Selective slow-wave sleep suppression affects the testosterone level at the next morning

Introduction: Testosterone (T) and cortisol (C) are major final products of the hypothalamic-pituitary-gonadal system and the hypothalamic-pituitary-adrenal system, respectively. The testosterone/cortisol (T/C) ratio is a marker of anabolic/catabolic physiological processes. The balance of T and C modulates psychologically and physically integrated human responses. The levels of these hormones display circadian variation: the highest T and C concentrations occur at the beginning of the day, while the lowest levels occur in the evening.

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