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Life-threatening Bleed Secondary to Tumor Shrinkage Effectively Palliated with Radiotherapy.
Cureus. 2017 Jun 24;9(6):e1386
Authors: Tseng M, Yew W, Jeyasekharan A, Vellayappan B
Abstract
Inverted papilloma is a typically benign, but locally aggressive tumor arising from the nasal cavity and paranasal sinuses. Malignant transformation can occur in up to 10% of cases. Although spontaneous tumor bleeding can occur with malignancies, hemorrhage secondary to tumor shrinkage has not been reported. We present a patient with metastatic squamous cell carcinoma (from inverted papilloma) who developed a life-threatening bleed shortly after chemotherapy initiation. She was managed successfully with life-saving palliative radiotherapy (RT), delivered based on clinical markup. She was subsequently re-treated with highly conformal RT and chemotherapy to achieve a marked clinical response without surgery.
PMID: 28775926 [PubMed]
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