Assessing miRNAs profile expression as a risk stratification biomarker in oral potentially malignant disorders: A systematic review

Lip, oral cavity and oropharyngeal cancer (OCC-OPC) continues to be a significant worldwide health problem. The global estimated incidence of OCC-OPC is projected to rise by 66.4% by 2030; it specifically will increase from 442,760 in 2012 to 666,432 in 2030 [1]. It is also estimated that OCC-OPC will be responsible for 368,684 deaths in 2030 from that estimated of 241,458 in 2012 [1]. Oral squamous cell carcinoma (OSCC) is the most common form and accounts 95% of all oral malignancies [2]. The prevalence of OSCC is highly related to the consumption of tobacco, smoking, alcohol drinking, betel quid chewing, the presence of human papillomavirus (HPV) and the presence of other carcinogenic stimuli [2–4].

from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/2Dua7K9