Publication date: February 2018
Source:Oral Oncology, Volume 77
Author(s): Michael Huo, Benedict Panizza, Anne Bernard, Sandro V. Porceddu
ObjectivesTo determine the rate of subsequent primary site failure in patients with head and neck squamous cell carcinoma of unknown primary (UKP HNSCC) in a region with a high prevalence of cutaneous squamous cell carcinoma, according to a pre-determined institutional policy. Secondary aims included regional and distant control, and overall survival.Material and methodsPatients presenting between April 2005 and June 2016 to the Princess Alexandra Hospital Head and Neck Multidisciplinary Meeting with UKP HNSCC from either presumed mucosal or cutaneous sites treated with curative intent were eligible. Patients with presumed mucosal origin were treated with radiation therapy (RT) with or without chemotherapy, while patients with presumed cutaneous SCC were treated with surgery and post-operative RT with or without chemotherapy.ResultsA total of 63 patients met the inclusion criteria. Median follow up duration was 3.9 years (IQR 2.07-5.14). There were no subsequent primary site failures. The rate of nodal failure among presumed mucosal patients was 11.5%, and 8.1% among presumed cutaneous patients. The rate of distant metastatic failure was 11.1% among all patients. The estimated 5 year overall survival was 71.2% (95% CI 59.2–85.7%).ConclusionTreatment according to our pre-defined institutional policy for UKP HNSCC in a region with a high prevalence of cutaneous SCC appears to be safe and effective with low rates of mucosal primary emergence and nodal failure.
from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/2BHZmzK
Αρχειοθήκη ιστολογίου
-
►
2023
(269)
- ► Φεβρουαρίου (133)
- ► Ιανουαρίου (136)
-
►
2022
(2046)
- ► Δεκεμβρίου (165)
- ► Σεπτεμβρίου (161)
- ► Φεβρουαρίου (165)
-
►
2021
(3028)
- ► Δεκεμβρίου (135)
- ► Σεπτεμβρίου (182)
- ► Φεβρουαρίου (324)
-
►
2020
(1051)
- ► Δεκεμβρίου (292)
- ► Σεπτεμβρίου (60)
- ► Φεβρουαρίου (28)
-
►
2019
(2277)
- ► Δεκεμβρίου (18)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (89)
-
►
2018
(26280)
- ► Δεκεμβρίου (189)
- ► Φεβρουαρίου (6130)
- ► Ιανουαρίου (7050)
-
▼
2017
(33948)
-
▼
Δεκεμβρίου
(6715)
-
▼
Δεκ 21
(210)
- Comparison of the CIELab and CIEDE 2000 Color Diff...
- Marginal Fit of Metal-Ceramic Copings: Effect of L...
- The underreporting of cost perspective in cost-ana...
- Negative-delay sources in distortion product otoac...
- Intentional switching in auditory selective attent...
- Olivocochlear Efferents: Their action, effects, me...
- Use of the hCONSORT Criteria as a Reporting Standa...
- Progress in surgical strategies for treatment of s...
- Red and processed meat consumption and breast canc...
- Optimal adjuvant endocrine treatment of ER+/HER2+ ...
- 3-Methoxytyramine: An independent prognostic bioma...
- Real-World Experience with Targeted Therapy for th...
- Recent Pregnancy Is Not Associated with High-Risk ...
- Re: “Low-Dose Childhood Radiation Effects to the T...
- Rutin Scavenges Reactive Oxygen Species, Inactivat...
- Cancer Risk Associated with Nuclear Atypia in Cyto...
- Bone microarchitecture and bone mineral density in...
- Progress in surgical strategies for treatment of s...
- Strategies for Reducing Fatal Complications in Lip...
- Autophagy and proteostasis in the control of synap...
- LIF drives neural remodeling in pancreatic cancer ...
- Tumor side as model of integrative molecular class...
- Alteration of the tumor stroma using a consensus D...
- Biomarker Based Therapy in Pancreatic Ductal Adeno...
- The underreporting of cost perspective in cost-ana...
- Cost-effectiveness of adjuvant intravaginal brachy...
- Anticholinergics for asthma: a long history
- Editorial introductions
- Collection of nasal secretions and tears and their...
- Role of epigenetics and DNA-damage in asthma
- Association between allergic and nonallergic rhini...
- Update on questionnaires for assessing adherence t...
- Asthma versus chronic obstructive pulmonary diseas...
- Drug-induced anaphylaxis: is it an epidemic?
- The Influence of Gender and Age on the Acoustic Vo...
