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The Hidden Culprit: A Case of Repeated Anaphylaxis to Cremophor.
Allergy Asthma Immunol Res. 2016 Mar;8(2):174-7
Authors: Kim YN, Kim JY, Kim JW, Kim JH, Kim HI, Yune S, Choi DC, Lee BJ
Abstract
Drug-induced anaphylaxis is a big pitfall in patients receiving antineoplastic chemotherapy. We report a case of lung cancer patient who experienced two near-fatal anaphylactic reactions that resulted from paclitaxel and multivitamin, seperately. Recurrent severe reactions to different agents led to further investigation to which material the patient was hypersensitive. The skin prick test revealed sensitization to cremophor, which is a commonly used emulsifying agent. This case emphasizes the importance of correctly identifying the culprit drug of anaphylaxis to avoid potentially fatal reaction.
PMID: 26739412 [PubMed]
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