Spinal Schwannoma and Meningioma Mimicking a Single Mass at the Craniocervical Junction Subsequent to Remote Radiation Therapy for Acne Vulgaris.

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Spinal Schwannoma and Meningioma Mimicking a Single Mass at the Craniocervical Junction Subsequent to Remote Radiation Therapy for Acne Vulgaris.

World Neurosurg. 2016 Jul 19;

Authors: Liebelt BD, Haider AS, Steele WJ, Krishna C, Blacklock JB

Abstract
BACKGROUND: Schwannomas and meningiomas are relatively common tumors of the nervous system. They have been reported in the literature as existing concurrently as a single mass, but very rarely have been shown to present at the craniocervical junction.
CASE DESCRIPTION: In this study, we present a rare and interesting case of a patient previously treated with radiation therapy for acne vulgaris and presented to us with a concurrent schwannoma and meningioma of the craniocervical junction mimicking a single mass.
CONCLUSION: These tumors can be solitary or mixed masses, and are known to be associated with certain disease processes such as long-term sequelae of radiation therapy and neurofibromatosis type 2. The precise mechanism behind the formation of these tumors is unknown; however, molecular cues in the tumor microenvironment may play a role.

PMID: 27450976 [PubMed - as supplied by publisher]

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