Durable Clinical and Immunologic Advantage of Living Donor Liver Transplantation in Children

ABSTRACTBackgroundDespite high survival in pediatric living donor liver transplantation (LDLT), only 10% of liver transplants in children in the United States are from living donors, reflecting reluctance to embrace this approach. In addition to optimal timing and graft quality, LDLT may offer immunologic benefit since most donors are haplo-identical parents. We sought to quantify the benefit of LDLT compared to deceased donor liver transplantation (DDLT) using granular clinical and immunologic outcomes over the long-term.MethodsA retrospective cohort of children (age

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