- Discussion: Abdominal Contouring Outcomes in Class...
- Comment on: Complications and Treatment Strategy A...
- Public Interest in Breast Augmentation: Analysis a...
- Expander/Implant Removal After Breast Reconstructi...
- Commentary for Modified Island Technique for Promi...
- Preoperative Evaluation is not Predictive of Trans...
- Endotracheal Tube Connector: Holding Breaths!
- The Effect of High-Frequency, Structured Expert Fe...
- Why a Proactive Perioperative Medicine Policy Is C...
- Intravenous Iron for Treatment of Anemia in the 3 ...
- Prospective Observational Study of Intraoperative ...
- Continuous Noninvasive Arterial Pressure Monitorin...
- Misaligned Feeding May Aggravate Pain by Disruptio...
- Extracorporeal Membrane Oxygenation Appropriatenes...
- Significance of Body Mass Index for Postoperative ...
- Tube Thoracostomy Complications: More to Learn
- Radical Nephrectomy for Primary Retroperitoneal Li...
- Pen Torch Transillumination: Difficult Venepunctur...
- Scientific Integrity Issues to Discuss
- The World Journal of Surgery Announces Julie Ann S...
- Intracorporeal Traction of the Rectum with a Beade...
- A Novel Lateral Approach to the Assessment of Voca...
- Impact of Abdominal Wall Hernias and Repair on Pat...
- Inhibition of the receptor for advanced glycation ...
- Predictive Modeling of Hamstring Strain Injuries i...
- Effect of Carbohydrate Mouth Rinse on Performance ...
- Physiatry Reviews for Evidence in Practice (PREP) ...
- Limbic and Basal Ganglia Neuroanatomical Correlate...
- Intraarticular Triamcinolone versus Hyaluronate In...
- Some Autonomic Deficits of Acute or Chronic Cervic...
- IMMUNE RESPONSES OF HLA-HIGHLY-SENSITIZED AND NONS...
- EM Nerd-The Case of the Aimless Convoy Continues
- Paraneoplastic Optic Neuropathy and Pineal Germino...
- Herpes Zoster Optic Neuropathy
- Immediate Effects of External Vibration Therapy vs...
- Trustworthy Otolaryngology Clinical Practice Guide...
- Industry Relationships Among Authors of Otolaryngo...
- Nasopharyngeal Swelling After Sinus Surgery for Cy...
- Hypercoagulability and Severe Obstructive Sleep Ap...
- Addition to Funding/Support
- Prevalence of Laryngeal Cleft in Patients With Eso...
- Generalized Radiopacities of the Craniofacial Skel...
- Indirect vs Direct Voice Therapy for Children With...
- Hypercoagulability and Severe Obstructive Sleep Apnea
- Genomic Profiling Tests Cleared by FDA Can Help Gu...
- Interaction of the epigenetic integrator UHRF1 wit...
- Factors Associated with 60-Day Readmission Followi...
- Cervicothoracoscopic Approach in Esophagectomy
- The Annals of Surgical Oncology : An Oncology Jour...
- When Should Negative Endobronchial Ultrasonography...
- Minimally Invasive and Open Approaches to Mediasti...
- Redefining the Ki-67 Index Stratification for Low-...
- Systematic Review of Cytoreductive Surgery and Bev...
- Adjuvant Chemoradiotherapy is Associated with Impr...
- Locally Advanced Colorectal Cancer: True Peritonea...
- Natural Disasters – Impact on Physicians and Resea...
- The activation and function of IL-36γ in neutrophi...
- CD151, A Novel Host Factor of Nuclear Export Signa...
- The Western Environment Reduces Innate Immune Cyto...
- Are We What Our Mothers Made Us? Lessons from Epig...
- LRP-1 Attenuates House Dust Mite-induced Eosinophi...
- Epidemiologic Patterns of In-Hospital Anaphylaxis ...
- Image-Guided Proper Liver Segmentectomy
- Emergency-to-Elective Surgery Ratio: A Global Indi...
- Splenic Infarction as a Delayed Febrile Complicati...
-
▼
Δεκ 21
(210)
- ► Σεπτεμβρίου (6470)
-
▼
Δεκεμβρίου
(6715)
-
►
2016
(4179)
- ► Σεπτεμβρίου (638)
- ► Φεβρουαρίου (526)
- ► Ιανουαρίου (517)
Πέμπτη 21 Δεκεμβρίου 2017
Head and neck squamous cell carcinoma of unknown primary: Outcomes of a pre-defined institutional treatment policy in a region with a high prevalence of skin cancer
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου