Laryngeal leishmaniasis in a patient taking inhaled corticosteroids.

Laryngeal leishmaniasis in a patient taking inhaled corticosteroids.

BMJ Case Rep. 2016;2016

Authors: Roberts RM, Mukherjee J, Phillips D

Abstract
We present a case of a man in his late 60s, who had spent 3-4 months of the year in rural Spain, presenting with intermittent hoarseness of voice. He had a background of asthma and bronchiectasis, and was taking inhaled corticosteroids. His dysphonia was initially managed as bronchiectasis with little improvement. Bronchoscopy revealed a cystic lesion on his left vocal fold, and tissue biopsy revealed Leishmania amastigotes. This confirmed a diagnosis of laryngeal leishmaniasis. We propose that this is likely secondary to his inhaled corticosteroid therapy. The infection was treated with a 30-day course of miltefosine, and at most recent follow-up the patient was deemed free from leishmanial infection.

PMID: 27329097 [PubMed - in process]

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