable packing alone, and absorbable versus non-absorbable packing in the postoperative care of FESS patients, regarding bleeding control, adhesion formation, wound healing, and overall patient comfort. Systematic literature review in Medline and other database sources until July 2013, and critical analysis of pooled data were conducted. Blinded prospective randomiz... περισσότερα »
Anemia
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Anemia: The condition of having a lower-than-normal number of red blood cells or quantity of hemoglobin. Anemia diminishes the capacity of the blood to carry oxygen. Patients with anemia may feel tired, fatigue easily, appear pale, develop palpitations, and become short of breath. Children with chronic anemia are prone to infections and learning problems. The […]
Quality Indicators in Pituitary Surgery: A Need for Reliable and Valid assessments. What should be measured?
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Engagement with improving the quality of clinical care is a key component of medical professionalism. Central to Quality Improvement (QI) agenda are the development of valid, reliable and accurate quality metrics. We can’t improve what we don’t measure. Pituitary surgery, which in the 21st century usually means trans-sphenoidal surgery (TSS), is unusual; it is […]
Association between lung capacity and abnormal glucose metabolism: Findings from China and Australia
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Objective Restricted pulmonary function is found among people with diabetes. This study aimed to investigate the dose-response relationship between pulmonary function measurements (forced expiratory volume in one second (FEV1) and forced vital capacity (FVC)) and risk of metabolic syndrome (MS) /type 2 diabetes. Methods 1,454 adults in rural Victoria, Australia and 5,824 adults in […]
The importance of knowing the timing within the menstrual cycle in non-menopausal hypertensive women in the diagnostic workup for primary aldosteronism
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract We read with interest the paper by Ahmed el al (1), which demonstrates the importance of knowing the timing within the menstrual cycle when a diagnostic test is done for primary aldosteronism in non-menopausal women, reporting greater percentages of positive fludrocortisone suppression tests in the luteal compared to the follicular phase. Interestingly, a positive […]
Response to letter to the Editor
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract We thank the authors for their positive and insightful comments. The close agreement between their results and ours certainly adds weight to the findings and conclusions of our study. We also thank them for their proposed explanation concerning the discrepancy in reported results of in vitro studies assessing the effects of progesterone on aldosterone […]
Clinicians’ Perspectives on Managing Symptom Clusters in Advanced Cancer: A Semi-Structured Interview Study
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Managing “symptom clusters,” or multiple concurrent symptoms in patients with advanced cancer remains a clinical challenge. The optimal processes constituting effective management of symptoms clusters remain uncertain. (Source: Journal of Pain and Symptom Management) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1ProNpE via IFTTT
How Accurately Do Consecutive Cohort Audits Predict Phase III Multisite Clinical Trial Recruitment in Palliative Care?
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Audits have been proposed for estimating possible recruitment rates to randomized controlled trials (RCTs) but few studies have compared audit data with subsequent recruitment rates. (Source: Journal of Pain and Symptom Management) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1YHuOq0 via IFTTT
Oral chronic GVHD outcomes and resource utilization: a subanalysis from the chronic GVHD consortium
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Objectives This study evaluated the extent to which oral chronic graft-versus-host disease (cGVHD) consensus assessments are predictive of management across institutions with and without oral medicine (OM) centers, and whether ancillary care guidelines are followed within clinical practice. Methods Longitudinal oral cGVHD data were abstracted from the cGVHD Consortium and additional mouth-specific management data […]
Clinicians’ Perspectives on Managing Symptom Clusters in Advanced Cancer: A Semi-Structured Interview Study
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Managing “symptom clusters,” or multiple concurrent symptoms in patients with advanced cancer remains a clinical challenge. The optimal processes constituting effective management of symptoms clusters remain uncertain. (Source: Journal of Pain and Symptom Management) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1ProNpE via IFTTT
How Accurately Do Consecutive Cohort Audits Predict Phase III Multisite Clinical Trial Recruitment in Palliative Care?
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Audits have been proposed for estimating possible recruitment rates to randomized controlled trials (RCTs) but few studies have compared audit data with subsequent recruitment rates. (Source: Journal of Pain and Symptom Management) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1YHuOq0 via IFTTT
Anemia
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Anemia: The condition of having a lower-than-normal number of red blood cells or quantity of hemoglobin. Anemia diminishes the capacity of the blood to carry oxygen. Patients with anemia may feel tired, fatigue easily, appear pale, develop palpitations, and become short of breath. Children with chronic anemia are prone to infections and learning problems. The […]
Quality Indicators in Pituitary Surgery: A Need for Reliable and Valid assessments. What should be measured?
