Source:Sleep Medicine
Author(s): Jaana K. Huhtakangas, Juha Huhtakangas, Risto Bloigu, Tarja Saaresranta
ObjectiveThe aim of the study was to compare the prevalence, type, and severity of sleep apnea during the acute phase of ischemic stroke among patients either receiving or not receiving thrombolysis.MethodsWe recruited 246 consecutive adult ischemic stroke patients. Patients underwent cardiorespiratory sleep study with portable 3-channel device during the first 48 hours after the symptom onset of ischemic stroke.ResultsWe enrolled 110 (65.5% male) stroke patients in the thrombolysis group and 94 (59.6% male) in the nonthrombolysis group. In the thrombolysis group, the median National Institutes of Health Stroke Scale (NIHSS) score was higher (5.5) compared to the nonthrombolysis group (2.0) (p < 0.001). There was a lower incidence of lacunar (17.3% vs 36.2%, p = 0.002) and cerebellar (2.7% vs 16.0%, p < 0.001) strokes and a higher frequency of middle cerebral artery syndrome (60.9% vs 33.0%, p < 0.001) in the thrombolysis group compared to the nonthrombolysis group. Sleep apnea defined as an apnea−hypopnea index (AHI) ≥ 5/h was diagnosed in 186 (91.2%) patients, its prevalence being higher in the thrombolysis (96.4%) compared to the nonthrombolysis (85.1%) group (p = 0.007). The mean baseline AHI was 33.7/h in the thrombolysis group compared to 26.8/h in the nonthrombolysis group (p = 0.017).ConclusionSleep apnea was present in the vast majority of ischemic stroke patients. The stroke patients treated with thrombolysis were more likely to have sleep apnea, to have elevated NIHSS score at admission, and to be younger. Sleep apnea was more severe among those receiving thrombolysis as compared to those who were not.Clinical Trial RegistrationURL: http://ift.tt/2y3J4iO. Unique identifier: NCT01861275.
from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/2y0yuf1
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