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Τρίτη 26 Ιανουαρίου 2016

[A Case of Combined Modality Therapy for a Cervical Lymph Node Recurrence after Surgery for Esophageal Cancer].

[A Case of Combined Modality Therapy for a Cervical Lymph Node Recurrence after Surgery for Esophageal Cancer].

Gan To Kagaku Ryoho. 2015 Nov;42(12):1626-8

Authors: Murakami H, Nishikawa K, Hirao M, Yamamoto K, Maeda S, Uemura M, Miyake M, Hama N, Ohmiya H, Miyamoto A, Miyazaki M, Ikeda M, Takami K, Nakamori S, Sekimoto M

Abstract
Inthe present report, we describe a manwith type 2 progressive squamous cell carcinoma(cT3N1M0, cStage Ⅲ)that was detected inthe esophago-gastric junction during follow-up after ESD for early gastric cancer. We performed a middle inferior part esophagectomy, a 2-region dissection, and a posterior mediastinum gastric tube reconstruction after preoperative chemotherapy( docetaxel plus cisplatinplus 5-FU). The patient only received 1 course of preoperative chemotherapy because of neutropenia. The pathology results were pT3N2M0, pStage Ⅲ. Six months later, we started chemotherapy(nedaplatin plus adriamycinplus 5-FU)owing to an abdominal lymph node recurrence. We administered 3 courses, but then switched to radiotherapy because of AEs. After receiving a radiation dose of 50.4 Gy, the patient experienced a para-aortic lymph node recurrence and was administered 50.4 Gy for the new lesion, resulting in a CR. Six months later, we identified lymph node recurrences under the left superficialis neck muscle and performed left cervical lymph node resection. All 3 of the enlarged lymph nodes that we resected were found to contain a metastasis of esophageal cancer. Currently(after 6 months), there are no signs of recurrence.

PMID: 26805118 [PubMed - in process]



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