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Engagement with improving the quality of clinical care is a key component of medical professionalism. Central to Quality Improvement (QI) agenda are the development of valid, reliable and accurate quality metrics. We can’t improve what we don’t measure. Pituitary surgery, which in the 21st century usually means trans-sphenoidal surgery (TSS), is unusual; it is […]
Association between lung capacity and abnormal glucose metabolism: Findings from China and Australia
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Objective Restricted pulmonary function is found among people with diabetes. This study aimed to investigate the dose-response relationship between pulmonary function measurements (forced expiratory volume in one second (FEV1) and forced vital capacity (FVC)) and risk of metabolic syndrome (MS) /type 2 diabetes. Methods 1,454 adults in rural Victoria, Australia and 5,824 adults in […]
The importance of knowing the timing within the menstrual cycle in non-menopausal hypertensive women in the diagnostic workup for primary aldosteronism
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract We read with interest the paper by Ahmed el al (1), which demonstrates the importance of knowing the timing within the menstrual cycle when a diagnostic test is done for primary aldosteronism in non-menopausal women, reporting greater percentages of positive fludrocortisone suppression tests in the luteal compared to the follicular phase. Interestingly, a positive […]
Response to letter to the Editor
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract We thank the authors for their positive and insightful comments. The close agreement between their results and ours certainly adds weight to the findings and conclusions of our study. We also thank them for their proposed explanation concerning the discrepancy in reported results of in vitro studies assessing the effects of progesterone on aldosterone […]
BenFred: Strauss befriended an intern – STLtoday.com
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
STLtoday.com BenFred: Strauss befriended an intern STLtoday.com If Strauss’ tongue was ever tied, I never saw it. Before Knight could begin his favorite activity outside of coaching college … He didn’t talk about the cancer much, at least not to me. The last time was the first time he brought it up. This was a […]
DMXL2 drives epithelial to mesenchymal transition in hormonal therapy resistant breast cancer through notch hyper-activation
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Oncotarget from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1mJBAdV via IFTTT
Identification of the regions involved in phonological assembly using a novel paradigm
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Brain and Language from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1UcWYTe via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1Prrs2I via IFTTT
DNA repair prognostic index modelling reveals an essential role for base excision repair in influencing clinical outcomes in ER negative and triple negative breast cancers
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Oncotarget from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1mJBAdI via IFTTT
The protein fraction from wheat-based dried distiller’s grain with solubles (DDGS): extraction and valorization
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
New Biotechnology from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1mJBwuv via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1Prrs2G via IFTTT
Dissecting tumor metabolic heterogeneity: Telomerase and large cell size metabolically define a sub-population of stem-like, mitochondrial-rich, cancer cells
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Oncotarget from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1UcWZ9G via IFTTT
Designer cell signal processing circuits for biotechnology
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
New Biotechnology from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1mJBvqE via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1RNeY8R via IFTTT
The pioneer factor PBX1 is a novel driver of metastatic progression in ERα-positive breast cancer
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Oncotarget from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1UcWXyI via IFTTT
Atomic structure of the APC/C and its mechanism of protein ubiquitination
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Nature from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1UcWX1M via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1PrrxU2 via IFTTT
Identification of the regions involved in phonological assembly using a novel paradigm
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Brain and Language from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1UcWYTe via IFTTT
Opposite malaria and pregnancy effect on oral bioavailability of artesunate – a population pharmacokinetic evaluation
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
British Journal of Clinical Pharmacology from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1UcWWL8 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1RNeXSD via IFTTT
Oral chronic GVHD outcomes and resource utilization: a subanalysis from the chronic GVHD consortium
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Objectives This study evaluated the extent to which oral chronic graft-versus-host disease (cGVHD) consensus assessments are predictive of management across institutions with and without oral medicine (OM) centers, and whether ancillary care guidelines are followed within clinical practice. Methods Longitudinal oral cGVHD data were abstracted from the cGVHD Consortium and additional mouth-specific management data […]
