Nine Patients with Chronic Granulomatous Disease Having Selective Neck Dissection for Severe Cervical Lymphadenitis.

Nine Patients with Chronic Granulomatous Disease Having Selective Neck Dissection for Severe Cervical Lymphadenitis.

Clin Otolaryngol. 2017 Jul 20;:

Authors: Wingfield LR, Liu J, Hu M, Bianchi D, Hauck K, Driscoll B, Gallin JI, Malech HL, Holland SM, Van Waes C

Abstract
Chronic Granulomatous Disease (CGD) is a rare, inherited disorder due to an X-linked or autosomal genetic defect, in which patients experience a high rate of lymphadenitis. To date, no studies have examined the best treatment for severe lymphadenitis in this patient population. We present a nine CGD patient retrospective case series, examining surgical treatment of cervical lymphadenitis. Our evolving surgical strategy shows that an initially more aggressive surgical approach (selective neck dissection) can help prevent recurrent infection. The results found within this patient population may be relevant to other multi-nodal disease, including cancers of the head and neck region, while preserving functional and cosmetically acceptable outcomes. This article is protected by copyright. All rights reserved.

PMID: 28727298 [PubMed - as supplied by publisher]

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