S198 Different region-specific networks sustain focal seizures with a fast-activity onset: Evidence from patients and animal models

Focal seizure patterns generated by different cortical networks are not well characterized. I will provide evidence that different seizure patterns are generated by specific brain regions explored with stereo-EEG in patients with drug-resistant focal epilepsy candidate for surgery. Two main patterns typical of temporo-mesial involvement and neocortical involvement are identified. These two patterns were reproduced in an in vitro isolated brain preparation to characterize the network and cellular determinants.

from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/2vcAbBp