MiR-127-5p targets the biliverdin reductase B/NF-κB pathway to suppress cell growth in hepatocellular carcinoma cells
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Nuclear factor-kappa B (NF-κB) activation is one of the major mediators of inflammation-induced cancer cell growth and progression. In previous studies, we screened a series of microRNAs (miRNAs) that targeted NF-κB signaling pathway. In this study, we demonstrated that miR-127-5p suppressed NF-κB activity through inhibition of p65 nuclear translocation. In addition, miR-127-5p also inhibited […]
A sensitive cytometry based system for enumeration, capture and analysis of gene mutations of circulating tumor cells
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Summary Methods for the enumeration and molecular characterization of circulating tumor cells (CTCs) have been actively investigated. However, such methods are still technically challenging. We have developed a novel epithelial cell adhesion molecule independent CTC enumeration system integrated with a sorting system using a microfluidics chip. We compared the number of CTCs detected using our […]
Tumor growth suppression by the combination of nanobubbles and ultrasound
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract We previously developed novel liposomal nanobubbles (Bubble liposomes; BLs) that oscillate and collapse in an ultrasound field, generating heat and shock waves. We aimed to investigate the feasibility of cancer therapy by the combination of BLs and ultrasound (BLs + ultrasound). In addition, we investigated the anti-tumor mechanism of this cancer therapy. Colon-26 cells […]
MiR-127-5p targets the biliverdin reductase B/NF-κB pathway to suppress cell growth in hepatocellular carcinoma cells
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Nuclear factor-kappa B (NF-κB) activation is one of the major mediators of inflammation-induced cancer cell growth and progression. In previous studies, we screened a series of microRNAs (miRNAs) that targeted NF-κB signaling pathway. In this study, we demonstrated that miR-127-5p suppressed NF-κB activity through inhibition of p65 nuclear translocation. In addition, miR-127-5p also inhibited […]
A sensitive cytometry based system for enumeration, capture and analysis of gene mutations of circulating tumor cells
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Summary Methods for the enumeration and molecular characterization of circulating tumor cells (CTCs) have been actively investigated. However, such methods are still technically challenging. We have developed a novel epithelial cell adhesion molecule independent CTC enumeration system integrated with a sorting system using a microfluidics chip. We compared the number of CTCs detected using our […]
Tumor growth suppression by the combination of nanobubbles and ultrasound
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract We previously developed novel liposomal nanobubbles (Bubble liposomes; BLs) that oscillate and collapse in an ultrasound field, generating heat and shock waves. We aimed to investigate the feasibility of cancer therapy by the combination of BLs and ultrasound (BLs + ultrasound). In addition, we investigated the anti-tumor mechanism of this cancer therapy. Colon-26 cells […]
Pseudocarcinomatous Hyperplasia Hiding Lymphomatoid Papulosis: A «Low-Power View» Pitfall
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Pseudocarcinomatous hyperplasia (PCH) is a reactive proliferation of the epidermis that can be associated with many inflammatory and neoplastic conditions. Histologically, it is characterized by irregular strands of epidermis, usually at the level of the follicular infundibulum, projecting downward into the dermis. The differentiation between a well-differentiated squamous cell carcinoma and PCH can be particularly […]
Justin Bieber is on to something: our bedrock is the NHS – The Guardian
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
The Guardian Justin Bieber is on to something: our bedrock is the NHS The Guardian ‘I didn’t recognise how impressive the NHS is, from a distance’. Illustration by Robert G Fresson. Contact author. @zoesqwilliams. Sunday 27 December 2015 12.10 EST Last modified on Sunday 27 December 2015 17.00 EST. Share on Facebook · Share on […]
First Nations health advocate dies of asbestos-related cancer – Toronto Star
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Toronto Star First Nations health advocate dies of asbestos-related cancer Toronto Star Mesothelioma is a rare type of cancer that is often linked with exposure to asbestos. The World Health Organization maintains all types of asbestos can cause lung cancer, mesothelioma, cancer of the larynx and ovary, and asbestosis. ThunderSky was also … and more […]
The incidence rate over 10 years of naturally occurring, cancer related mutations in the basal core promoter of hepatitis B virus
Infection, Genetics and Evolution from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1mJBzGN via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1OucHza via IFTTT
Opposite malaria and pregnancy effect on oral bioavailability of artesunate – a population pharmacokinetic evaluation
British Journal of Clinical Pharmacology from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1UcWWL8 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1JDxYyQ via IFTTT
Atomic structure of the APC/C and its mechanism of protein ubiquitination
Nature from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1UcWX1M via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1OucJqQ via IFTTT
