[Giant inflammatory pseudotumor of the cranial base].

[Giant inflammatory pseudotumor of the cranial base].

Neurocirugia (Astur). 2016 Jul 12;

Authors: Carrasco-Moro R, Martínez-San Millán J, Pian H

Abstract
The inflammatory pseudotumour (IPT) is a non-neoplastic entity of unknown origin, and is characterised by a proliferation of connective tissue and a polyclonal inflammatory infiltrate. Central nervous system involvement is uncommon, and usually represents a diagnostic and therapeutic challenge even for the experienced clinician. This reports deals with the case of a 56year-old woman diagnosed with a giant, infiltrating mass centred in the left cavernous sinus, who had a rapid clinical and radiological response to steroid therapy. Biopsy specimens were diagnostic for IPT. The progression of a small orbital residual lesion was detected after steroid withdrawal. Treatment with cyclophosphamide induced a complete response that remains stable after six years of follow-up.

PMID: 27422698 [PubMed - as supplied by publisher]

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