Low-level laser therapy versus 5% amlexanox: a comparison of treatment effects in a cohort of patients with minor aphthous ulcers.

Low-level laser therapy versus 5% amlexanox: a comparison of treatment effects in a cohort of patients with minor aphthous ulcers.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2016 Mar;121(3):269-73

Authors: Jijin MJ, Rakaraddi M, Pai J, Jaishankar HP, Krupashankar R, Kavitha AP, Anjana R, Shobha R

Abstract
OBJECTIVE: The aim of the study was to compare the treatment effects of 5% amlexanox and low-level laser therapy (LLLT) in a cohort of patients who experienced minor aphthous stomatitis.
STUDY DESIGN: A clinical trial was performed between 2012 and 2014 on 50 participants having minor aphthous ulcers. Group A participants were treated with amlexanox oral paste (lexanox 5% oral paste), and group B participants were treated with LLLT. Pain scores and sizes of ulcers were measured on the first, third, and seventh days of treatment in both groups. Data were analyzed using paired t test and independent t test.
RESULTS: No significant difference was observed between the two groups with respect to pain level on the first and seventh days of treatment.
CONCLUSIONS: Both amlexanox and LLLT were equally effective in relieving pain associated with minor aphthous stomatitis. Both groups showed significant reduction in ulcer sizes and in pain scores.

PMID: 26868469 [PubMed - in process]

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