The protein fraction from wheat-based dried distiller’s grain with solubles (DDGS): extraction and valorization
New Biotechnology from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1mJBwuv via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1JDxSYe via IFTTT
BenFred: Strauss befriended an intern – STLtoday.com
STLtoday.com BenFred: Strauss befriended an intern STLtoday.com If Strauss’ tongue was ever tied, I never saw it. Before Knight could begin his favorite activity outside of coaching college … He didn’t talk about the cancer much, at least not to me. The last time was the first time he brought it up. This was a… Continue reading BenFred: Strauss befriended an intern – STLtoday.com
Ferritin family proteins and their use in bionanotechnology
New Biotechnology from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1UcWWuv via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1OucHz6 via IFTTT
MiR-127-5p targets the biliverdin reductase B/NF-κB pathway to suppress cell growth in hepatocellular carcinoma cells
Abstract Nuclear factor-kappa B (NF-κB) activation is one of the major mediators of inflammation-induced cancer cell growth and progression. In previous studies, we screened a series of microRNAs (miRNAs) that targeted NF-κB signaling pathway. In this study, we demonstrated that miR-127-5p suppressed NF-κB activity through inhibition of p65 nuclear translocation. In addition, miR-127-5p also inhibited… Continue reading MiR-127-5p targets the biliverdin reductase B/NF-κB pathway to suppress cell growth in hepatocellular carcinoma cells
A sensitive cytometry based system for enumeration, capture and analysis of gene mutations of circulating tumor cells
Summary Methods for the enumeration and molecular characterization of circulating tumor cells (CTCs) have been actively investigated. However, such methods are still technically challenging. We have developed a novel epithelial cell adhesion molecule independent CTC enumeration system integrated with a sorting system using a microfluidics chip. We compared the number of CTCs detected using our… Continue reading A sensitive cytometry based system for enumeration, capture and analysis of gene mutations of circulating tumor cells
Tumor growth suppression by the combination of nanobubbles and ultrasound
Abstract We previously developed novel liposomal nanobubbles (Bubble liposomes; BLs) that oscillate and collapse in an ultrasound field, generating heat and shock waves. We aimed to investigate the feasibility of cancer therapy by the combination of BLs and ultrasound (BLs + ultrasound). In addition, we investigated the anti-tumor mechanism of this cancer therapy. Colon-26 cells… Continue reading Tumor growth suppression by the combination of nanobubbles and ultrasound
Oral chronic GVHD outcomes and resource utilization: a subanalysis from the chronic GVHD consortium
Abstract Objectives This study evaluated the extent to which oral chronic graft-versus-host disease (cGVHD) consensus assessments are predictive of management across institutions with and without oral medicine (OM) centers, and whether ancillary care guidelines are followed within clinical practice. Methods Longitudinal oral cGVHD data were abstracted from the cGVHD Consortium and additional mouth-specific management data were analyzed across five transplant centers. Results Seventy-nine patients with 656 visits were observed for a median of 7.1 months with one visit per follow...περισσότερα »
Pseudocarcinomatous Hyperplasia Hiding Lymphomatoid Papulosis: A «Low-Power View» Pitfall
Pseudocarcinomatous hyperplasia (PCH) is a reactive proliferation of the epidermis that can be associated with many inflammatory and neoplastic conditions. Histologically, it is characterized by irregular strands of epidermis, usually at the level of the follicular infundibulum, projecting downward into the dermis. The differentiation between a well-differentiated squamous cell carcinoma and PCH can be particularly… Continue reading Pseudocarcinomatous Hyperplasia Hiding Lymphomatoid Papulosis: A «Low-Power View» Pitfall
How Accurately Do Consecutive Cohort Audits Predict Phase III Multisite Clinical Trial Recruitment in Palliative Care?
Audits have been proposed for estimating possible recruitment rates to randomized controlled trials (RCTs) but few studies have compared audit data with subsequent recruitment rates. (Source: Journal of Pain and Symptom Management) MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too. from #Medicine-Sfakianakis via simeraentaxei on… Continue reading How Accurately Do Consecutive Cohort Audits Predict Phase III Multisite Clinical Trial Recruitment in Palliative Care?
Clinicians’ Perspectives on Managing Symptom Clusters in Advanced Cancer: A Semi-Structured Interview Study
Managing “symptom clusters,” or multiple concurrent symptoms in patients with advanced cancer remains a clinical challenge. The optimal processes constituting effective management of symptoms clusters remain uncertain. (Source: Journal of Pain and Symptom Management) from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1kmWjlX via IFTTT
Prevalence and predictive factors of depression and anxiety in patients with pancreatic cancer: a longitudinal study
Conclusion A considerable percentage of pancreatic cancer patients experienced depression and anxiety. Multidimensional psychosocial predictive factors were found and optimal psychological care should incorporate early detection of sadness. (Source: Japanese Journal of Clinical Oncology) from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1QVG3Xo via IFTTT
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